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Volumn 10, Issue 5, 2015, Pages

Fractionated ionizing radiation promotes epithelial-mesenchymal transition in human esophageal cancer cells through PTEN deficiency-mediated Akt activation

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SNAIL; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, HUMAN;

EID: 84930676534     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126149     Document Type: Article
Times cited : (52)

References (31)
  • 1
    • 84877122418 scopus 로고    scopus 로고
    • Multimodal treatment of esophageal cancer
    • Epub 2012/09/14 PMID: 22971784
    • Lordick F, Holscher AH, Haustermans K, Wittekind C. Multimodal treatment of esophageal cancer. Langenbecks Arch Surg. 2013; 398(2):177-87. Epub 2012/09/14. doi: 10.1007/s00423-012-1001-1 PMID: 22971784.
    • (2013) Langenbecks Arch Surg , vol.398 , Issue.2 , pp. 177-187
    • Lordick, F.1    Holscher, A.H.2    Haustermans, K.3    Wittekind, C.4
  • 2
    • 84881575374 scopus 로고    scopus 로고
    • Epidemiology of esophageal cancer in Japan and China
    • Epub 2013/05/01. DN/JST.JSTAGE/jea/JE20120162 PMID: 23629646 PubMed Central PMCID: PMC3709543
    • Lin Y, Totsuka Y, He Y, Kikuchi S, Qiao Y, Ueda J, et al. Epidemiology of esophageal cancer in Japan and China. J Epidemiol. 2013; 23(4):233-42. Epub 2013/05/01. DN/JST.JSTAGE/jea/JE20120162 [pii]. PMID: 23629646; PubMed Central PMCID: PMC3709543.
    • (2013) J Epidemiol , vol.23 , Issue.4 , pp. 233-242
    • Lin, Y.1    Totsuka, Y.2    He, Y.3    Kikuchi, S.4    Qiao, Y.5    Ueda, J.6
  • 4
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Epub 2009/06/03 PMID: 19487818; PubMed Central PMCID: PMC2689101
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009; 119 (6):1420-8. Epub 2009/06/03. doi: 10.1172/JCI3910439104 [pii]. PMID: 19487818; PubMed Central PMCID: PMC2689101.
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 5
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Epub 2009/03/06 PMID: 19262571
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer. 2009; 9(4):265-73. Epub 2009/03/06. doi: 10.1038/nrc2620nrc2620 [pii]. PMID: 19262571.
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 6
    • 84877723436 scopus 로고    scopus 로고
    • Syndecan-1 modulates beta-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiation
    • Epub 2013/01/08 PMID: 23289672
    • Hassan H, Greve B, Pavao MS, Kiesel L, Ibrahim SA, Gotte M. Syndecan-1 modulates beta-integrin-dependent and interleukin-6-dependent functions in breast cancer cell adhesion, migration, and resistance to irradiation. FEBS J. 2013; 280(10):2216-27. Epub 2013/01/08. doi: 10.1111/febs.12111 PMID: 23289672.
    • (2013) FEBS J , vol.280 , Issue.10 , pp. 2216-2227
    • Hassan, H.1    Greve, B.2    Pavao, M.S.3    Kiesel, L.4    Ibrahim, S.A.5    Gotte, M.6
  • 7
    • 79960360062 scopus 로고    scopus 로고
    • E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells
    • Epub 2011/06/18 PMID: 21680037
    • Theys J, Jutten B, Habets R, Paesmans K, Groot AJ, Lambin P, et al. E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells. Radiother Oncol. 2011; 99(3):392-7. Epub 2011/06/18. doi: 10.1016/j.radonc.2011.05.044S0167-8140(11)00237-4 [pii]. PMID: 21680037.
    • (2011) Radiother Oncol , vol.99 , Issue.3 , pp. 392-397
    • Theys, J.1    Jutten, B.2    Habets, R.3    Paesmans, K.4    Groot, A.J.5    Lambin, P.6
  • 8
    • 84876005256 scopus 로고    scopus 로고
    • Low-dose radiation-induced epithelial-mesenchymal transition through NF-kappaB in cervical cancer cells
    • Epub 2013/03/14 PMID: 23483258
    • Yan S, Wang Y, Yang Q, Li X, Kong X, Zhang N, et al. Low-dose radiation-induced epithelial-mesenchymal transition through NF-kappaB in cervical cancer cells. Int J Oncol. 2013; 42(5):1801-6. Epub 2013/03/14. doi: 10.3892/ijo.2013.1852 PMID: 23483258.
    • (2013) Int J Oncol , vol.42 , Issue.5 , pp. 1801-1806
    • Yan, S.1    Wang, Y.2    Yang, Q.3    Li, X.4    Kong, X.5    Zhang, N.6
  • 9
    • 80051798242 scopus 로고    scopus 로고
    • Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial-mesenchymal transition
    • Epub 2011/08/04 PMID: 21810413
    • Zhang X, Li X, Zhang N, Yang Q, Moran MS. Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial-mesenchymal transition. Biochem Biophys Res Commun. 2011; 412(1):188-92. Epub 2011/08/04. doi: 10.1016/j.bbrc.2011.07.074S0006-291X(11)01300-3 [pii]. PMID: 21810413.
    • (2011) Biochem Biophys Res Commun , vol.412 , Issue.1 , pp. 188-192
    • Zhang, X.1    Li, X.2    Zhang, N.3    Yang, Q.4    Moran, M.S.5
  • 10
    • 84897410473 scopus 로고    scopus 로고
    • Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3beta and repression of ZEB1
    • Epub 2014/01/29 153labinvest2013153 PMID: 24468793
    • Liu W, Huang YJ, Liu C, Yang YY, Liu H, Cui JG, et al. Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3beta and repression of ZEB1. Lab Invest. 2014; 94(4):362-70. Epub 2014/01/29. doi: 10.1038/labinvest.2013. 153labinvest2013153 [pii]. PMID: 24468793.
    • (2014) Lab Invest , vol.94 , Issue.4 , pp. 362-370
    • Liu, W.1    Huang, Y.J.2    Liu, C.3    Yang, Y.Y.4    Liu, H.5    Cui, J.G.6
  • 11
    • 51849097348 scopus 로고    scopus 로고
    • The role of PTEN signaling perturbations in cancer and in targeted therapy
    • Epub 2008/09/17 PMID: 18794882
    • Keniry M, Parsons R. The role of PTEN signaling perturbations in cancer and in targeted therapy. Oncogene. 2008; 27(41):5477-85. Epub 2008/09/17. doi: 10.1038/onc.2008.248onc2008248 [pii]. PMID: 18794882.
    • (2008) Oncogene , vol.27 , Issue.41 , pp. 5477-5485
    • Keniry, M.1    Parsons, R.2
  • 12
    • 84880506510 scopus 로고    scopus 로고
    • MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways
    • Epub 2013/05/21 PMID: 23684551
    • Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, et al. MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways. Cancer Lett. 2013; 337(2):226-36. Epub 2013/05/21. doi: 10.1016/j.canlet.2013.05.007S0304-3835(13)00376-5 [pii]. PMID: 23684551.
    • (2013) Cancer Lett , vol.337 , Issue.2 , pp. 226-236
    • Bao, L.1    Yan, Y.2    Xu, C.3    Ji, W.4    Shen, S.5    Xu, G.6
  • 13
    • 77749289244 scopus 로고    scopus 로고
    • PTEN/pAkt/p53 signaling pathway correlates with the radioresponse of non-small cell lung cancer
    • Epub 2010/03/04. PMID: 20198299
    • Jung IL, Kang HJ, Kim KC, Kim IG. PTEN/pAkt/p53 signaling pathway correlates with the radioresponse of non-small cell lung cancer. Int J Mol Med. 2010; 25(4):517-23. Epub 2010/03/04. PMID: 20198299.
    • (2010) Int J Mol Med , vol.25 , Issue.4 , pp. 517-523
    • Jung, I.L.1    Kang, H.J.2    Kim, K.C.3    Kim, I.G.4
  • 14
    • 84863116263 scopus 로고    scopus 로고
    • MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN
    • Epub 2012/02/07. 19228 PMID: 22306986
    • Qu C, Liang Z, Huang J, Zhao R, Su C, Wang S, et al. MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. Cell Cycle. 2012; 11(4). Epub 2012/02/07. 19228 [pii]. PMID: 22306986.
    • (2012) Cell Cycle , vol.11 , Issue.4
    • Qu, C.1    Liang, Z.2    Huang, J.3    Zhao, R.4    Su, C.5    Wang, S.6
  • 15
    • 79953877269 scopus 로고    scopus 로고
    • MicroRNA-221 and -222 regulate radiation sensitivity by targeting the PTEN pathway
    • Epub 2011/04/13 PMID: 21481725
    • Zhang C, Kang C, Wang P, Cao Y, Lv Z, Yu S, et al. MicroRNA-221 and -222 regulate radiation sensitivity by targeting the PTEN pathway. Int J Radiat Oncol Biol Phys. 2011; 80(1):240-8. Epub 2011/04/13. doi: 10.1016/j.ijrobp.2010.12.049S0360-3016(11)00044-7 [pii]. PMID: 21481725.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , Issue.1 , pp. 240-248
    • Zhang, C.1    Kang, C.2    Wang, P.3    Cao, Y.4    Lv, Z.5    Yu, S.6
  • 16
    • 0026543603 scopus 로고
    • Characterization of 21 newly established esophageal cancer cell lines
    • Epub 1992/01/15. PMID: 1728357
    • Shimada Y, Imamura M, Wagata T, Yamaguchi N, Tobe T. Characterization of 21 newly established esophageal cancer cell lines. Cancer. 1992; 69(2):277-84. Epub 1992/01/15. PMID: 1728357.
    • (1992) Cancer , vol.69 , Issue.2 , pp. 277-284
    • Shimada, Y.1    Imamura, M.2    Wagata, T.3    Yamaguchi, N.4    Tobe, T.5
  • 17
    • 84923089679 scopus 로고    scopus 로고
    • TGF-beta1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma
    • Epub 2014/12/30. 2940 PMID: 25544767
    • Bu F, Liu X, Li J, Chen S, Tong X, Ma C, et al. TGF-beta1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma. Oncotarget. 2014. Epub 2014/12/30. 2940 [pii]. PMID: 25544767.
    • (2014) Oncotarget
    • Bu, F.1    Liu, X.2    Li, J.3    Chen, S.4    Tong, X.5    Ma, C.6
  • 18
    • 70449635892 scopus 로고    scopus 로고
    • Reverse resistance to radiation in KYSE-150R esophageal carcinoma cell after epidermal growth factor receptor signal pathway inhibition by cetuximab
    • Epub 2009/09/12 PMID: 19744737
    • Jing Z, Gong L, Xie CY, Zhang L, Su HF, Deng X, et al. Reverse resistance to radiation in KYSE-150R esophageal carcinoma cell after epidermal growth factor receptor signal pathway inhibition by cetuximab. Radiother Oncol. 2009; 93(3):468-73. Epub 2009/09/12. doi: 10.1016/j.radonc.2009.08.008S0167-8140(09)00445-9 [pii]. PMID: 19744737.
    • (2009) Radiother Oncol , vol.93 , Issue.3 , pp. 468-473
    • Jing, Z.1    Gong, L.2    Xie, C.Y.3    Zhang, L.4    Su, H.F.5    Deng, X.6
  • 19
    • 84890852964 scopus 로고    scopus 로고
    • The Role of Snail in EMT and Tumorigenesis
    • Epub 2013/10/31. CCDT-EPUB-57089 PMID: 24168186; PubMed Central PMCID: PMC4004763
    • Wang Y, Shi J, Chai K, Ying X, Zhou BP. The Role of Snail in EMT and Tumorigenesis. Curr Cancer Drug Targets. 2013; 13(9):963-72. Epub 2013/10/31. CCDT-EPUB-57089 [pii]. PMID: 24168186; PubMed Central PMCID: PMC4004763.
    • (2013) Curr Cancer Drug Targets , vol.13 , Issue.9 , pp. 963-972
    • Wang, Y.1    Shi, J.2    Chai, K.3    Ying, X.4    Zhou, B.P.5
  • 20
    • 84858276094 scopus 로고    scopus 로고
    • Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3beta/snail signalling pathway
    • Epub 2012/02/09 PMID: 22315058; PubMed Central PMCID: PMC3304404
    • Maseki S, Ijichi K, Tanaka H, Fujii M, Hasegawa Y, Ogawa T, et al. Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3beta/snail signalling pathway. Br J Cancer. 2012; 106(6):1196-204. Epub 2012/02/09. doi: 10.1038/bjc.2012.24bjc201224 [pii]. PMID: 22315058; PubMed Central PMCID: PMC3304404.
    • (2012) Br J Cancer , vol.106 , Issue.6 , pp. 1196-1204
    • Maseki, S.1    Ijichi, K.2    Tanaka, H.3    Fujii, M.4    Hasegawa, Y.5    Ogawa, T.6
  • 21
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Epub 2004/09/28 PMID: 15448698
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, et al. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol. 2004; 6(10):931-40. Epub 2004/09/28. doi: 10.1038/ncb1173ncb1173 [pii]. PMID: 15448698.
    • (2004) Nat Cell Biol , vol.6 , Issue.10 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6
  • 22
    • 3342999485 scopus 로고    scopus 로고
    • Biologic basis for radiation oncology
    • Williston Park discussion: -5. Epub 1996/03/01. PMID: 8820451
    • Coleman CN, Stevenson MA. Biologic basis for radiation oncology. Oncology (Williston Park). 1996; 10 (3):399-411; discussion: -5. Epub 1996/03/01. PMID: 8820451.
    • (1996) Oncology , vol.10 , Issue.3 , pp. 399-411
    • Coleman, C.N.1    Stevenson, M.A.2
  • 23
    • 0030953485 scopus 로고    scopus 로고
    • Potential molecular targets for manipulating the radiation response
    • Epub 1997/02/01 PMID: 9112463
    • Maity A, Kao GD, Muschel RJ, McKenna WG. Potential molecular targets for manipulating the radiation response. Int J Radiat Oncol Biol Phys. 1997; 37(3):639-53. Epub 1997/02/01. S0360301696005986 [pii]. PMID: 9112463.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , Issue.3 , pp. 639-653
    • Maity, A.1    Kao, G.D.2    Muschel, R.J.3    McKenna, W.G.4
  • 24
    • 84901296950 scopus 로고    scopus 로고
    • Raman spectroscopic study of radioresistant oral cancer sublines established by fractionated ionizing radiation
    • Epub 2014/05/21 PMID: 24841281; PubMed Central PMCID: PMC4026477
    • Yasser M, Shaikh R, Chilakapati MK, Teni T. Raman spectroscopic study of radioresistant oral cancer sublines established by fractionated ionizing radiation. PLoS One. 2014; 9(5):e97777. Epub 2014/05/21. doi: 10.1371/journal.pone.0097777PONE-D-14-05878 [pii]. PMID: 24841281; PubMed Central PMCID: PMC4026477.
    • (2014) PLoS One , vol.9 , Issue.5
    • Yasser, M.1    Shaikh, R.2    Chilakapati, M.K.3    Teni, T.4
  • 25
    • 84887534631 scopus 로고    scopus 로고
    • HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expression
    • Epub 2014/02/12 PMID: 24513429
    • Dong Q, Sharma S, Liu H, Chen L, Gu B, Sun X, et al. HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expression. Toxicol Lett. 2013. Epub 2014/02/12. S0378-4274(13)01357-X [pii]doi: 10.1016/j.toxlet.2013.10.014 PMID: 24513429.
    • (2013) Toxicol Lett
    • Dong, Q.1    Sharma, S.2    Liu, H.3    Chen, L.4    Gu, B.5    Sun, X.6
  • 26
    • 84896319776 scopus 로고    scopus 로고
    • Identification of microRNAs involved in the radioresistance of esophageal cancer cells
    • Epub 2013/10/25 PMID: 24155113
    • Su H, Jin X, Zhang X, Xue S, Deng X, Shen L, et al. Identification of microRNAs involved in the radioresistance of esophageal cancer cells. Cell Biol Int. 2014; 38(3):318-25. Epub 2013/10/25. doi: 10.1002/cbin.10202 PMID: 24155113.
    • (2014) Cell Biol Int , vol.38 , Issue.3 , pp. 318-325
    • Su, H.1    Jin, X.2    Zhang, X.3    Xue, S.4    Deng, X.5    Shen, L.6
  • 27
    • 84865367715 scopus 로고    scopus 로고
    • Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells
    • Epub 2012/07/31 PMID: 22842564
    • Wang G, Liu L, Sharma S, Liu H, Yang W, Sun X, et al. Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells. Biochem Biophys Res Commun. 2012; 425(2):309-14. Epub 2012/07/31. doi: 10.1016/j.bbrc.2012.07.087S0006-291X(12)01394-0 [pii]. PMID: 22842564.
    • (2012) Biochem Biophys Res Commun , vol.425 , Issue.2 , pp. 309-314
    • Wang, G.1    Liu, L.2    Sharma, S.3    Liu, H.4    Yang, W.5    Sun, X.6
  • 28
    • 84878583653 scopus 로고    scopus 로고
    • Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells
    • Epub 2013/01/24 PMID: 23342249; PubMed Central PMCID: PMC3544430
    • Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, et al. Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells. Cancer Med. 2012; 1(1):5-16. Epub 2013/01/24. doi: 10.1002/cam4.4 PMID: 23342249; PubMed Central PMCID: PMC3544430.
    • (2012) Cancer Med , vol.1 , Issue.1 , pp. 5-16
    • Fan, F.1    Samuel, S.2    Evans, K.W.3    Lu, J.4    Xia, L.5    Zhou, Y.6
  • 29
    • 84901059845 scopus 로고    scopus 로고
    • EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer
    • Epub 2014/04/08 PMID: 24704156
    • Kim J, Kang HS, Lee YJ, Lee HJ, Yun J, Shin JH, et al. EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer. Cancer Lett. 2014. Epub 2014/04/08. S0304-3835(14)00194-3 [pii]doi: 10.1016/j.canlet.2014.03.025 PMID: 24704156.
    • (2014) Cancer Lett
    • Kim, J.1    Kang, H.S.2    Lee, Y.J.3    Lee, H.J.4    Yun, J.5    Shin, J.H.6
  • 30
    • 84857236729 scopus 로고    scopus 로고
    • ERK/GSK3beta/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition
    • Epub 2011/12/27 PMID: 22198183; PubMed Central PMCID: PMC3288246
    • Nagarajan D, Melo T, Deng Z, Almeida C, Zhao W. ERK/GSK3beta/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition. Free Radic Biol Med. 2012; 52(6):983-92. Epub 2011/12/27. doi: 10.1016/j.freeradbiomed.2011.11.024S0891-5849(11)01211-1 [pii]. PMID: 22198183; PubMed Central PMCID: PMC3288246.
    • (2012) Free Radic Biol Med , vol.52 , Issue.6 , pp. 983-992
    • Nagarajan, D.1    Melo, T.2    Deng, Z.3    Almeida, C.4    Zhao, W.5
  • 31
    • 79251543950 scopus 로고    scopus 로고
    • Areca nut extract upregulates vimentin by activating PI3K/AKT signaling in oral carcinoma
    • Epub 2010/12/09 PMID: 21138482
    • Tseng YH, Yang CC, Lin SC, Cheng CC, Lin SH, Liu CJ, et al. Areca nut extract upregulates vimentin by activating PI3K/AKT signaling in oral carcinoma. J Oral Pathol Med. 2011; 40(2):160-6. Epub 2010/12/09. doi: 10.1111/j.1600-0714.2010.00978.x PMID: 21138482.
    • (2011) J Oral Pathol Med , vol.40 , Issue.2 , pp. 160-166
    • Tseng, Y.H.1    Yang, C.C.2    Lin, S.C.3    Cheng, C.C.4    Lin, S.H.5    Liu, C.J.6


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