Evening and morning exhaled volatile compound patterns are different in obstructive sleep apnoea assessed with electronic nose

Sleep and Breathing

Volumn 19, Issue 1, 2015, Pages 247-253

  Kunos, Laszlo ^a   Bikov, Andras ^a   Lazar, Zsofia ^a   Korosi, Beata Zita ^a   Benedek, Palma ^b   Losonczy, Gyorgy ^a   Horvath, Ildiko ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b HEIM PÁL CHILDREN S HOSPITAL   (Hungary)

Author keywords

Breath test; Electronic nose; OSA; Sleep; Volatile organic compounds

Indexed keywords

BIOLOGICAL MARKER; VOLATILE AGENT; VOLATILE ORGANIC COMPOUND;

ACCURACY; ADULT; ARTICLE; BREATH ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRONIC NOSE; EXPIRED AIR; HUMAN; NIGHT; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SLEEP DISORDERED BREATHING; SMOKING; SNORING; SPIROMETRY; AGE; AGED; CASE CONTROL STUDY; CIRCADIAN RHYTHM; FEMALE; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; REFERENCE VALUE; SLEEP APNEA, OBSTRUCTIVE;

ADULT; AGE FACTORS; AGED; BREATH TESTS; CASE-CONTROL STUDIES; CIRCADIAN RHYTHM; ELECTRONIC NOSE; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; REFERENCE VALUES; SLEEP APNEA, OBSTRUCTIVE; VOLATILE ORGANIC COMPOUNDS;

EID: 84930617310     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-014-1003-z     Document Type: Article

References (32)

1. Ioachimescu OC, Collop NA (2012) Sleep-disordered breathing. Neurol Clin 30(4):1095–1136
2. Eastwood PR, Malhotra A, Palmer LJ, Kezirian EJ, Horner RL, Ip MS, Thurnheer R, Antic NA, Hillman DR (2010) Obstructive sleep apnoea: from pathogenesis to treatment: current controversies and future directions. Respirology 15(4):587–595
3. Li Y, Chongsuvivatwong V, Geater A, Liu A (2009) Exhaled breath condensate cytokine level as a diagnostic tool for obstructive sleep apnea syndrome. Sleep Med 10(1):95–103
4. Carpagnano GE, Kharitonov SA, Resta O, Foschino-Barbaro MP, Gramiccioni E, Barnes PJ (2003) 8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy. Chest 124(4):1386–1392
5. Petrosyan M, Perraki E, Simoes D, Koutsourelakis I, Vagiakis E, Roussos C, Gratziou C (2008) Exhaled breath markers in patients with obstructive sleep apnoea. Sleep Breath 12(3):207–215
6. Goldbart AD, Krishna J, Li RC, Serpero LD, Gozal D (2006) Inflammatory mediators in exhaled breath condensate of children with obstructive sleep apnea syndrome. Chest 130(1):143–148
7. Verhulst SL, Aerts L, Jacobs S, Schrauwen N, Haentjens D, Claes R, Vaerenberg H, Van Gaal LF, De Backer WA, Desager KN (2008) Sleep-disordered breathing, obesity, and airway inflammation in children and adolescents. Chest 134(6):1169–1175
8. Olopade CO, Christon JA, Zakkar M, Hua C, Swedler WI, Scheff PA, Rubinstein I (1997) Exhaled pentane and nitric oxide levels in patients with obstructive sleep apnea. Chest 111(6):1500–1504
9. Benedek P, Lazar Z, Bikov A, Kunos L, Katona G, Horvath I (2013) Exhaled biomarker pattern is altered in children with obstructive sleep apnoea syndrome. Int J Pediatr Otorhinolaryngol 77(8):1244–1247
10. Greulich T, Hattesohl A, Grabisch A, Koepke J, Schmid S, Noeske S, Nell C, Wencker M, Jorres RA, Vogelmeier CF, Kohler U, Koczulla AR (2013) Detection of obstructive sleep apnoea by an electronic nose. Eur Respir J 42(1):145–155
11. Bikov A, Pako J, Kovacs D, Tamasi L, Lazar Z, Rigo J, Losonczy G, Horvath I (2011) Exhaled breath volatile alterations in pregnancy assessed with electronic nose. Biomarkers 16(6):476–484
12. Bikov A, Paschalaki K, Logan-Sinclair R, Horvath I, Kharitonov SA, Barnes PJ, Usmani OS, Paredi P (2013) Standardised exhaled breath collection for the measurement of exhaled volatile organic compounds by proton transfer reaction mass spectrometry. BMC Pulm Med 13(1):43
13. Bikov A, Lazar Z, Schandl K, Antus BM, Losonczy G, Horvath I (2011) Exercise changes volatiles in exhaled breath assessed by an electronic nose. Acta Physiol Hung 98(3):321–328
14. Kovacs D, Bikov A, Losonczy G, Murakozy G, Horvath I (2013) Follow up of lung transplant recipients using an electronic nose. J Breath Res 7(1):017117
15. Kushida CA, Littner MR, Morgenthaler T, Alessi CA, Bailey D, Coleman J Jr, Friedman L, Hirshkowitz M, Kapen S, Kramer M, Lee-Chiong T, Loube DL, Owens J, Pancer JP, Wise M (2005) Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep 28(4):499–521
16. Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 8(5):597–619
17. De Maesschalck R, Jouan-Rimbaud D, Massart DL (2000) The Mahalanobis distance. Chemom Intell Lab Syst 50(1):1–18
18. Fens N, Zwinderman AH, van der Schee MP, de Nijs SB, Dijkers E, Roldaan AC, Cheung D, Bel EH, Sterk PJ (2009) Exhaled breath profiling enables discrimination of chronic obstructive pulmonary disease and asthma. Am J Respir Crit Care Med 180(11):1076–1082
19. Faul F, Erdfelder E, Buchner A, Lang AG (2009) Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods 41(4):1149–1160
20. Doleman BJ, Lewis NS (2001) Comparison of odor detection thresholds and odor discriminablities of a conducting polymer composite electronic nose versus mammalian olfaction. Sensors Actuators B Chem 72(1):41–50
21. Chavez C, Coufal CD, Carey JB, Lacey RE, Beier RC, Zahn JA (2004) The impact of supplemental dietary methionine sources on volatile compound concentrations in broiler excreta. Poult Sci 83(6):901–910
22. Maciejak TR, Kukawska-Tarnawska B, Tyszkiewicz J, Tysykiewicz S (2002) Multi-sensor odour detection and measurement of polluted food. Pol J Food Nutr Sci 12(53):45–48
23. D'Amico A, Pennazza G, Santonico M, Martinelli E, Roscioni C, Galluccio G, Paolesse R, Di Natale C (2010) An investigation on electronic nose diagnosis of lung cancer. Lung Cancer 68(2):170–176
24. Dragonieri S, Annema JT, Schot R, van der Schee MP, Spanevello A, Carratu P, Resta O, Rabe KF, Sterk PJ (2009) An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD. Lung Cancer 64(2):166–170
25. Machado RF, Laskowski D, Deffenderfer O, Burch T, Zheng S, Mazzone PJ, Mekhail T, Jennings C, Stoller JK, Pyle J, Duncan J, Dweik RA, Erzurum SC (2005) Detection of lung cancer by sensor array analyses of exhaled breath. Am J Respir Crit Care Med 171(11):1286–1291
26. Dragonieri S, Schot R, Mertens BJ, Le Cessie S, Gauw SA, Spanevello A, Resta O, Willard NP, Vink TJ, Rabe KF, Bel EH, Sterk PJ (2007) An electronic nose in the discrimination of patients with asthma and controls. J Allergy Clin Immunol 120(4):856–862
27. Hu FB, Willett WC, Colditz GA, Ascherio A, Speizer FE, Rosner B, Hennekens CH, Stampfer MJ (1999) Prospective study of snoring and risk of hypertension in women. Am J Epidemiol 150(8):806–816
28. Phillips M, Greenberg J, Cataneo RN (2000) Effect of age on the profile of alkanes in normal human breath. Free Radic Res 33(1):57–63
29. Lechner M, Moser B, Niederseer D, Karlseder A, Holzknecht B, Fuchs M, Colvin S, Tilg H, Rieder J (2006) Gender and age specific differences in exhaled isoprene levels. Respir Physiol Neurobiol 154(3):478–483
30. Cheng ZJ, Warwick G, Yates DH, Thomas PS (2009) An electronic nose in the discrimination of breath from smokers and non-smokers: a model for toxin exposure. J Breath Res 3(3):036003
31. Dalton P, Gelperin A, Preti G (2004) Volatile metabolic monitoring of glycemic status in diabetes using electronic olfaction. Diabetes Technol Ther 6(4):534–544
32. Timms C, Thomas PS, Yates DH (2012) Detection of gastro-oesophageal reflux disease (GORD) in patients with obstructive lung disease using exhaled breath profiling. J Breath Res 6(1):016003