Vitamin E improves biochemical indices associated with symptoms of atopic dermatitis-like inflammation in NC/Nga mice

Journal of Nutritional Science and Vitaminology

Volumn 58, Issue 3, 2012, Pages 161-168

  Hayashi, Daisuke ^a   Sugaya, Hotaka ^a   Ohkoshi, Takayuki ^a   Sekizawa, Kaori ^a   Takatsu, Hirokatsu ^a   Shinkai, Tadashi ^b   Urano, Shiro ^a  

^a SHIBAURA INSTITUTE OF TECHNOLOGY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Atopic dermatitis; Biochemical indices; Cytokine; Oxidative stress; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; CATALASE; CYCLOOXYGENASE 2; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PICRYL CHLORIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ATOPIC DERMATITIS; BLOOD SAMPLING; DISEASE SEVERITY; ENZYME ACTIVITY; MOUSE; MOUSE STRAIN; NC NGA MOUSE; NONHUMAN; SKIN;

EID: 84930481370     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.58.161     Document Type: Article

References (25)

1. Thepen T, Langeveld-Wildschut EG, Bihari IC, van Wichen DF, van Reijse FC. 1996. Biphasic response against aeroallergen in atopic dermatitis showing a swichfrom an initial Th2 response to a Th1 response in situ. J Allergy Clin Immunol 97: 828-837.
2. Grewe M, Bruijinzeel-Koomen C, Schpf E, Thepen T, Langeveld-Wildschut AG. 1998. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis. Immunol Today 19: 359-361.
3. Homey B, Steinhoff M, Ruzicka T, Leung DY. 2006. Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 118: 178-189.
4. Ahn JY, Choi SE, Jeong MS, Park KH, Moon NJ, Joo SS, Lee CS, Choi YW, Li K, Lee MK, Lee MVV, Seo SJ. 2010. Effect of taxifolin glycoside on atopic dermatitis-like skin lesions in NC/Nga mice. Phytother Res 24: 1071-1077.
5. Omata N, Tsukahara H, Ito S, Ohshima Y, Yasutomi M, Yamada A, Jiang M, Hiraoka M, Nambu M, Deguchi Y, Mayumi M. 2001. Increased oxidative stress in childhood atopic dermatitis. Life Sci 69: 223-228.
6. Tsukahara H, Shibata R, Ohshima Y, Todoroki Y, Sato S, Ohta N, Hiraoka M, Yoshida A, Nishima S, Mayumi M. 2003. Oxidative stress and altered antioxidant defenses in children with acute exacerbation of atopic dermatitis. Life Sci 72: 2509-2516.
7. Aly DG, Shahin RS. 2010. Oxidative stress in lichen planus. Acta Dermatoven APA 19: 3-11.
8. Bradley JR. 2008. TNF-mediated inflammatory disease. J Pathol 214: 149-160.
9. Hayden MS, Ghosh S. 2008. Shared principles in NF-_B signaling. Cell 132: 344-362.
10. Ghosh S, Karin M. 2002. Missing pieces in the NF-_B puzzle. Cell 109: S81-S96.
11. Traber MG, Packer L. 1995. Vitamin E: beyond antioxidant function. Am J Clin Nutr 62: 1501S-1509S.
12. Nazrun AS, Norazlina M, Norliza M, Nirwana, SI. 2012. The anti-inflammatory role of vitamin E in prevention of osteoporosis. Adv Pharmacol Sci 2012, 142702.
13. Ohkawa H, Onishi N, Yagi K. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358.
14. Aebi H. 1984. Catalase in vitro. Methods Enzymol 105: 121-126.
15. Flohe L, Gunzler WA. 1984. Assays glutathione peroxidase. Methods Enzymol 105: 114-121.
16. Uchida K, Kanematsu M, Sakai K, Matsuda T, Hattori N, Mizuno Y, Suzuki D, Miyata T, Noguchi N, Niki E, Osawa T. 1998. Protein-bound acrolein: Potential markers for oxidative stress. Proc Natl Acad Sci USA 95: 4882-4887.
17. Kapun AP, Salobir J, Levart A, Kotnik T, Svete AN. 2012. Oxidative stress markers in canine atopic dermatitis. Res Vet Sci 92: 469-470.
18. Matsuda H, Watanabe N, Geba GP, Sperl J, Tsudzuki M, Hiroi J, Matsumoto M, Ushio H, Saito S, Askenase PW, Ra C. 1997. Development of atopic dermatitis-like lesion with IgE hyperproduction in NC/Nga mice. Int Immunol 9: 461-466.
19. Leung, DYM. 2000. Atopic dermatitis: new insights and opportunities for therapeutic intervention. J Allergy Clin Immunol 32: 860-876.
20. Oomizu S, Onishi N, Suzuki H, Ueda K, Mochizuki M, Morimoto K, Kawamoto S, Ono K, Kameyoshi Y, Hide M. 2006. Oral administration of pulverized Konjac glucomannan prevents the increase of plasma immunoglobulin E and immunoglobulin G levels induced by the injection of syngeneic keratinocyte extracts in BALB/c mice. Clin Exp Allergy 36: 102-110.
21. Wu D, Hayek MG, Meydani S. 2001. Vitamin E and macrophage cyclooxygenase regulation in the aged. J Nutr 131: 382S-388S.
22. Marble DJ, Gordon KB, Nickoloff BJ. 2007. Targeting TNF_ rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation. J Dermatol Sci 48: 87-101.
23. Wang H, Peters T, Kess D, Sindrilaru A, Oreshkova T, Van Rooijen N, Stratis A, Renkl AC, Sunderkotter C, Wlaschek M, Scharffetter-Kochanek K. 2006. Activated macrophages are essential in a murine model for T cellmediated chronic psoriasiform skin inflammation. J Clin Invest 116: 2105-2114.
24. Stratis A, Pasparakis M, Rupec RA, Markur D, Hartmann K, Scharffetter-Kochanek K, Peters T, Van Rooijen N, Krieg T, Haase I. 2006. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J Clin Invest 116: 2094-2104.
25. Tanaka A, Muto S, Jung K, Itai A, Matsuda H. 2007. Topical application with a new NF-_B inhibitor improves atopic dermatitis in NC/NgaTnd mice. J Invest Dermatol 127: 855-863.