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Volumn 152, Issue 5, 2015, Pages 881-888

Rapamycin inhibits human laryngotracheal stenosis-derived fibroblast proliferation, metabolism, and function in vitro

Author keywords

collagen; fibroblasts; human; laryngotracheal stenosis; rapamycin; trachea

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL DNA; COLLAGEN TYPE 1; DIMETHYL SULFOXIDE; RAPAMYCIN; COLLAGEN; IMMUNOSUPPRESSIVE AGENT;

EID: 84930686643     PISSN: 01945998     EISSN: 10976817     Source Type: Journal    
DOI: 10.1177/0194599815573708     Document Type: Article
Times cited : (35)

References (33)
  • 1
    • 84894416727 scopus 로고    scopus 로고
    • Subglottic stenosis: A ten-year review of treatment outcomes
    • Hseu AF, Benninger MS, Haffey TM, Lorenz R. Subglottic stenosis: a ten-year review of treatment outcomes. Laryngoscope. 2014 ; 124 (3). 736-741
    • (2014) Laryngoscope , vol.124 , Issue.3 , pp. 736-741
    • Hseu, A.F.1    Benninger, M.S.2    Haffey, T.M.3    Lorenz, R.4
  • 2
    • 0021678460 scopus 로고
    • Pediatric laryngotracheal stenosis
    • Cotton RT. Pediatric laryngotracheal stenosis. J Pediatr Surg. 1984 ; 19: 699-704
    • (1984) J Pediatr Surg , vol.19 , pp. 699-704
    • Cotton, R.T.1
  • 3
    • 84902252454 scopus 로고    scopus 로고
    • Finding balance between minimally invasive surgery and laryngotracheal resection in the management of adult laryngotracheal stenosis
    • Halmos GB, Schuiringa FS, Palinko D, van der Laan TP, Dikkers FG. Finding balance between minimally invasive surgery and laryngotracheal resection in the management of adult laryngotracheal stenosis. Eur Arch Otorhinolaryngol. 2014 ; 271: 1967-1971
    • (2014) Eur Arch Otorhinolaryngol , vol.271 , pp. 1967-1971
    • Halmos, G.B.1    Schuiringa, F.S.2    Palinko, D.3    Van Der Laan, T.P.4    Dikkers, F.G.5
  • 4
  • 5
    • 79961194990 scopus 로고    scopus 로고
    • Cellular adaptive inflammation mediates airway granulation in a murine model of subglottic stenosis
    • Ghosh A, Malaisrie N, Leahy KP, et al. Cellular adaptive inflammation mediates airway granulation in a murine model of subglottic stenosis. Otolaryngol Head Neck Surg. 2011 ; 144: 927-933
    • (2011) Otolaryngol Head Neck Surg , vol.144 , pp. 927-933
    • Ghosh, A.1    Malaisrie, N.2    Leahy, K.P.3
  • 6
    • 0023069519 scopus 로고
    • Pathophysiology of subglottic tracheal stenosis in childhood
    • Minnigerode B, Richter HG. Pathophysiology of subglottic tracheal stenosis in childhood. Prog Pediatr Surg. 1987 ; 21: 1-7
    • (1987) Prog Pediatr Surg , vol.21 , pp. 1-7
    • Minnigerode, B.1    Richter, H.G.2
  • 8
    • 0018602033 scopus 로고
    • Therapy of iatrogenic subglottic stenosis: A steroid/antibiotic regimen
    • Croft CB, Zub K, Borowiecki B. Therapy of iatrogenic subglottic stenosis: a steroid/antibiotic regimen. Laryngoscope. 1979 ; 89: 482-489
    • (1979) Laryngoscope , vol.89 , pp. 482-489
    • Croft, C.B.1    Zub, K.2    Borowiecki, B.3
  • 9
    • 84875727852 scopus 로고    scopus 로고
    • Pulse steroid therapy inhibits murine subglottic granulation
    • Ghosh A, Philiponis G, Lee JY, et al. Pulse steroid therapy inhibits murine subglottic granulation. Otolaryngol Head Neck Surg. 2013 ; 148: 284-290
    • (2013) Otolaryngol Head Neck Surg , vol.148 , pp. 284-290
    • Ghosh, A.1    Philiponis, G.2    Lee, J.Y.3
  • 10
    • 8244225988 scopus 로고    scopus 로고
    • Dexamethasone treatment does not ameliorate subglottic ischemic injury in rabbits
    • Kil HK, Alberts MK, Liggitt HD, Bishop MJ. Dexamethasone treatment does not ameliorate subglottic ischemic injury in rabbits. Chest. 1997 ; 111: 1356-1360
    • (1997) Chest , vol.111 , pp. 1356-1360
    • Kil, H.K.1    Alberts, M.K.2    Liggitt, H.D.3    Bishop, M.J.4
  • 11
    • 84894263422 scopus 로고    scopus 로고
    • Dose-dependent effect of mitomycin C on human vocal fold fibroblasts
    • Li NY, Chen F, Dikkers FG, Thibeault SL. Dose-dependent effect of mitomycin C on human vocal fold fibroblasts. Head Neck. 2014 ; 36: 401-410
    • (2014) Head Neck , vol.36 , pp. 401-410
    • Li, N.Y.1    Chen, F.2    Dikkers, F.G.3    Thibeault, S.L.4
  • 12
    • 0020573349 scopus 로고
    • Antibiotics and steroids in the treatment of acquired subglottic stenosis. A canine model study
    • Supance JS. Antibiotics and steroids in the treatment of acquired subglottic stenosis. A canine model study. Ann Otol Rhinol Laryngol. 1983 ; 92: 377-382
    • (1983) Ann Otol Rhinol Laryngol , vol.92 , pp. 377-382
    • Supance, J.S.1
  • 13
    • 0028792326 scopus 로고
    • FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity
    • Cardenas ME, Heitman J. FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity. EMBO J. 1995 ; 14: 5892-5907
    • (1995) EMBO J , vol.14 , pp. 5892-5907
    • Cardenas, M.E.1    Heitman, J.2
  • 14
    • 0035165578 scopus 로고    scopus 로고
    • Rapamycin in transplantation: A review of the evidence
    • Saunders RN, Metcalfe MS, Nicholson ML. Rapamycin in transplantation: a review of the evidence. Kidney Int. 2001 ; 59: 3-16
    • (2001) Kidney Int , vol.59 , pp. 3-16
    • Saunders, R.N.1    Metcalfe, M.S.2    Nicholson, M.L.3
  • 15
    • 0028869086 scopus 로고
    • Rapamune (sirolimus, rapamycin): An overview and mechanism of action
    • Sehgal SN. Rapamune (sirolimus, rapamycin): an overview and mechanism of action. Ther Drug Monit. 1995 ; 17: 660-665
    • (1995) Ther Drug Monit , vol.17 , pp. 660-665
    • Sehgal, S.N.1
  • 16
    • 0028360374 scopus 로고
    • A mammalian protein targeted by G1-arresting rapamycin-receptor complex
    • Brown EJ, Albers MW, Shin TB, et al. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature. 1994 ; 369: 756-758
    • (1994) Nature , vol.369 , pp. 756-758
    • Brown, E.J.1    Albers, M.W.2    Shin, T.B.3
  • 17
    • 0028842194 scopus 로고
    • Prolongation of renal allograft survival in a large animal model by oral rapamycin monotherapy
    • Granger DK, Cromwell JW, Chen SC, et al. Prolongation of renal allograft survival in a large animal model by oral rapamycin monotherapy. Transplantation. 1995 ; 59: 183-186
    • (1995) Transplantation , vol.59 , pp. 183-186
    • Granger, D.K.1    Cromwell, J.W.2    Chen, S.C.3
  • 18
    • 0035806921 scopus 로고    scopus 로고
    • Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model
    • Suzuki T, Kopia G, Hayashi S, et al. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation. 2001 ; 104: 1188-1193
    • (2001) Circulation , vol.104 , pp. 1188-1193
    • Suzuki, T.1    Kopia, G.2    Hayashi, S.3
  • 19
    • 0037030658 scopus 로고    scopus 로고
    • A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization
    • Morice MC, Serruys PW, Sousa JE, et al. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med. 2002 ; 346: 1773-1780
    • (2002) N Engl J Med , vol.346 , pp. 1773-1780
    • Morice, M.C.1    Serruys, P.W.2    Sousa, J.E.3
  • 20
    • 84859060783 scopus 로고    scopus 로고
    • Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts
    • Chen G, Chen H, Wang C, et al. Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts. PLoS One. 2012 ; 7: e33626
    • (2012) PLoS One , vol.7 , pp. 33626
    • Chen, G.1    Chen, H.2    Wang, C.3
  • 21
    • 84899987036 scopus 로고    scopus 로고
    • Effects of the immunosuppressant rapamycin on the expression of human alpha2(I) collagen and matrix metalloproteinase 1 genes in scleroderma dermal fibroblasts
    • Tamaki Z, Asano Y, Kubo M, et al. Effects of the immunosuppressant rapamycin on the expression of human alpha2(I) collagen and matrix metalloproteinase 1 genes in scleroderma dermal fibroblasts. J Dermatol Sci. 2014 ; 74: 251-259
    • (2014) J Dermatol Sci , vol.74 , pp. 251-259
    • Tamaki, Z.1    Asano, Y.2    Kubo, M.3
  • 22
    • 0032738763 scopus 로고    scopus 로고
    • Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis
    • Zhu J, Wu J, Frizell E, et al. Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology. 1999 ; 117: 1198-1204
    • (1999) Gastroenterology , vol.117 , pp. 1198-1204
    • Zhu, J.1    Wu, J.2    Frizell, E.3
  • 23
    • 84887830444 scopus 로고    scopus 로고
    • Rapamycin inhibits the production of myofibroblasts and reduces corneal scarring after photorefractive keratectomy
    • Milani BY, Milani FY, Park DW, et al. Rapamycin inhibits the production of myofibroblasts and reduces corneal scarring after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 2013 ; 54: 7424-7430
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 7424-7430
    • Milani, B.Y.1    Milani, F.Y.2    Park, D.W.3
  • 24
    • 33845938244 scopus 로고    scopus 로고
    • Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?
    • Poulalhon N, Farge D, Roos N, et al. Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?. J Biol Chem. 2006 ; 281: 33045-33052
    • (2006) J Biol Chem , vol.281 , pp. 33045-33052
    • Poulalhon, N.1    Farge, D.2    Roos, N.3
  • 25
    • 0029949356 scopus 로고    scopus 로고
    • PicoGreen quantitation of DNA: Effective evaluation of samples pre- or post-PCR
    • Ahn SJ, Costa J, Emanuel JR. PicoGreen quantitation of DNA: effective evaluation of samples pre- or post-PCR. Nucleic Acids Res. 1996 ; 24: 2623-2625
    • (1996) Nucleic Acids Res , vol.24 , pp. 2623-2625
    • Ahn, S.J.1    Costa, J.2    Emanuel, J.R.3
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001 ; 25: 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 79960816393 scopus 로고    scopus 로고
    • Photoactivated composite biomaterial for soft tissue restoration in rodents and in humans
    • Hillel AT, Unterman S, Nahas Z, et al. Photoactivated composite biomaterial for soft tissue restoration in rodents and in humans. Sci Transl Med. 2011 ; 3: 93-67
    • (2011) Sci Transl Med , vol.3 , pp. 93-67
    • Hillel, A.T.1    Unterman, S.2    Nahas, Z.3
  • 29
    • 80053331862 scopus 로고    scopus 로고
    • Adaptation of microplate-based respirometry for hippocampal slices and analysis of respiratory capacity
    • Schuh RA, Clerc P, Hwang H, et al. Adaptation of microplate-based respirometry for hippocampal slices and analysis of respiratory capacity. J Neurosci Res. 2011 ; 89: 1979-1988
    • (2011) J Neurosci Res , vol.89 , pp. 1979-1988
    • Schuh, R.A.1    Clerc, P.2    Hwang, H.3
  • 30
    • 79953180902 scopus 로고    scopus 로고
    • Assessing mitochondrial dysfunction in cells
    • Brand MD, Nicholls DG. Assessing mitochondrial dysfunction in cells. Biochem J. 2011 ; 435: 297-312
    • (2011) Biochem J , vol.435 , pp. 297-312
    • Brand, M.D.1    Nicholls, D.G.2
  • 31
    • 84896698571 scopus 로고    scopus 로고
    • Loss of AMP-activated protein kinase in X-linked adrenoleukodystrophy patient-derived fibroblasts and lymphocytes
    • Singh J, Giri S. Loss of AMP-activated protein kinase in X-linked adrenoleukodystrophy patient-derived fibroblasts and lymphocytes. Biochem Biophys Res Commun. 2014 ; 445: 126-131
    • (2014) Biochem Biophys Res Commun , vol.445 , pp. 126-131
    • Singh, J.1    Giri, S.2
  • 32
    • 33846317064 scopus 로고    scopus 로고
    • Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
    • Wu M, Neilson A, Swift AL, et al. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol. 2007 ; 292: C125 - C136
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. 125-C136
    • Wu, M.1    Neilson, A.2    Swift, A.L.3
  • 33
    • 18244409638 scopus 로고    scopus 로고
    • Molecular basis of restenosis and drug-eluting stents
    • Costa MA, Simon DI. Molecular basis of restenosis and drug-eluting stents. Circulation. 2005 ; 111: 2257-2273
    • (2005) Circulation , vol.111 , pp. 2257-2273
    • Costa, M.A.1    Simon, D.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.