Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Choi, Bo Young ^a   Kim, Jin Hee ^a   Kho, A Ra ^a   Kim, In Yeol ^a   Lee, Song Hee ^a   Lee, Bo Eun ^a   Choi, Eunhi ^a   Sohn, Min ^b   Stevenson, Mackenzie ^d   Chung, Tae Nyoung ^c   Kauppinen, Tiina M ^d   Suh, Sang Won ^a  

^a Hallym University   (South Korea)

^b Inha University   (South Korea)

^c CHA University   (South Korea)

^d UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Apocynin; Experimental autoimmune encephalomyelitis; Microglia; Multiple sclerosis; NADPH oxidase; Reactive oxygen species

Indexed keywords

APOCYNIN; CD20 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA; ACETOPHENONE DERIVATIVE; CYTOKINE; ENZYME INHIBITOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DISEASE COURSE; ENZYME ACTIVATION; ENZYME INHIBITION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; HISTOPATHOLOGY; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MICROGLIA; MONONUCLEAR CELL; MOUSE; MULTIPLE SCLEROSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WHITE MATTER INJURY; ANIMAL; BLOOD TESTIS BARRIER; BRAIN; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LEUKOENCEPHALOPATHIES; MALE; METABOLISM; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; SEVERITY OF ILLNESS INDEX; SPINAL CORD;

ACETOPHENONES; ANIMALS; ANIMALS, NEWBORN; BLOOD-TESTIS BARRIER; BRAIN; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME INHIBITORS; FEMALE; LEUKOENCEPHALOPATHIES; MALE; MICE; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NADPH OXIDASE; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES; SEVERITY OF ILLNESS INDEX; SPINAL CORD;

EID: 84930615437     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0325-5     Document Type: Article

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