Dentatin from clausena excavata induces apoptosis in HepG2 cells via mitochondrial mediated signaling

Asian Pacific Journal of Cancer Prevention

Volumn 16, Issue 10, 2015, Pages 4311-4316

  Andas, A Reenaa Joys ^a,b   Abdul, Ahmad Bustamam ^a   Rahman, Heshu Sulaiman ^a   Sukari, Mohd Aspollah ^c   Abdelwahab, Siddig Ibrahim ^d   Samad, Nozlena Abdul ^a   Anasamy, Theebaa ^a   Arbab, Ismail Adam ^a  

^a UPM MAKNA Cancer Research Laboratory Institute of Bioscience   (Malaysia)

^b Clinical Research Centre   (Malaysia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^d JAZAN UNIVERSITY   (Saudi Arabia)

Author keywords

Apoptosis; Dentatin; HepG2; Mitochondrial mediated signaling pathway

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DENTATIN; FUSED HETEROCYCLIC RINGS; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL X;

APOPTOSIS; CELL PROLIFERATION; CLAUSENA; DRUG EFFECTS; G1 PHASE CELL CYCLE CHECKPOINT; HEPG2 CELL LINE; HUMAN; IC50; LIVER MITOCHONDRION; METABOLISM; PLANT ROOT; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CASPASE 9; CELL PROLIFERATION; CLAUSENA; CYTOCHROMES C; G1 PHASE CELL CYCLE CHECKPOINTS; HEP G2 CELLS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; INHIBITORY CONCENTRATION 50; MITOCHONDRIA, LIVER; NF-KAPPA B; PLANT EXTRACTS; PLANT ROOTS; SIGNAL TRANSDUCTION;

EID: 84930723572     PISSN: 15137368     EISSN: None     Source Type: Journal    
DOI: 10.7314/APJCP.2015.16.10.4311     Document Type: Article

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