Albumin-associated free fatty acids induce macropinocytosis in podocytes

Journal of Clinical Investigation

Volumn 125, Issue 6, 2015, Pages 2307-2316

  Chung, Jun Jae ^a   Huber, Tobias B ^a,b,c   Gödel, Markus ^a   Jarad, George ^d   Hartleben, Björn ^a   Kwoh, Christopher ^d   Keil, Alexander ^a   Karpitskiy, Aleksey ^a   Hu, Jiancheng ^a   Huh, Christine J ^e   Cella, Marina ^a   Gross, Richard W ^a   Miner, Jeffrey H ^d   Shaw, Andrey S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d Renal Division   (United States)

^e Department of Developmental Biology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALBUMIN; ANGIOPOIETIN; ANGIOPOIETIN LIKE 4; AQUAPORIN; CREATININE; DOCOSAHEXAENOIC ACID; FATTY ACID; FFAR2 PROTEIN; FFAR3 PROTEIN; G PROTEIN COUPLED RECEPTOR 40; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; ICOSAPENTAENOIC ACID; ICOSATRIENOIC ACID; IMMUNOGLOBULIN G; OLEIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN CDC42; RAC1 PROTEIN; UNCLASSIFIED DRUG; ALBUMINOID; ANTINEOPLASTIC ANTIBIOTIC; DOXORUBICIN; FAT INTAKE; NEUROPEPTIDE; RAC1 PROTEIN, MOUSE;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ALBUMIN BLOOD LEVEL; ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENDOCYTOSIS; ENZYME INHIBITION; ENZYME REGULATION; EXTRACELLULAR FLUID; FATTY ACID BLOOD LEVEL; GENE OVEREXPRESSION; GENE SILENCING; GLOMERULAR FILTRATION BARRIER; GLOMERULUS BASEMENT MEMBRANE; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIPID DIET; MALE; MOUSE; NEPHROTIC SYNDROME; NONHUMAN; PINOCYTOSIS; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; PROTEINURIA; SIGNAL TRANSDUCTION; ADVERSE EFFECTS; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; FAT INTAKE; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHARMACOLOGY; TRANSFORMED CELL LINE;

ALBUMINS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TRANSFORMED; DIETARY FATS; DOXORUBICIN; FATTY ACIDS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEPHROTIC SYNDROME; NEUROPEPTIDES; PINOCYTOSIS; PODOCYTES; PROTEINURIA; RAC1 GTP-BINDING PROTEIN;

EID: 84930394651     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI79641     Document Type: Article

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