-
2
-
-
0002458132
-
The effect of retarded growth upon the length of life span and upon the ultimate body size
-
McCay C, Crowell MF and Maynard L. The effect of retarded growth upon the length of life span and upon the ultimate body size. J nutr. 1935; 10:63.
-
(1935)
J nutr.
, vol.10
, pp. 63
-
-
McCay, C.1
Crowell, M.F.2
Maynard, L.3
-
4
-
-
50649099122
-
Aging and survival: the genetics of life span extension by dietary restriction
-
Mair W and Dillin A. Aging and survival: the genetics of life span extension by dietary restriction. Annu Rev Biochem. 2008; 77:727-754.
-
(2008)
Annu Rev Biochem.
, vol.77
, pp. 727-754
-
-
Mair, W.1
Dillin, A.2
-
5
-
-
84887212584
-
Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C
-
Mair W, Panowski SH, Shaw RJ and Dillin A. Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans. PLoS One. 2009; 4:e4535.
-
(2009)
elegans. PLoS One.
, vol.4
-
-
Mair, W.1
Panowski, S.H.2
Shaw, R.J.3
Dillin, A.4
-
6
-
-
0032573178
-
The genetics of caloric restriction in Caenorhabditis elegans
-
Lakowski B and Hekimi S. The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 1998; 95:13091-13096.
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 13091-13096
-
-
Lakowski, B.1
Hekimi, S.2
-
7
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C elegans
-
Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP and Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol. 2007; 17:1646-1656.
-
(2007)
Curr Biol.
, vol.17
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
Villen, J.4
Hoang, K.5
Blanchard, D.6
Gygi, S.P.7
Brunet, A.8
-
8
-
-
33751250243
-
Lifespan extension in Caenorhabditis elegans by complete removal of food
-
Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, Fields S, Kennedy BK and Kaeberlein M. Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell. 2006; 5:487-494.
-
(2006)
Aging Cell.
, vol.5
, pp. 487-494
-
-
Kaeberlein, T.L.1
Smith, E.D.2
Tsuchiya, M.3
Welton, K.L.4
Thomas, J.H.5
Fields, S.6
Kennedy, B.K.7
Kaeberlein, M.8
-
9
-
-
84905041609
-
A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans
-
Chamoli M, Singh A, Malik Y and Mukhopadhyay A. A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans. Aging Cell. 2014; DOI: 10.1111/acel.12218.
-
(2014)
Aging Cell.
-
-
Chamoli, M.1
Singh, A.2
Malik, Y.3
Mukhopadhyay, A.4
-
10
-
-
84884661996
-
Deletion of microRNA-80 activates dietary restriction to extend C elegans healthspan and lifespan
-
Vora M, Shah M, Ostafi S, Onken B, Xue J, Ni JZ, Gu S and Driscoll M. Deletion of microRNA-80 activates dietary restriction to extend C. elegans healthspan and lifespan. PLoS Genet. 2013; 9:e1003737.
-
(2013)
PLoS Genet.
, vol.9
-
-
Vora, M.1
Shah, M.2
Ostafi, S.3
Onken, B.4
Xue, J.5
Ni, J.Z.6
Gu, S.7
Driscoll, M.8
-
11
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C
-
Panowski SH, Wolff S, Aguilaniu H, Durieux J and Dillin A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature. 2007; 447:550-555.
-
(2007)
elegans. Nature.
, vol.447
, pp. 550-555
-
-
Panowski, S.H.1
Wolff, S.2
Aguilaniu, H.3
Durieux, J.4
Dillin, A.5
-
12
-
-
84883805211
-
The role of miRNAs in regulating gene expression networks
-
Gurtan AM and Sharp PA. The role of miRNAs in regulating gene expression networks. Journal of molecular biology. 2013; 425:3582-3600.
-
(2013)
Journal of molecular biology.
, vol.425
, pp. 3582-3600
-
-
Gurtan, A.M.1
Sharp, P.A.2
-
14
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297.
-
(2004)
Cell.
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
15
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP and Bartel DP. The impact of microRNAs on protein output. Nature. 2008; 455:64-71.
-
(2008)
Nature.
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
16
-
-
29144505309
-
The widespread impact of mammalian MicroRNAs on mRNA repression and evolution
-
Farh KK, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge CB and Bartel DP. The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science (New York, NY). 2005; 310:1817-1821.
-
(2005)
Science (New York, NY).
, vol.310
, pp. 1817-1821
-
-
Farh, K.K.1
Grimson, A.2
Jan, C.3
Lewis, B.P.4
Johnston, W.K.5
Lim, L.P.6
Burge, C.B.7
Bartel, D.P.8
-
17
-
-
84885131782
-
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise
-
Siciliano V, Garzilli I, Fracassi C, Criscuolo S, Ventre S and di Bernardo D. MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise. Nature communications. 2013; 4:2364.
-
(2013)
Nature communications.
, vol.4
, pp. 2364
-
-
Siciliano, V.1
Garzilli, I.2
Fracassi, C.3
Criscuolo, S.4
Ventre, S.5
di Bernardo, D.6
-
18
-
-
84887120736
-
Dampening of expression oscillations by synchronous regulation of a microRNA and its target
-
Kim Dh, Grun D and van Oudenaarden A. Dampening of expression oscillations by synchronous regulation of a microRNA and its target. Nature genetics. 2013; 45:1337-1344.
-
(2013)
Nature genetics.
, vol.45
, pp. 1337-1344
-
-
Kim, Dh.1
Grun, D.2
van Oudenaarden, A.3
-
20
-
-
84900873500
-
MicroRNA-based single-gene circuits buffer protein synthesis rates against perturbations
-
Strovas TJ, Rosenberg AB, Kuypers BE, Muscat RA and Seelig G. MicroRNA-based single-gene circuits buffer protein synthesis rates against perturbations. ACS synthetic biology. 2014; 3:324-331.
-
(2014)
ACS synthetic biology.
, vol.3
, pp. 324-331
-
-
Strovas, T.J.1
Rosenberg, A.B.2
Kuypers, B.E.3
Muscat, R.A.4
Seelig, G.5
-
21
-
-
84899871935
-
MicroRNAs and their roles in developmental canalization
-
Posadas DM and Carthew RW. MicroRNAs and their roles in developmental canalization. Curr Opin Genet Dev. 2014; 27C:1-6.
-
(2014)
Curr Opin Genet Dev.
, vol.27C
, pp. 1-6
-
-
Posadas, D.M.1
Carthew, R.W.2
-
22
-
-
84984765621
-
Canalization of development by microRNAs
-
Hornstein E and Shomron N. Canalization of development by microRNAs. Nat Genet. 2006; 38 Suppl:S20-24.
-
(2006)
Nat Genet.
, vol.38
, pp. S20-S24
-
-
Hornstein, E.1
Shomron, N.2
-
24
-
-
84875884141
-
Ageing and the small, non-coding RNA world
-
Kato M and Slack FJ. Ageing and the small, non-coding RNA world. Ageing Res Rev. 2012.
-
(2012)
Ageing Res Rev
-
-
Kato, M.1
Slack, F.J.2
-
25
-
-
84858142662
-
MicroRNAs and their roles in aging
-
Smith-Vikos T and Slack FJ. MicroRNAs and their roles in aging. J Cell Sci. 2012; 125:7-17.
-
(2012)
J Cell Sci.
, vol.125
, pp. 7-17
-
-
Smith-Vikos, T.1
Slack, F.J.2
-
26
-
-
84883750693
-
MicroRNAs and the genetic network in aging
-
Sachi I and Frank S. MicroRNAs and the genetic network in aging. Journal of molecular biology. 2013; 425:3601-3608.
-
(2013)
Journal of molecular biology.
, vol.425
, pp. 3601-3608
-
-
Sachi, I.1
Frank, S.2
-
27
-
-
33744485559
-
Modulated microRNA expression during adult lifespan in Caenorhabditis elegans
-
Ibanez-Ventoso C, Yang M, Guo S, Robins H, Padgett RW and Driscoll M. Modulated microRNA expression during adult lifespan in Caenorhabditis elegans. Aging cell. 2006; 5:235-246.
-
(2006)
Aging cell.
, vol.5
, pp. 235-246
-
-
Ibanez-Ventoso, C.1
Yang, M.2
Guo, S.3
Robins, H.4
Padgett, R.W.5
Driscoll, M.6
-
28
-
-
68649126873
-
MicroRNAs in C. elegans Aging: Molecular Insurance for Robustness?
-
Ibanez-Ventoso C and Driscoll M. MicroRNAs in C. elegans Aging: Molecular Insurance for Robustness? Curr Genomics. 2009; 10:144-153.
-
(2009)
Curr Genomics.
, vol.10
, pp. 144-153
-
-
Ibanez-Ventoso, C.1
Driscoll, M.2
-
29
-
-
79551614016
-
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C
-
Niu W, Lu ZJ, Zhong M, Sarov M, Murray JI, Brdlik CM, Janette J, Chen C, Alves P, Preston E, Slightham C, Jiang L, Hyman AA, et al. Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome research. 2011; 21:245-254.
-
(2011)
elegans. Genome research.
, vol.21
, pp. 245-254
-
-
Niu, W.1
Lu, Z.J.2
Zhong, M.3
Sarov, M.4
Murray, J.I.5
Brdlik, C.M.6
Janette, J.7
Chen, C.8
Alves, P.9
Preston, E.10
Slightham, C.11
Jiang, L.12
Hyman, A.A.13
-
30
-
-
77649225979
-
Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response
-
Zhong M, Niu W, Lu ZJ, Sarov M, Murray JI, Janette J, Raha D, Sheaffer KL, Lam HY, Preston E, Slightham C, Hillier LW, Brock T, et al. Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response. PLoS Genet. 2010; 6:e1000848.
-
(2010)
PLoS Genet.
, vol.6
-
-
Zhong, M.1
Niu, W.2
Lu, Z.J.3
Sarov, M.4
Murray, J.I.5
Janette, J.6
Raha, D.7
Sheaffer, K.L.8
Lam, H.Y.9
Preston, E.10
Slightham, C.11
Hillier, L.W.12
Brock, T.13
-
31
-
-
80053210307
-
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C
-
Kato M, Chen X, Inukai S, Zhao H and Slack FJ. Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. Rna. 2011; 17:1804-1820.
-
(2011)
elegans. Rna.
, vol.17
, pp. 1804-1820
-
-
Kato, M.1
Chen, X.2
Inukai, S.3
Zhao, H.4
Slack, F.J.5
-
32
-
-
77950200010
-
The genetics of ageing
-
Kenyon CJ. The genetics of ageing. Nature. 2010; 464:504-512.
-
(2010)
Nature.
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
33
-
-
0027771804
-
A C elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993; 366:461-464.
-
(1993)
Nature.
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
34
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C elegans developmental timing
-
Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G and Mello CC. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell. 2001; 106:23-34.
-
(2001)
Cell.
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
Baillie, D.L.7
Fire, A.8
Ruvkun, G.9
Mello, C.C.10
-
35
-
-
0037423919
-
The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C elegans
-
Shen K and Bargmann CI. The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans. Cell. 2003; 112:619-630.
-
(2003)
Cell.
, vol.112
, pp. 619-630
-
-
Shen, K.1
Bargmann, C.I.2
-
36
-
-
0033885209
-
A C elegans patched gene, ptc-1, functions in germ-line cytokinesis
-
Kuwabara PE, Lee MH, Schedl T and Jefferis GS. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Genes & development. 2000; 14:1933-1944.
-
(2000)
Genes & development.
, vol.14
, pp. 1933-1944
-
-
Kuwabara, P.E.1
Lee, M.H.2
Schedl, T.3
Jefferis, G.S.4
-
37
-
-
0030762006
-
Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants
-
Baum PD and Garriga G. Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants. Neuron. 1997; 19:51-62.
-
(1997)
Neuron.
, vol.19
, pp. 51-62
-
-
Baum, P.D.1
Garriga, G.2
-
38
-
-
0034980967
-
Germline and developmental roles of the nuclear transport factor importin alpha3 in C elegans
-
Geles KG and Adam SA. Germline and developmental roles of the nuclear transport factor importin alpha3 in C. elegans. Development (Cambridge, England). 2001; 128:1817-1830.
-
(2001)
Development (Cambridge, England).
, vol.128
, pp. 1817-1830
-
-
Geles, K.G.1
Adam, S.A.2
-
39
-
-
84866110768
-
Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans
-
Yuan Y, Kadiyala CS, Ching TT, Hakimi P, Saha S, Xu H, Yuan C, Mullangi V, Wang L, Fivenson E, Hanson RW, Ewing R, Hsu AL, et al. Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans. J Biol Chem. 2012; 287:31414-31426.
-
(2012)
J Biol Chem.
, vol.287
, pp. 31414-31426
-
-
Yuan, Y.1
Kadiyala, C.S.2
Ching, T.T.3
Hakimi, P.4
Saha, S.5
Xu, H.6
Yuan, C.7
Mullangi, V.8
Wang, L.9
Fivenson, E.10
Hanson, R.W.11
Ewing, R.12
Hsu, A.L.13
-
40
-
-
34249079154
-
Network motifs: theory and experimental approaches
-
Alon U. Network motifs: theory and experimental approaches. Nature reviews Genetics. 2007; 8:450.
-
(2007)
Nature reviews Genetics.
, vol.8
, pp. 450
-
-
Alon, U.1
-
41
-
-
84877309346
-
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
-
Riedel C, Dowen R, Lourenco G, Kirienko N, Heimbucher T, West J, Bowman S, Kingston R, Dillin A, Asara J and Ruvkun G. DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nature cell biology. 2013; 15:491.
-
(2013)
Nature cell biology.
, vol.15
, pp. 491
-
-
Riedel, C.1
Dowen, R.2
Lourenco, G.3
Kirienko, N.4
Heimbucher, T.5
West, J.6
Bowman, S.7
Kingston, R.8
Dillin, A.9
Asara, J.10
Ruvkun, G.11
-
42
-
-
80053312481
-
Autophagy and lipid metabolism coordinately modulate life span in germline-less C elegans
-
Lapierre LR, Gelino S, Melendez A and Hansen M. Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol. 2011; 21:1507-1514.
-
(2011)
Curr Biol.
, vol.21
, pp. 1507-1514
-
-
Lapierre, L.R.1
Gelino, S.2
Melendez, A.3
Hansen, M.4
-
43
-
-
34249819336
-
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
-
Tsang J, Zhu J and van Oudenaarden A. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Molecular cell. 2007; 26:753-767.
-
(2007)
Molecular cell.
, vol.26
, pp. 753-767
-
-
Tsang, J.1
Zhu, J.2
van Oudenaarden, A.3
-
44
-
-
84873121957
-
A fasting-responsive signaling pathway that extends life span in C elegans
-
Uno M, Honjoh S, Matsuda M, Hoshikawa H, Kishimoto S, Yamamoto T, Ebisuya M, Yamamoto T, Matsumoto K and Nishida E. A fasting-responsive signaling pathway that extends life span in C. elegans. Cell reports. 2013; 3:79-91.
-
(2013)
Cell reports.
, vol.3
, pp. 79-91
-
-
Uno, M.1
Honjoh, S.2
Matsuda, M.3
Hoshikawa, H.4
Kishimoto, S.5
Yamamoto, T.6
Ebisuya, M.7
Yamamoto, T.8
Matsumoto, K.9
Nishida, E.10
-
45
-
-
77956645160
-
Ubiquitin ligases join the field of dietary restriction in C.elegans
-
Lucanic M and Kapahi P. Ubiquitin ligases join the field of dietary restriction in C.elegans. Aging. 2009; 1:751-752.
-
(2009)
Aging.
, vol.1
, pp. 751-752
-
-
Lucanic, M.1
Kapahi, P.2
-
46
-
-
67651004289
-
A conserved ubiquitination pathway determines longevity in response to diet restriction
-
Carrano AC, Liu Z, Dillin A and Hunter T. A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature. 2009; 460:396-399.
-
(2009)
Nature.
, vol.460
, pp. 396-399
-
-
Carrano, A.C.1
Liu, Z.2
Dillin, A.3
Hunter, T.4
-
47
-
-
78049353347
-
Regulation of protein turnover by longevity pathways
-
Vellai T and Takacs-Vellai K. Regulation of protein turnover by longevity pathways. Adv Exp Med Biol. 2010; 694:69-80.
-
(2010)
Adv Exp Med Biol.
, vol.694
, pp. 69-80
-
-
Vellai, T.1
Takacs-Vellai, K.2
-
48
-
-
66349105688
-
The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans
-
Choe KP, Przybysz AJ and Strange K. The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans. Mol Cell Biol. 2009; 29:2704-2715.
-
(2009)
Mol Cell Biol.
, vol.29
, pp. 2704-2715
-
-
Choe, K.P.1
Przybysz, A.J.2
Strange, K.3
-
49
-
-
34249891333
-
Two neurons mediate dietrestriction- induced longevity in C elegans
-
Bishop NA and Guarente L. Two neurons mediate dietrestriction- induced longevity in C. elegans. Nature. 2007; 447:545-549.
-
(2007)
Nature.
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
50
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M and Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS genetics. 2008; 4.
-
(2008)
PLoS genetics
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
51
-
-
84908179554
-
MicroRNAs Mediate Dietary-Restriction- Induced Longevity through PHA-4/FOXA and SKN-1/Nrf Transcription Factors
-
Smith-Vikos T, de Lencastre A, Inukai S, Shlomchik M, Holtrup B and Slack FJ. MicroRNAs Mediate Dietary-Restriction- Induced Longevity through PHA-4/FOXA and SKN-1/Nrf Transcription Factors. Curr Biol. 2014; 24:2238-2246.
-
(2014)
Curr Biol.
, vol.24
, pp. 2238-2246
-
-
Smith-Vikos, T.1
de Lencastre, A.2
Inukai, S.3
Shlomchik, M.4
Holtrup, B.5
Slack, F.J.6
|