Tryptophan to Glycine mutation in the position 116 leads to protein aggregation and decreases the stability of the LITAF protein

Journal of Biomolecular Structure and Dynamics

Volumn 33, Issue 8, 2015, Pages 1695-1709

  Kumar, Chundi Vinay ^a   Swetha, Rayapadi G ^a   Ramaiah, Sudha ^a   Anbarasu, Anand ^a  

^a VIT UNIVERSITY   (India)

Author keywords

Charcot Marie Tooth disease; lipopolysaccharide induced TNF factor protein; molecular dynamics simulations; protein aggregation; SNP analysis

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCINE; LIPOPOLYSACCHARIDE INDUCED TUMOR NECROSIS FACTOR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; TRYPTOPHAN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CODON; LITAF PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL MIGRATION; CHROMOSOME 16; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; GENE FUNCTION; GENE LOCATION; GENE MAPPING; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; LITAF GENE; LOSS OF FUNCTION MUTATION; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; CHEMICAL STRUCTURE; CHEMISTRY; CODON; GENETIC PREDISPOSITION; GENETICS; HYDROGEN BOND; MUTATION; PROTEIN CONFORMATION; PROTEINOSIS; REPRODUCIBILITY; STRUCTURE ACTIVITY RELATION;

CODON; GENETIC PREDISPOSITION TO DISEASE; GLYCINE; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN CONFORMATION; PROTEIN STABILITY; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRYPTOPHAN;

EID: 84930572258     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2014.968211     Document Type: Article

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