An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

PLoS Computational Biology

Volumn 11, Issue 5, 2015, Pages

  Keller, Daniel ^a   Babai, Norbert ^a   Kochubey, Olexiy ^a   Han, Yunyun ^a   Markram, Henry ^a   Schürmann, Felix ^a   Schneggenburger, Ralf ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GEOMETRY; PROBABILITY; STOCHASTIC SYSTEMS;

ACTIVE ZONE; CA 2+; EXCLUSION ZONES; GEOMETRICAL CONSTRAINTS; HIGH SLOPES; LARGE MODELS; MULTIPLE CHANNELS; RELEASE CONTROL; SPATIAL ARRANGEMENTS; STOCHASTICS;

TRANSMITTERS;

CALCIUM CHANNEL; EGTAZIC ACID; CALCIUM CHELATING AGENT; EGTA ACETOXYMETHYL ESTER;

ADULT; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL VACUOLE; CENTRAL NERVOUS SYSTEM; CHANNEL GATING; CONTROLLED STUDY; ELECTRON MICROSCOPY; MOUSE; NONHUMAN; PRESYNAPTIC NERVE; PROBABILITY; STOCHASTIC MODEL; SYNAPSE; ANALOGS AND DERIVATIVES; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; C57BL MOUSE; COMPUTER SIMULATION; IN VITRO STUDY; KINETICS; MARKOV CHAIN; METABOLISM; SYNAPSE VESICLE; TRAPEZOID BODY;

ANIMALIA;

ANIMALS; CALCIUM CHANNELS; CALCIUM CHELATING AGENTS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; EGTAZIC ACID; IN VITRO TECHNIQUES; KINETICS; MICE; MICE, INBRED C57BL; MODELS, NEUROLOGICAL; STOCHASTIC PROCESSES; SYNAPSES; SYNAPTIC VESICLES; TRAPEZOID BODY;

EID: 84930607352     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004253     Document Type: Article

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