RSV P-protein impairs extrinsic apoptosis pathway in a macrophage-like cell line persistently infected with respiratory syncytial virus

Virus Research

Volumn 204, Issue , 2015, Pages 82-87

  Nakamura Lopez, Yuko ^a,c   Villegas Sepúlveda, Nicolas ^b   Gómez, Beatriz ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c Centro Ambulatorio para la Prevención y Atención del SIDA y otras ITS 7a   (Mexico)

Author keywords

Extrinsic apoptotic pathway; RSV P protein; RSV persistence

Indexed keywords

CASPASE 8; CASPASE 9; GLYCINE DEHYDROGENASE (DECARBOXYLATING); STAUROSPORINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; VIRUS PROTEIN; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN RESPIRATORY SYNCYTIAL VIRUS; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; CELL LINE; CELL SURVIVAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PATHOGENICITY; PHYSIOLOGY; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SIGNAL TRANSDUCTION; UPREGULATION; VIROLOGY;

RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

APOPTOSIS; CASPASE 8; CASPASE 9; CELL LINE; CELL SURVIVAL; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; SIGNAL TRANSDUCTION; STAUROSPORINE; UP-REGULATION;

EID: 84930454610     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2015.04.018     Document Type: Article

References (37)

1. Altschul S.F., Madden T.L., Schaffer A.A., Zhang J., Zhang Z., Miller W., Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997, 25(17):3389-3402.
2. Best S.M. Viral subversion of apoptotic enzymes: escape from death row. Annu. Rev. Microbiol. 2008, 62:171-192.
3. Bitko V., Shulyayeva O., Mazumder B., Musiyenko A., Ramaswamy M., Look D.C., Barik S. Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growth. J. Virol. 2007, 81(4):1786-1795.
4. Choudhary M.L., Wadhwa B.S., Jadhav S.M., Chadha M.S. Complete genome sequences of two human respiratory syncytial virus genotype A strains from India, RSV-A/NIV1114046/11 and RSV-A/NIV1114073/11. Genome Announc. 2013, 1(4).
5. Collins P.L., Fearns R., Graham B.S. Respiratory syncytial virus: virology, reverse genetics, and pathogenesis of disease. Curr. Top. Microbiol. Immunol. 2013, 372:3-38.
6. Doctor K.S., Reed J.C., Godzik A., Bourne P.E. The apoptosis database. Cell Death Differ. 2003, 10(6):621-633.
7. Eckardt-Michel J., Lorek M., Baxmann D., Grunwald T., Keil G.M., Zimmer G. The fusion protein of respiratory syncytial virus triggers p53-dependent apoptosis. J. Virol. 2008, 82(7):3236-3249.
8. Ekert P.G., Silke J., Vaux D.L. Caspase inhibitors. Cell Death Differ. 1999, 6(11):1081-1086.
9. Falsey A.R., Walsh E.E. Respiratory syncytial virus infection in adults. Clin. Microbiol. Rev. 2000, 13(3):371-384.
10. Feldman A.S., He Y., Moore M.L., Hershenson M.B., Hartert T.V. Toward primary prevention of asthma: reviewing the evidence for early-life respiratory viral infections as modifiable risk factors to prevent childhood asthma. Am. J. Respir. Crit. Care Med. 2014.
11. Fuentes S., Tran K.C., Luthra P., Teng M.N., He B. Function of the respiratory syncytial virus small hydrophobic protein. J. Virol. 2007, 81(15):8361-8366.
12. Fuentes-Prior P., Salvesen G.S. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 2004, 384(Pt 2):201-232.
13. Gaddy D.F., Lyles D.S. Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathways. J. Virol. 2005, 79(7):4170-4179.
14. Galluzzi L., Brenner C., Morselli E., Touat Z., Kroemer G. Viral control of mitochondrial apoptosis. PLoS Pathog. 2008, 4(5):e1000018.
15. Gaona J., Santiago-Olivares C., Ortega E., Gomez B. Respiratory syncytial virus persistence in macrophages upregulates Fcgamma receptors expression. Viruses 2014, 6(2):624-639.
16. Gaur U., Aggarwal B.B. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem. Pharmacol. 2003, 66(8):1403-1408.
17. Hall C.B., Simoes E.A., Anderson L.J. Clinical and epidemiologic features of respiratory syncytial virus. Curr. Top. Microbiol. Immunol. 2013, 372:39-57.
18. Hay S., Kannourakis G. A time to kill: viral manipulation of the cell death program. J. General Virol. 2002, 83(Pt 7):1547-1564.
19. Hilleman M.R. Strategies and mechanisms for host and pathogen survival in acute and persistent viral infections. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(Suppl. 2):14560-14566.
20. Jordan M., Wurm F. Transfection of adherent and suspended cells by calcium phosphate. Methods 2004, 33(2):136-143.
21. Kaminskyy V., Zhivotovsky B. To kill or be killed: how viruses interact with the cell death machinery. J. Intern. Med. 2010, 267(5):473-482.
22. Kane M., Golovkina T. Common threads in persistent viral infections. J. Virol. 2010, 84(9):4116-4123.
23. Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 1972, 26(4):239-257.
24. Krueger A., Schmitz I., Baumann S., Krammer P.H., Kirchhoff S. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J. Biol. Chem. 2001, 276(23):20633-20640.
25. Martinez I., Lombardia L., Herranz C., Garcia-Barreno B., Dominguez O., Melero J.A. Cultures of HEp-2 cells persistently infected by human respiratory syncytial virus differ in chemokine expression and resistance to apoptosis as compared to lytic infections of the same cell type. Virology 2009, 388(1):31-41.
26. Nakamura-Lopez Y., Sarmiento-Silva R.E., Moran-Andrade J., Gomez-Garcia B. Staurosporine-induced apoptosis in P388D1 macrophages involves both extrinsic and intrinsic pathways. Cell Biol. Int. 2009, 33(9):1026-1031.
27. Nakamura-Lopez Y., Villegas-Sepulveda N., Sarmiento-Silva R.E., Gomez B. Intrinsic apoptotic pathway is subverted in mouse macrophages persistently infected by RSV. Virus Res. 2011, 158(1-2):98-107.
28. Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 2004, 149(1-3):19-23.
29. Piedimonte G. Respiratory syncytial virus and asthma: speed-dating or long-term relationship?. Curr. Opin. Pediatr. 2013, 25(3):344-349.
30. Proenca-Modena J.L., Buzatto G.P., Paula F.E., Saturno T.H., Delcaro L.S., Prates M.C., Tamashiro E., Valera F.C., Arruda E., Anselmo-Lima W.T. Respiratory viruses are continuously detected in children with chronic tonsillitis throughout the year. Int. J. Pediatr. Otorhinolaryngol. 2014, 78(10):1655-1661.
31. Sarmiento R.E., Tirado R., Gomez B. Characteristics of a respiratory syncytial virus persistently infected macrophage-like culture. Virus Res. 2002, 84(1-2):45-58.
32. Spann K.M., Tran K.C., Chi B., Rabin R.L., Collins P.L. Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages (corrected). J. Virol. 2004, 78(8):4363-4369.
33. van den Berg E., van Woensel J.B., Bem R.A. Apoptosis in pneumovirus infection. Viruses 2013, 5(1):406-422.
34. van den Berg E., van Woensel J.B., Bos A.P., Bem R.A., Altemeier W.A., Gill S.E., Martin T.R., Matute-Bello G. Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 2011, 301(4):L451-L460.
35. van Raam B.J., Salvesen G.S. Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate. Biochim. Biophys. Acta 2012, 1824(1):113-122.
36. Wilson R.L., Fuentes S.M., Wang P., Taddeo E.C., Klatt A., Henderson A.J., He B. Function of small hydrophobic proteins of paramyxovirus. J. Virol. 2006, 80(4):1700-1709.
37. Zheng C., Kabaleeswaran V., Wang Y., Cheng G., Wu H. Crystal structures of the TRAF2:cIAP2 and the TRAF1:TRAF2:cIAP2 complexes: affinity, specificity, and regulation. Mol. Cell 2010, 38(1):101-113.