In vivo tracking of dendritic cell using MRI reporter gene, ferritin

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Kim, Hoe Suk ^a   Woo, Jisu ^a   Lee, Jae Hoon ^a   Joo, Hyun Jung ^a   Choi, YoonSeok ^a,b   Kim, Hyeonjin ^a,b   Moon, Woo Kyung ^a,b   Kim, Seung Ja ^c  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University Boramae Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; FERRITIN; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 2 RECEPTOR ALPHA; FERRIC FERROCYANIDE; FERROCYANIDE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL STIMULATION; CELL TRACKING; CONTROLLED STUDY; DENDRITIC CELL; FERRITIN GENE; FTH GENE; GENE; GENE EXPRESSION; GFP GENE; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANALYSIS OF VARIANCE; ANIMAL; CELL PROLIFERATION; FLOW CYTOMETRY; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; LENTIVIRINAE; LYMPH NODE; METABOLISM; PHYSIOLOGY; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

LENTIVIRUS; MUS;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; DENDRITIC CELLS; FERRITINS; FERROCYANIDES; FLOW CYTOMETRY; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LENTIVIRUS; LYMPH NODES; MAGNETIC RESONANCE IMAGING; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84930684736     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125291     Document Type: Article

References (30)

1. Lucignani G, Rescigno M. The role of molecular imaging in the development of dendritic cell-based cancer vaccines. Eur J Nucl Med Mol Imaging. 2005; 32: 725-730. PMID: 15995874
2. Ottobrini L, Martelli C, Trabattoni DL, Clerici M, Lucignani G. In vivo imaging of immune cell trafficking in cancer. Eur J Nucl Med Mol Imaging. 2011; 38: 949-68 doi: 10.1007/s00259-010-1687-7 PMID: 21170525
3. de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, Boerman OC, et al. Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 2005; 23: 1407-1413. PMID: 16258544
4. Long CM, van Laarhoven HW, Bulte JW, Levitsky HI. Magnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes. Cancer Res. 2009; 69: 3180-3187. doi: 10.1158/0008-5472.CAN-08-3691 PMID: 19276358
5. Dekaban GA, Snir J, Shrum B, de Chickera S, Willert C, Merrill M, et al. Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI. J Immunother. 2009; 32: 240-251. doi: 10.1097/CJI.0b013e318197b2a0 PMID: 19242376
6. Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, et al. Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Mol Imaging Biol. 2009; 11: 178-187. doi: 10.1007/s11307-008-0182-z PMID: 19034584
7. Cohen B, Dafni H, Meir G, Harmelin A, Neeman M. Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Neoplasia. 2005; 7: 109-117. PMID: 15802016
8. Genove G, DeMarco U, Xu H, Goins WF, Ahrens ET. A new transgene reporter for in vivo magnetic resonance imaging. Nat Med. 2005; 11: 450-454. PMID: 15778721
9. Kim HS, Cho HR, Choi SH, Woo JS, Moon WK. In vivo imaging of tumor transduced with bimodal lentiviral vector encoding human ferritin and green fluorescent protein on a 1.5T clinical magnetic resonance scanner. Cancer Res. 2010; 70: 7315-7324. doi: 10.1158/0008-5472.CAN-10-0241 PMID: 20823165
10. Choi SH, Cho HR, Kim HS, Kim YH, Kang KW, Kim H, et al. Imaging and quantification of metastatic melanoma cells in lymph nodes with a ferritin MR reporter in living mice. NMR Biomed. 2012; 25: 737-745. doi: 10.1002/nbm.1788 PMID: 22124937
11. Choi Y, Kim HS, Cho KW, Lee KM, Yi YJ, Eun SJ, et al. Noninvasive identification of viable cell populations in docetaxel-treated breast tumors using ferritin-based magnetic resonance imaging. PLoS One. 2013; 8: e52931. doi: 10.1371/journal.pone.0052931 PMID: 23301003
12. Kim HS, Joo HJ, Woo JS, Choi YS, Choi SH, Kim H, et al. In vivo magnetic resonance imaging of transgenic mice expressing human ferritin. Mol Imaging Biol. 2013; 15: 48-57. doi: 10.1007/s11307-012-0567-x PMID: 22733452
13. Baar J. Clinical applications of dendritic cell cancer vaccines. Oncologist. 1999; 4: 140-144. PMID: 10337385
14. Morse MA, Lyerly HK. Clinical applications of dendritic cell vaccines. Curr Opin Mol Ther. 2000; 2: 20-28. PMID: 11249649
15. Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature. 2007; 449: 419-426. PMID: 17898760
16. Joo HJ, Kim HS, Choi YS, Kim H, Kim SJ, Moon WK. Detection of prostaglandin E2-induced dendritic cell migration into the lymph nodes of mice using a 1.5 T clinical MR scanner. Nmr in Biomedicine. 2012; 25: 570-579. doi: 10.1002/nbm.1774 PMID: 22009917
17. Liou HL, Myers JT, Barkauskas DS, Huang AY. Intravital imaging of the mouse popliteal lymph node. J Vis Exp. 2012; 8: e3720
18. Lin KL, Fulton LM, Berginski M, West ML, Taylor NA, Moran TP, et al. Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD. Blood.2014; 123: 1604-1614. doi: 10.1182/blood-2013-09-526020 PMID: 24415540
19. Verdijk P, Scheenen TW, Lesterhuis WJ, Gambarota G, Veltien AA, Walczak P, et al. Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. Int J Cancer. 2007; 120: 978-984. PMID: 17163419
20. Reichardt W, Durr C, von Elverfeldt D, Juttner E, Gerlach UV, Yamada M, et al. Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation. J Immunol. 2008; 181: 4770-4779. PMID: 18802080
21. Briley-Saebo KC, Leboeuf M, Dickson S, Mani V, Fayad ZA, Palucka AK, et al. Longitudinal tracking of human dendritic cells in murine models using magnetic resonance imaging. Magn Reson Med. 2010; 64: 1510-1519. doi: 10.1002/mrm.22519 PMID: 20593373
22. De Vries IJ, Krooshoop DJ, Scharenborg NM, Lesterhuis WJ, Diepstra JH, Van Muijen GN, et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 2003; 63: 12-17. PMID: 12517769
23. Jonuleit H, Tuting T, Steitz J, Bruck J, Giesecke A, Steinbrink K, et al. Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity. Gene Ther. 2000; 7: 249-254. PMID: 10694802
24. VandenDriessche T, Thorrez L, Naldini L, Follenzi A, Moons L, Berneman Z, et al. Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo. Blood. 2002; 100: 813-822. PMID: 12130491
25. Lizee G, Gonzales MI, Topalian SL. Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells. Hum Gene Ther. 2004; 15: 393-404. PMID: 15053864
26. Bousso P. T-cell activation by dendritic cells in the lymph node: lessons from the movies. Nat Rev Immunol. 2008; 8: 675-684. doi: 10.1038/nri2379 PMID: 19172690
27. Wuest SC, Edwan JH, Martin JF, Han S, Perry JS, Cartagena CM et al. A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy. Nat Med. 2011; 17: 604-609. doi: 10.1038/nm.2365 PMID: 21532597
28. Boyman O, Sprent J. The role of interleukin-2 during homeostasis and activation of the immune system. Nat Rev Immunol. 2012; 12: 180-190. doi: 10.1038/nri3156 PMID: 22343569
29. Xia H, Liu H, Zhang G, Zheng Y. Phenotype and function of monocyte-derived dendritic cells from chinese rhesus macaques. Cell Mol Immunol. 2009; 6: 159-165. doi: 10.1038/cmi.2009.22 PMID: 19567198
30. Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol. 1997; 158: 2723-2730. PMID: 9058806