-
1
-
-
84856592577
-
Tumor control versus adverse events with targeted anticancer therapies
-
Keefe D.M., Bateman E.H. Tumor control versus adverse events with targeted anticancer therapies. Nat. Rev. Clin. Oncol. 2011, 9(2):98-109.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.9
, Issue.2
, pp. 98-109
-
-
Keefe, D.M.1
Bateman, E.H.2
-
2
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H., Sawyers C., Hochhaus A., Guilhot F., Schiffer C., Gambacorti-Passerini C., Niederwieser D., Resta D., Capdeville R., Zoellner U., Talpaz M., Druker B. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N. Engl. J. Med. 2002, 346:645-652.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Gambacorti-Passerini, C.6
Niederwieser, D.7
Resta, D.8
Capdeville, R.9
Zoellner, U.10
Talpaz, M.11
Druker, B.12
-
3
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond E.H., Perez E.A., Bryant J., Suman V.J., Geyer C.E., Davidson N.E., Tan-Chiu E., Martino S., Paik S., Kaufman P.A., Swain S.M., Pisansky T.M., Fehrenbacher L., Kutteh L.A., Vogel V.G., Visscher D.W., Yothers G., Jenkins R.B., Brown A.M., Dakhil S.R., Mamounas E.P., Lingle W.L., Klein P.M., Ingle J.N., Wolmark N. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 2005, 353:1673-1684.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer, C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
4
-
-
77955355467
-
Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer
-
Reguart N., Cardona A.F., Rosell R. Role of erlotinib in first-line and maintenance treatment of advanced non-small-cell lung cancer. Cancer Manag. Res. 2010, 2:143-156.
-
(2010)
Cancer Manag. Res.
, vol.2
, pp. 143-156
-
-
Reguart, N.1
Cardona, A.F.2
Rosell, R.3
-
5
-
-
84864464562
-
Reducing the toxicity of cancer therapy: recognizing needs, taking action
-
Cleeland C.S., Allen J.D., Roberts S.A., Brell J.M., Giralt S.A., Khakoo A.Y., Kirch R.A., Kwitkowski V.E., Liao Z., Skillings J. Reducing the toxicity of cancer therapy: recognizing needs, taking action. Nat. Rev. Clin. Oncol. 2012, 9:471-478.
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 471-478
-
-
Cleeland, C.S.1
Allen, J.D.2
Roberts, S.A.3
Brell, J.M.4
Giralt, S.A.5
Khakoo, A.Y.6
Kirch, R.A.7
Kwitkowski, V.E.8
Liao, Z.9
Skillings, J.10
-
6
-
-
84865687710
-
Targeted therapies: the toxic reality of new drugs
-
Kirk R. Targeted therapies: the toxic reality of new drugs. Nat. Rev. Clin. Oncol. 2012, 9(9):488.
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, Issue.9
, pp. 488
-
-
Kirk, R.1
-
7
-
-
84865165918
-
The price we pay for progress: a meta-analysis of harms of newly approved anticancer drugs
-
Niraula S., Seruga B., Ocana A., Shao T., Goldstein R., Tannock I.F., Amir E. The price we pay for progress: a meta-analysis of harms of newly approved anticancer drugs. J. Clin. Oncol. 2012, 30(24):3012-3019.
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.24
, pp. 3012-3019
-
-
Niraula, S.1
Seruga, B.2
Ocana, A.3
Shao, T.4
Goldstein, R.5
Tannock, I.F.6
Amir, E.7
-
8
-
-
78650383580
-
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology
-
Eschenhagen T., Force T., Ewer M.S., de Keulenaer G.W., Suter T.M., Anker S.D., Avkiran M., de Azambuja E., Balligand J., Brutsa D.L., Condorelli G., Hansen A., Heymans S., Hill J.A., Hirsch E., Hilfiker-Kleiner D., Janssens S., de Jong S., Neubauer G., Pieske B., Ponikowski P., Pirmohamed M., Rauchhaus M., Sawyer D., Sugden P.H., Wojta J., Zannad F., Shah A.M. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur. J. Heart Fail. 2011, 13(1):1-10.
-
(2011)
Eur. J. Heart Fail.
, vol.13
, Issue.1
, pp. 1-10
-
-
Eschenhagen, T.1
Force, T.2
Ewer, M.S.3
de Keulenaer, G.W.4
Suter, T.M.5
Anker, S.D.6
Avkiran, M.7
de Azambuja, E.8
Balligand, J.9
Brutsa, D.L.10
Condorelli, G.11
Hansen, A.12
Heymans, S.13
Hill, J.A.14
Hirsch, E.15
Hilfiker-Kleiner, D.16
Janssens, S.17
de Jong, S.18
Neubauer, G.19
Pieske, B.20
Ponikowski, P.21
Pirmohamed, M.22
Rauchhaus, M.23
Sawyer, D.24
Sugden, P.H.25
Wojta, J.26
Zannad, F.27
Shah, A.M.28
more..
-
9
-
-
77957306355
-
Cardiotoxicity of anticancer treatments: what the cardiologist needs to know
-
Ewer M.S., Ewer S.M. Cardiotoxicity of anticancer treatments: what the cardiologist needs to know. Nat. Rev. Cardiol. 2010, 7(10):564-575.
-
(2010)
Nat. Rev. Cardiol.
, vol.7
, Issue.10
, pp. 564-575
-
-
Ewer, M.S.1
Ewer, S.M.2
-
10
-
-
79952095377
-
Cardiotoxicity associated with targeting kinase pathways in cancer
-
Mellor H.R., Bell A.R., Valentin J.P., Roberts R.R. Cardiotoxicity associated with targeting kinase pathways in cancer. Toxicol. Sci. 2011, 120(1):14-32.
-
(2011)
Toxicol. Sci.
, vol.120
, Issue.1
, pp. 14-32
-
-
Mellor, H.R.1
Bell, A.R.2
Valentin, J.P.3
Roberts, R.R.4
-
11
-
-
84864669663
-
Timely recognition of cardiovascular toxicity by anticancer agents: a common objective of the pharmacologist, oncologist and cardiologist
-
Bonura F., Di Lisi D., Novo S., D'Alessandro N. Timely recognition of cardiovascular toxicity by anticancer agents: a common objective of the pharmacologist, oncologist and cardiologist. Cardiovasc. Toxicol. 2012, 12(2):93-107.
-
(2012)
Cardiovasc. Toxicol.
, vol.12
, Issue.2
, pp. 93-107
-
-
Bonura, F.1
Di Lisi, D.2
Novo, S.3
D'Alessandro, N.4
-
12
-
-
66549084593
-
How to optimise treatment compliance in metastatic renal cell carcinoma with targeted agents
-
Ravaud A. How to optimise treatment compliance in metastatic renal cell carcinoma with targeted agents. Ann. Oncol. 2009, 20(suppl. 1):i7-i12.
-
(2009)
Ann. Oncol.
, vol.20
, pp. i7-i12
-
-
Ravaud, A.1
-
13
-
-
84863119798
-
Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma
-
Davies M.A., Fox P.S., Papadopoulos N.E., Bedikian A.Y., Hwu W.J., Lazar A.J., Prieto V.G., Culotta K.S., Madden T.L., Xu Q., Huang S., Deng W., Ng C.S., Gupta S., Liu W., Dancey J.E., Wright J.J., Bassett R.L., Hwu P., Kim K.B. Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. Clin. Can. Res. 2012, 18(4):1120-1128.
-
(2012)
Clin. Can. Res.
, vol.18
, Issue.4
, pp. 1120-1128
-
-
Davies, M.A.1
Fox, P.S.2
Papadopoulos, N.E.3
Bedikian, A.Y.4
Hwu, W.J.5
Lazar, A.J.6
Prieto, V.G.7
Culotta, K.S.8
Madden, T.L.9
Xu, Q.10
Huang, S.11
Deng, W.12
Ng, C.S.13
Gupta, S.14
Liu, W.15
Dancey, J.E.16
Wright, J.J.17
Bassett, R.L.18
Hwu, P.19
Kim, K.B.20
more..
-
14
-
-
84858699792
-
Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma
-
Molina A.M., Feldman D.R., Voss M.H., Ginsberg M.S., Baum M.S., Brocks D.R., Fischer P.M., Trinos M.J., Patil S., Motzer R.J. Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma. Cancer 2012, 118(7):1868-1876.
-
(2012)
Cancer
, vol.118
, Issue.7
, pp. 1868-1876
-
-
Molina, A.M.1
Feldman, D.R.2
Voss, M.H.3
Ginsberg, M.S.4
Baum, M.S.5
Brocks, D.R.6
Fischer, P.M.7
Trinos, M.J.8
Patil, S.9
Motzer, R.J.10
-
15
-
-
84859874162
-
The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer
-
Shimizu T., Tolcher A.W., Papadopoulos K.P., Beeram M., Rasco D.W., Smith L.S., Gunn S., Smetzer L., Mays T.A., Kaiser B., Wick M.J., Alvarez C., Cavazos A., Mangold G.L., Patnaik A. The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer. Clin. Can. Res. 2012, 18(8):2316-2325.
-
(2012)
Clin. Can. Res.
, vol.18
, Issue.8
, pp. 2316-2325
-
-
Shimizu, T.1
Tolcher, A.W.2
Papadopoulos, K.P.3
Beeram, M.4
Rasco, D.W.5
Smith, L.S.6
Gunn, S.7
Smetzer, L.8
Mays, T.A.9
Kaiser, B.10
Wick, M.J.11
Alvarez, C.12
Cavazos, A.13
Mangold, G.L.14
Patnaik, A.15
-
16
-
-
50949132320
-
Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics
-
Chen M.H., Kerkela R., Force T. Mechanisms of cardiac dysfunction associated with tyrosine kinase inhibitor cancer therapeutics. Circulation 2008, 118:84-95.
-
(2008)
Circulation
, vol.118
, pp. 84-95
-
-
Chen, M.H.1
Kerkela, R.2
Force, T.3
-
17
-
-
84255172340
-
Predicting adverse drug events using pharmacological network models
-
Cami A., Arnold A., Manzi S., Reis B. Predicting adverse drug events using pharmacological network models. Sci. Transl. Med. 2011, 3(114):114-127.
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.114
, pp. 114-127
-
-
Cami, A.1
Arnold, A.2
Manzi, S.3
Reis, B.4
-
18
-
-
47249146126
-
Drug target identification using side-effect similarity
-
Campillos M., Kuhn M., Gavin A.C., Jensen L.J., Bork P. Drug target identification using side-effect similarity. Science 2008, 321(5886):263-266.
-
(2008)
Science
, vol.321
, Issue.5886
, pp. 263-266
-
-
Campillos, M.1
Kuhn, M.2
Gavin, A.C.3
Jensen, L.J.4
Bork, P.5
-
19
-
-
84856055845
-
Recycling side-effects into clinical markers for drug repositioning
-
Duran-Frigola M., Aloy P. Recycling side-effects into clinical markers for drug repositioning. Genome Med. 2012, 4(3).
-
(2012)
Genome Med.
, vol.4
, Issue.3
-
-
Duran-Frigola, M.1
Aloy, P.2
-
20
-
-
84875459651
-
Computational drug repositioning: from data to therapeutics
-
Hurle M.R., Yang L., Xie Q., Rajpal D.K., Sanseau P., Agarwal P. Computational drug repositioning: from data to therapeutics. Clin. Pharmacol. Therapeut. 2013, 93(4):335-341.
-
(2013)
Clin. Pharmacol. Therapeut.
, vol.93
, Issue.4
, pp. 335-341
-
-
Hurle, M.R.1
Yang, L.2
Xie, Q.3
Rajpal, D.K.4
Sanseau, P.5
Agarwal, P.6
-
21
-
-
84862510972
-
Large-scale prediction and testing of drug activity on side-effect targets
-
Lounkine E., Keiser M.J., Whitebread S., Mikhailov D., Hamon J., Jenkins J.L., Layan P., Weber E., Doak A.K., Cote S., Shoichet B.K., Urban L. Large-scale prediction and testing of drug activity on side-effect targets. Nature 2012, 486(7403):361-367.
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 361-367
-
-
Lounkine, E.1
Keiser, M.J.2
Whitebread, S.3
Mikhailov, D.4
Hamon, J.5
Jenkins, J.L.6
Layan, P.7
Weber, E.8
Doak, A.K.9
Cote, S.10
Shoichet, B.K.11
Urban, L.12
-
22
-
-
79951981575
-
Reporting of serious adverse drug reactions of targeted anticancer agents in pivotal phase III clinical trials
-
Seruga B., Sterling L., Wang L., Tannock I.F. Reporting of serious adverse drug reactions of targeted anticancer agents in pivotal phase III clinical trials. J. Clin. Oncol. 2011, 29:174-185.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 174-185
-
-
Seruga, B.1
Sterling, L.2
Wang, L.3
Tannock, I.F.4
-
23
-
-
84895421624
-
Automatic signal prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS)
-
R. Xu, Q. Wang, Automatic signal prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS), J. Biomed. Inform. (2014) 171-177.
-
(2014)
J. Biomed. Inform
, pp. 171-177
-
-
Xu, R.1
Wang, Q.2
-
24
-
-
84893172915
-
Large-scale combining signals from both biomedical literature and the FDA Adverse Event Reporting System (FAERS) to improve post-marketing drug safety signal detection
-
Xu R., Wang Q. Large-scale combining signals from both biomedical literature and the FDA Adverse Event Reporting System (FAERS) to improve post-marketing drug safety signal detection. BMC Bioinf. 2014, 15:17. 10.1186/10.1186/1471-2105-15-17.
-
(2014)
BMC Bioinf.
, vol.15
, pp. 17
-
-
Xu, R.1
Wang, Q.2
-
25
-
-
84890459951
-
Toward creation of a cancer drug toxicity knowledge base: automatically extracting cancer drug side effect relationships from literature
-
Xu R., Wang Q. Toward creation of a cancer drug toxicity knowledge base: automatically extracting cancer drug side effect relationships from literature. J. Am. Med. Inf. Assoc. 2014, 21(1):90-96.
-
(2014)
J. Am. Med. Inf. Assoc.
, vol.21
, Issue.1
, pp. 90-96
-
-
Xu, R.1
Wang, Q.2
-
26
-
-
84908037538
-
Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature
-
R. Xu, Q. Wang, Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature, J. Biomed. Inf. 51 (2014) 191-199.
-
(2014)
J. Biomed. Inf
, vol.51
, pp. 191-199
-
-
Xu, R.1
Wang, Q.2
-
27
-
-
84924491235
-
Combining automatic table classification and relationship extraction in extracting anticancer drug-side effect pairs from full-text articles
-
R. Xu, Q. Wang, Combining automatic table classification and relationship extraction in extracting anticancer drug-side effect pairs from full-text articles, J. Biomed. Inf. 53 (2015) 128-135.
-
(2015)
J. Biomed. Inf.
, vol.53
, pp. 128-135
-
-
Xu, R.1
Wang, Q.2
-
28
-
-
84882647236
-
Towards building a disease-phenotype knowledge base: extracting disease-manifestation relationship from literature
-
Xu R., Li L., Wang Q. Towards building a disease-phenotype knowledge base: extracting disease-manifestation relationship from literature. Bioinformatics 2013, 29(17):2186-2194.
-
(2013)
Bioinformatics
, vol.29
, Issue.17
, pp. 2186-2194
-
-
Xu, R.1
Li, L.2
Wang, Q.3
-
29
-
-
84899480100
-
DRiskKB: a large-scale disease-disease risk (causal) relationship knowledge base constructed from biomedical text
-
Xu R., Li L., Wang Q. dRiskKB: a large-scale disease-disease risk (causal) relationship knowledge base constructed from biomedical text. BMC Bioinf. 2014, 15:105. 10.1186/1471-2105-15-105.
-
(2014)
BMC Bioinf.
, vol.15
, pp. 105
-
-
Xu, R.1
Li, L.2
Wang, Q.3
-
30
-
-
84942412129
-
Extraction of potential adverse drug events from medical case reports
-
Gurulingappa H., Mateen Rajput A., Toldo L. Extraction of potential adverse drug events from medical case reports. J. Biomed. Semant. 2012, 3(1):15-24.
-
(2012)
J. Biomed. Semant.
, vol.3
, Issue.1
, pp. 15-24
-
-
Gurulingappa, H.1
Mateen Rajput, A.2
Toldo, L.3
-
31
-
-
0032991290
-
The medical dictionary for regulatory activities (MedDRA)
-
Brown E.G., Wood L., Wood S. The medical dictionary for regulatory activities (MedDRA). Drug Safety 1999, 20(2):109-117.
-
(1999)
Drug Safety
, vol.20
, Issue.2
, pp. 109-117
-
-
Brown, E.G.1
Wood, L.2
Wood, S.3
-
32
-
-
0345863927
-
The unified medical language system (UMLS): integrating biomedical terminology
-
Bodenreider O. The unified medical language system (UMLS): integrating biomedical terminology. Nucl. Acids Res. 2004, 32(suppl. 1):D267-D270.
-
(2004)
Nucl. Acids Res.
, vol.32
, pp. D267-D270
-
-
Bodenreider, O.1
-
33
-
-
76749092270
-
The WEKA data mining software: an update
-
Hall M., Frank E., Holmes G., Pfahringer B., Reutemann P., Witten I.H. The WEKA data mining software: an update. ACM SIGKDD Explor. Newslett. 2009, 11(1):10-18.
-
(2009)
ACM SIGKDD Explor. Newslett.
, vol.11
, Issue.1
, pp. 10-18
-
-
Hall, M.1
Frank, E.2
Holmes, G.3
Pfahringer, B.4
Reutemann, P.5
Witten, I.H.6
-
35
-
-
38549151817
-
DrugBank: a knowledgebase for drugs, drug actions and drug targets
-
Wishart D.S., Knox C., Guo A.C., Cheng D., Shrivastava S., Tzur D., Gautam B., Hassanali M. DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucl. Acids Res. 2008, 36(suppl. 1):D901-D906.
-
(2008)
Nucl. Acids Res.
, vol.36
, pp. D901-D906
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Cheng, D.4
Shrivastava, S.5
Tzur, D.6
Gautam, B.7
Hassanali, M.8
-
36
-
-
84858329412
-
Data-driven prediction of drug effects and interactions
-
125ra31
-
Tatonetti N.P., Patrick P.Y., Daneshjou R., Altman R.B. Data-driven prediction of drug effects and interactions. Sci. Transl. Med. 2012, 4(125):125ra31.
-
(2012)
Sci. Transl. Med.
, vol.4
, Issue.125
-
-
Tatonetti, N.P.1
Patrick, P.Y.2
Daneshjou, R.3
Altman, R.B.4
|