Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes

Journal of Biomedical Informatics

Volumn 55, Issue , 2015, Pages 94-103

  Gardeux, Vincent ^a   Bosco, Anthony ^b   Li, Jianrong ^a   Halonen, Marilyn J ^a   Jackson, Daniel ^c,d   Martinez, Fernando D ^a,d,e   Lussier, Yves A ^a,e,f  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d The Childhood Asthma Research and Education Network (CARE)   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

^f UNIVERSITY OF ARIZONA   (United States)

Author keywords

Genomic response; PBMC; Personal transcriptome; Rhinovirus; Similarity Venn Diagrams; Virogram

Indexed keywords

ASSAYS; DYNAMIC RESPONSE; GENES; VIRUSES;

GENOMIC RESPONSE; PBMC; RHINOVIRUS; TRANSCRIPTOMES; VENN DIAGRAMS; VIROGRAM;

PATIENT TREATMENT;

TRANSCRIPTOME; MESSENGER RNA;

ACCURACY; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; GENE CONTROL; GENE ONTOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; INCUBATION TIME; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RHINOVIRUS; VIROGRAM; VIRUS INFECTION; VIRUS TRANSCRIPTION; BIOASSAY; CELL CULTURE; COMPARATIVE STUDY; GENE EXPRESSION PROFILING; GENETIC DATABASE; GENETICS; MONONUCLEAR CELL; PERSONALIZED MEDICINE; PICORNAVIRUS INFECTION; PROCEDURES; SIGNAL TRANSDUCTION; VIROLOGY;

BIOLOGICAL ASSAY; CELLS, CULTURED; DATABASES, GENETIC; GENE EXPRESSION PROFILING; HUMANS; LEUKOCYTES, MONONUCLEAR; PICORNAVIRIDAE INFECTIONS; PRECISION MEDICINE; RHINOVIRUS; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84930725220     PISSN: 15320464     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbi.2015.03.003     Document Type: Article

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