-
1
-
-
77956793432
-
Molecular genetics of prostate cancer: New prospects for old challenges
-
Shen MM, Abate-Shen C,. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev 2010; 24: 1967-2000.
-
(2010)
Genes Dev
, vol.24
, pp. 1967-2000
-
-
Shen, M.M.1
Abate-Shen, C.2
-
2
-
-
77956615624
-
Primitive origins of prostate cancer: In vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells
-
Goldstein AS, Stoyanova T, Witte ON,. Primitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells. Mol Oncol 2010; 4: 385-396.
-
(2010)
Mol Oncol
, vol.4
, pp. 385-396
-
-
Goldstein, A.S.1
Stoyanova, T.2
Witte, O.N.3
-
3
-
-
0032849766
-
Androgen receptor expression of proliferating basal and luminal cells in adult murine ventral prostate
-
Mirosevich J, Bentel J, Zeps N, et al., Androgen receptor expression of proliferating basal and luminal cells in adult murine ventral prostate. J Endocrinol 1999; 162: 341-350.
-
(1999)
J Endocrinol
, vol.162
, pp. 341-350
-
-
Mirosevich, J.1
Bentel, J.2
Zeps, N.3
-
4
-
-
0023501125
-
Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement
-
English HF, Santen RJ, Isaacs JT,. Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement. Prostate 1987; 11: 229-242.
-
(1987)
Prostate
, vol.11
, pp. 229-242
-
-
English, H.F.1
Santen, R.J.2
Isaacs, J.T.3
-
5
-
-
0026464555
-
Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer
-
Verhagen APM, Ramaekers FCS, Aalders TW, et al., Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer. Cancer Res 1992; 52: 6182-6187.
-
(1992)
Cancer Res
, vol.52
, pp. 6182-6187
-
-
Verhagen, A.P.M.1
Ramaekers, F.C.S.2
Aalders, T.W.3
-
6
-
-
0027972462
-
Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate: Simultaneous demonstration of cell-specific epithelial markers
-
Bonkhoff H, Stein U, Remberger K,. Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate: simultaneous demonstration of cell-specific epithelial markers. Hum Pathol 1994; 25: 42-46.
-
(1994)
Hum Pathol
, vol.25
, pp. 42-46
-
-
Bonkhoff, H.1
Stein, U.2
Remberger, K.3
-
7
-
-
57649140583
-
Generation of a prostate from a single adult stem cell
-
Leong KG, Wang BE, Johnson L, et al., Generation of a prostate from a single adult stem cell. Nature 2008; 456: 804-808.
-
(2008)
Nature
, vol.456
, pp. 804-808
-
-
Leong, K.G.1
Wang, B.E.2
Johnson, L.3
-
8
-
-
33846065145
-
Isolation and functional characterization of murine prostate stem cells
-
Lawson DA, Xin L, Lukacs RU, et al., Isolation and functional characterization of murine prostate stem cells. Proc Natl Acad Sci USA 2007; 104: 181-186.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 181-186
-
-
Lawson, D.A.1
Xin, L.2
Lukacs, R.U.3
-
9
-
-
58549086529
-
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics
-
Goldstein AS, Lawson DA, Cheng D, et al., Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. Proc Natl Acad Sci USA 2008; 105: 20882-20887.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20882-20887
-
-
Goldstein, A.S.1
Lawson, D.A.2
Cheng, D.3
-
10
-
-
72249113369
-
high stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model
-
high stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model. Cancer Res 2009; 69: 8555-8562.
-
(2009)
Cancer Res
, vol.69
, pp. 8555-8562
-
-
Mulholland, D.J.1
Xin, L.2
Morim, A.3
-
11
-
-
84874517173
-
Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice
-
Lu T-L, Huang Y-F, You L-R, et al., Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice. Am J Pathol 2013; 182: 975-991.
-
(2013)
Am J Pathol
, vol.182
, pp. 975-991
-
-
Lu, T.-L.1
Huang, Y.-F.2
You, L.-R.3
-
12
-
-
84874645057
-
Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity
-
Wang ZA, Mitrofanova A, Bergren SK, et al., Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity. Nat Cell Biol 2013; 15: 274-283.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 274-283
-
-
Wang, Z.A.1
Mitrofanova, A.2
Bergren, S.K.3
-
13
-
-
84863078902
-
Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation
-
Choi N, Zhang B, Zhang L, et al., Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. Cancer Cell 2012; 21: 253-265.
-
(2012)
Cancer Cell
, vol.21
, pp. 253-265
-
-
Choi, N.1
Zhang, B.2
Zhang, L.3
-
14
-
-
80054987127
-
Regenerated luminal epithelial cells are derived from pre-existing luminal epithelial cells in adult mouse prostate
-
Liu J, Pascal LE, Isharwal S, et al., Regenerated luminal epithelial cells are derived from pre-existing luminal epithelial cells in adult mouse prostate. Mol Endocrinol 2011; 25: 1849-1857.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1849-1857
-
-
Liu, J.1
Pascal, L.E.2
Isharwal, S.3
-
15
-
-
70349438989
-
A luminal epithelial stem cell that is a cell of origin for prostate cancer
-
Wang X, Kruithof-de Julio M, Economides KD, et al., A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009; 461: 495-500.
-
(2009)
Nature
, vol.461
, pp. 495-500
-
-
Wang, X.1
Kruithof-De Julio, M.2
Economides, K.D.3
-
16
-
-
84922550917
-
Luminal cells are favored as the cell of origin for prostate cancer
-
Wang Zhu A, Toivanen R, Bergren Sarah K, et al., Luminal cells are favored as the cell of origin for prostate cancer. Cell Rep 2014; 8: 1339-1346.
-
(2014)
Cell Rep
, vol.8
, pp. 1339-1346
-
-
Wang Zhu, A.1
Toivanen, R.2
Bergren Sarah, K.3
-
17
-
-
80052473223
-
Clonal architecture of human prostatic epithelium in benign and malignant conditions
-
Gaisa NT, Graham TA, McDonald SAC, et al., Clonal architecture of human prostatic epithelium in benign and malignant conditions. J Pathol 2011; 225: 172-180.
-
(2011)
J Pathol
, vol.225
, pp. 172-180
-
-
Gaisa, N.T.1
Graham, T.A.2
McDonald, S.A.C.3
-
18
-
-
80052449394
-
In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells
-
Blackwood JK, Williamson SC, Greaves LC, et al., In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells. J Pathol 2011; 225: 181-188.
-
(2011)
J Pathol
, vol.225
, pp. 181-188
-
-
Blackwood, J.K.1
Williamson, S.C.2
Greaves, L.C.3
-
19
-
-
84863138365
-
Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression
-
Drake JM, Graham NA, Stoyanova T, et al., Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. Proc Natl Acad Sci USA 2012; 109: 1643-1648.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1643-1648
-
-
Drake, J.M.1
Graham, N.A.2
Stoyanova, T.3
-
20
-
-
77249178726
-
Basal epithelial stem cells are efficient targets for prostate cancer initiation
-
Lawson DA, Zong Y, Memarzadeh S, et al., Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci USA 2010; 107: 2610-2615.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2610-2615
-
-
Lawson, D.A.1
Zong, Y.2
Memarzadeh, S.3
-
21
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein AS, Huang J, Guo C, et al., Identification of a cell of origin for human prostate cancer. Science 2010; 329: 568-571.
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
-
22
-
-
33646739524
-
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
-
Xin L, Teitell MA, Lawson DA, et al., Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor. Proc Natl Acad Sci USA 2006; 103: 7789-7794.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7789-7794
-
-
Xin, L.1
Teitell, M.A.2
Lawson, D.A.3
-
23
-
-
84890275857
-
Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells
-
Stoyanova T, Cooper AR, Drake JM, et al., Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells. Proc Natl Acad Sci USA 2013; 110: 20111-20116.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 20111-20116
-
-
Stoyanova, T.1
Cooper, A.R.2
Drake, J.M.3
-
24
-
-
0347087570
-
β-Catenin signaling in prostate cancer: An early perspective
-
Chesire DR, Isaacs WB,. β-Catenin signaling in prostate cancer: an early perspective. Endocr Relat Cancer 2003; 10: 537-560.
-
(2003)
Endocr Relat Cancer
, vol.10
, pp. 537-560
-
-
Chesire, D.R.1
Isaacs, W.B.2
-
25
-
-
0038339044
-
Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation
-
Bierie B, Nozawa M, Renou JP, et al., Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation. Oncogene 2003; 22: 3875-3887.
-
(2003)
Oncogene
, vol.22
, pp. 3875-3887
-
-
Bierie, B.1
Nozawa, M.2
Renou, J.P.3
-
26
-
-
0037071903
-
Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia
-
Gounari F, Signoretti S, Bronson R, et al., Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia. Oncogene 2002; 21: 4099-4107.
-
(2002)
Oncogene
, vol.21
, pp. 4099-4107
-
-
Gounari, F.1
Signoretti, S.2
Bronson, R.3
-
27
-
-
70350167612
-
Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment
-
Nagamani SC, Zhang F, Shchelochkov OA, et al., Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment. J Med Genet 2009; 46: 825-833.
-
(2009)
J Med Genet
, vol.46
, pp. 825-833
-
-
Nagamani, S.C.1
Zhang, F.2
Shchelochkov, O.A.3
-
28
-
-
84873486287
-
β-Catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma
-
Francis JC, Thomsen MK, Taketo MM, et al., β-Catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma. PLoS Genet 2013; 9: e1003180.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003180
-
-
Francis, J.C.1
Thomsen, M.K.2
Taketo, M.M.3
-
29
-
-
0035034603
-
Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
-
Brault V, Moore R, Kutsch S, et al., Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 2001; 128: 1253-1264.
-
(2001)
Development
, vol.128
, pp. 1253-1264
-
-
Brault, V.1
Moore, R.2
Kutsch, S.3
-
30
-
-
35548932872
-
A global double-fluorescent Cre reporter mouse
-
Muzumdar MD, Tasic B, Miyamichi K, et al., A global double-fluorescent Cre reporter mouse. Genesis 2007; 45: 593-605.
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
-
31
-
-
33947164297
-
GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen
-
Moriyama A, Kii I, Sunabori T, et al., GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen. Genesis 2007; 45: 90-100.
-
(2007)
Genesis
, vol.45
, pp. 90-100
-
-
Moriyama, A.1
Kii, I.2
Sunabori, T.3
-
32
-
-
77954069855
-
Isolation, cultivation and characterization of adult murine prostate stem cells
-
Lukacs RU, Goldstein AS, Lawson DA, et al., Isolation, cultivation and characterization of adult murine prostate stem cells. Nat Protoc 2010; 5: 702-713.
-
(2010)
Nat Protoc
, vol.5
, pp. 702-713
-
-
Lukacs, R.U.1
Goldstein, A.S.2
Lawson, D.A.3
-
33
-
-
84911398801
-
Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome
-
Yu YR, You LR, Yan YT, et al., Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome. Hum Mol Genet 2014; 23: 5579-5596.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 5579-5596
-
-
Yu, Y.R.1
You, L.R.2
Yan, Y.T.3
-
34
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al., The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
35
-
-
84863650416
-
EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice
-
Morel AP, Hinkal GW, Thomas C, et al., EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. PLoS Genet 2012; 8: e1002723.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002723
-
-
Morel, A.P.1
Hinkal, G.W.2
Thomas, C.3
-
36
-
-
78649669021
-
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
-
Lukacs RU, Memarzadeh S, Wu H, et al., Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell 2010; 7: 682-693.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 682-693
-
-
Lukacs, R.U.1
Memarzadeh, S.2
Wu, H.3
-
37
-
-
57149090285
-
The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells
-
Vander Griend DJ, Karthaus WL, Dalrymple S, et al., The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells. Cancer Res 2008; 68: 9703-9711.
-
(2008)
Cancer Res
, vol.68
, pp. 9703-9711
-
-
Vander Griend, D.J.1
Karthaus, W.L.2
Dalrymple, S.3
-
38
-
-
77953472807
-
CD133, Trop-2 and α2β1 integrin surface receptors as markers of putative human prostate cancer stem cells
-
Trerotola M, Rathore S, Goel HL, et al., CD133, Trop-2 and α2β1 integrin surface receptors as markers of putative human prostate cancer stem cells. Am J Transl Res 2010; 2: 135-144.
-
(2010)
Am J Transl Res
, vol.2
, pp. 135-144
-
-
Trerotola, M.1
Rathore, S.2
Goel, H.L.3
-
39
-
-
18844424692
-
Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue
-
Burger PE, Xiong X, Coetzee S, et al., Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue. Proc Natl Acad Sci USA 2005; 102: 7180-7185.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7180-7185
-
-
Burger, P.E.1
Xiong, X.2
Coetzee, S.3
-
40
-
-
18744377702
-
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
-
Xin L, Lawson DA, Witte ON,. The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis. Proc Natl Acad Sci USA 2005; 102: 6942-6947.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6942-6947
-
-
Xin, L.1
Lawson, D.A.2
Witte, O.N.3
-
41
-
-
67649948804
-
WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
-
Bisson I, Prowse DM,. WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics. Cell Res 2009; 19: 683-697.
-
(2009)
Cell Res
, vol.19
, pp. 683-697
-
-
Bisson, I.1
Prowse, D.M.2
-
42
-
-
84872733084
-
Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells
-
ra5.
-
Carreras Puigvert J, von Stechow L, Siddappa R, et al., Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells. Sci Signal 2013; 6: ra5.
-
(2013)
Sci Signal
, vol.6
-
-
Carreras Puigvert, J.1
Von Stechow, L.2
Siddappa, R.3
-
43
-
-
29344467436
-
Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element
-
Magee JA, Chang LW, Stormo GD, et al., Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element. Endocrinology 2006; 147: 590-598.
-
(2006)
Endocrinology
, vol.147
, pp. 590-598
-
-
Magee, J.A.1
Chang, L.W.2
Stormo, G.D.3
-
44
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
Mostaghel EA, Page ST, Lin DW, et al., Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 2007; 67: 5033-5041.
-
(2007)
Cancer Res
, vol.67
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
-
45
-
-
79958764107
-
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
-
Mulholland DJ, Tran LM, Li Y, et al., Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 2011; 19: 792-804.
-
(2011)
Cancer Cell
, vol.19
, pp. 792-804
-
-
Mulholland, D.J.1
Tran, L.M.2
Li, Y.3
-
46
-
-
79954502628
-
Neural stem cells are increased after loss of β-catenin, but neural progenitors undergo cell death
-
Holowacz T, Huelsken J, Dufort D, et al., Neural stem cells are increased after loss of β-catenin, but neural progenitors undergo cell death. Eur J Neurosci 2011; 33: 1366-1375.
-
(2011)
Eur J Neurosci
, vol.33
, pp. 1366-1375
-
-
Holowacz, T.1
Huelsken, J.2
Dufort, D.3
-
47
-
-
1642499734
-
β-Catenin is dispensable for hematopoiesis and lymphopoiesis
-
Cobas M, Wilson A, Ernst B, et al., β-Catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med 2004; 199: 221-229.
-
(2004)
J Exp Med
, vol.199
, pp. 221-229
-
-
Cobas, M.1
Wilson, A.2
Ernst, B.3
-
48
-
-
36649002031
-
Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo
-
Zhao C, Blum J, Chen A, et al., Loss of β-catenin impairs the renewal of normal and CML stem cells in vivo. Cancer Cell 2007; 12: 528-541.
-
(2007)
Cancer Cell
, vol.12
, pp. 528-541
-
-
Zhao, C.1
Blum, J.2
Chen, A.3
-
49
-
-
38049105637
-
Long-term, multilineage hematopoiesis occurs in the combined absence of β-catenin and γ-catenin
-
Jeannet Gg, Scheller M, Scarpellino Lo, et al., Long-term, multilineage hematopoiesis occurs in the combined absence of β-catenin and γ-catenin. Blood 2008; 111: 142-149.
-
(2008)
Blood
, vol.111
, pp. 142-149
-
-
Gg, J.1
Scheller, M.2
Scarpellino, L.3
-
50
-
-
77950287628
-
The Wnt/β-catenin pathway is required for the development of leukemia stem cells in AML
-
Wang Y, Krivtsov AV, Sinha AU, et al., The Wnt/β-catenin pathway is required for the development of leukemia stem cells in AML. Science 2010; 327: 1650-1653.
-
(2010)
Science
, vol.327
, pp. 1650-1653
-
-
Wang, Y.1
Krivtsov, A.V.2
Sinha, A.U.3
-
51
-
-
41649089525
-
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
-
Malanchi I, Peinado H, Kassen D, et al., Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling. Nature 2008; 452: 650-653.
-
(2008)
Nature
, vol.452
, pp. 650-653
-
-
Malanchi, I.1
Peinado, H.2
Kassen, D.3
|