Activin a directs striatal projection neuron differentiation of human pluripotent stem cells

Development (Cambridge)

Volumn 142, Issue 7, 2015, Pages 1375-1386

  Arber, Charles ^a   Precious, Sophie V ^b   Cambray, SerafıÍ ^c   Risner Janiczek, Jessica R ^a   Kelly, Claire ^b   Noakes, Zoe ^b   Fjodorova, Marija ^b   Heuer, Andreas ^b   Ungless, Mark A ^a   Rodríguez, Tristan A ^c   Rosser, Anne E ^b   Dunnett, Stephen B ^b   Li, Meng ^a,b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Activin; DARPP32 (PPP1R1B); Huntington s disease; Lateral ganglionic eminence; Medium spiny neuron; Neural differentiation; Pluripotent stem cell; Striatum; Transplantation

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN A; CALBINDIN 1; DORSOMORPHIN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 67; TYROSINE 3 MONOOXYGENASE; VESICULAR GLUTAMATE TRANSPORTER 1; ACTIVIN; BCL11B PROTEIN, RAT; PHOSPHOPROTEIN DARPP 32; PPP1R1B PROTEIN, RAT; REPRESSOR PROTEIN; SONIC HEDGEHOG PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ACTION POTENTIAL; ANIMAL CELL; ANTIBODY LABELING; ARTICLE; CELL POPULATION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; ELECTROPHYSIOLOGICAL PROCEDURES; ELECTROPHYSIOLOGY; EMBRYO; FOREBRAIN; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERNEURON; MARKER GENE; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUBSTANTIA NIGRA PARS RETICULATA; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EMBRYONIC STEM CELL; GANGLION; HUNTINGTON DISEASE; METABOLISM; NEOSTRIATUM; NERVE CELL; PATHOLOGY; RAT; SIGNAL TRANSDUCTION; TRANSPLANTATION;

ERINACEIDAE; RATTUS;

ACTIVINS; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; EMBRYONIC STEM CELLS; GABAERGIC NEURONS; GANGLIA; HEDGEHOG PROTEINS; HUMANS; HUNTINGTON DISEASE; NEOSTRIATUM; NEURONS; PLURIPOTENT STEM CELLS; RATS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84930721799     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.117093     Document Type: Article

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