Phosphodiesterase 7 inhibition induces dopaminergic neurogenesis in hemiparkinsonian rats

Stem Cells Translational Medicine

Volumn 4, Issue 6, 2015, Pages 564-575

  Morales Garcia, Jose A ^a,b   Alonso Gil, Sandra ^a,b   Gil, Carmen ^c   Martinez, Ana ^c   Santos, Angel ^b,d   Perez Castillo, Ana ^a,b  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Dopaminergic differentiation; Neurogenesis; Parkinson s disease; Phosphodiesterase 7

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; NUCLEAR RECEPTOR RELATED FACTOR 1; OXIDOPAMINE; PHOSPHODIESTERASE VII; PHOSPHODIESTERASE VII INHIBITOR; S 14; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; PHOSPHODIESTERASE INHIBITOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; ENZYME INHIBITION; GENE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; MESENCEPHALON; NERVE REGENERATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PARKINSONISM; PDE7 A GENE; PDE7 B GENE; RAT; SUBSTANTIA NIGRA PARS COMPACTA; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PARKINSONIAN DISORDERS; PATHOLOGY; WISTAR RAT;

RATTUS; RODENTIA;

ANIMALS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 7; DOPAMINERGIC NEURONS; MALE; NEUROGENESIS; NEUROPROTECTIVE AGENTS; PARKINSONIAN DISORDERS; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, WISTAR;

EID: 84930517283     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0277     Document Type: Article

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