Predicted Role of NAD Utilization in the Control of Circadian Rhythms during DNA Damage Response

PLoS Computational Biology

Volumn 11, Issue 5, 2015, Pages

  Luna, Augustin ^a,b   McFadden, Geoffrey B ^c   Aladjem, Mirit I ^a   Kohn, Kurt W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BOSTON UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; BIOINFORMATICS; BIOSYNTHESIS; CLOCKS; DNA; REDOX REACTIONS;

BIOLOGICAL PROCESS; CIRCADIAN CLOCK; CIRCADIAN RHYTHMS; DNA DAMAGE RESPONSE; DNA DAMAGES; EXTERNAL STRESS; GENOTOXIC STRESS; NICOTINAMIDE ADENINE DINUCLEOTIDES; PHASE-SHIFTING; POSSIBLE MECHANISMS;

PROTEINS;

ADENOSINE TRIPHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; SIRTUIN 1; CIRCADIAN RHYTHM SIGNALING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK;

ARTICLE; BIOSYNTHESIS; CIRCADIAN RHYTHM; COMPUTER MODEL; DNA DAMAGE; KINETIC PARAMETERS; METABOLISM; NONHUMAN; OSCILLATION; OXIDATION REDUCTION REACTION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIMULATION; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; COMPUTER SIMULATION; GENETICS; HUMAN; IDEOMOTOR APRAXIA; PHYSIOLOGY;

ANIMALS; APRAXIA, IDEOMOTOR; ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SIGNALING PEPTIDES AND PROTEINS; CLOCK PROTEINS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DNA DAMAGE; HUMANS; MODELS, BIOLOGICAL; NAD; PERIOD CIRCADIAN PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; SIRTUIN 1;

EID: 84930608392     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004144     Document Type: Article

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