CDCA5 overexpression is an indicator of poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder

American Journal of Translational Research

Volumn 7, Issue 4, 2015, Pages 710-722

  Chang, I Wei ^a,b   Lin, Victor Chia Hsiang ^a,b   He, Hong Lin ^b   Hsu, Chao Tien ^b   Li, Ching Chia ^c,d,e   Wu, Wen Jeng ^c,e,f   Huang, Chun Nung ^c,e   Wu, Ting Feng ^g   Li, Chien Feng ^g,h,i  

^a I SHOU UNIVERSITY   (Taiwan)

^b E DA HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d KAOHSIUNG MUNICIPAL TA TUNG HOSPITAL   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^f KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

^g SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^h CHI MEI MEDICAL CENTER   (Taiwan)

ⁱ NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

CDCA5; Cell division cycle associated 5; Upper tract; Urinary bladder; Urothelial carcinoma

Indexed keywords

CYCLIN DEPENDENT KINASE 5; MESSENGER RNA;

ADULT; AGED; APOPTOSIS; ARTICLE; BLADDER CARCINOMA; CANCER PROGNOSIS; CANCER SPECIFIC SURVIVAL; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; POLYMERASE CHAIN REACTION; QUANTIGENE ASSAY; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TRANSCRIPTION REGULATION; TRANSITIONAL CELL CARCINOMA; URINARY TRACT CARCINOMA; WESTERN BLOTTING;

EID: 84930391458     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Rouprêt M, Babjuk M, Compérat E, Zigeuner R, Sylvester R, Burger M, Cowan N, Böhle A, Van Rhijn BW, Kaasinen E, Palou J, Shariat SF; European Association of Urology. European guidelines on upper tract urothelial carcinomas: 2013 update. Eur Urol 2011; 59: 584-594.
2. McLaughlin JK, Silverman DT, Hsing AW, Ross RK, Schoenberg JB, Yu MC, Stemhagen A, Lynch CF, Blot WJ, Fraumeni JF Jr. Cigarette smoking and cancers of the renal pelvis and ureter. Cancer Res 1992; 52: 254-257.
3. Pommer W, Bronder E, Klimpel A, Helmert U, Greiser E, Molzahn M. Urothelial cancer at different tumour sites: Role of smoking and habitual intake of analgesics and laxatives. Results of the berlin urothelial cancer study. Nephrol Dial Transplant 1999; 14: 2892-2897.
4. Shinka T, Miyai M, Sawada Y, Inagaki T, Okawa T. Factors affecting the occurrence of urothelial tumors in dye workers exposed to aromatic amines. Int J Urol 1995; 2: 243-248.
5. Dragicevic D, Djokic M, Pekmezovic T, Micic S, Hadzi-Djokic J, Vuksanovic A, Simic T. Survival of patients with transitional cell carcinoma of the ureter and renal pelvis in balkan endemic nephropathy and non-endemic areas of serbia. BJU Int 2007; 99: 1357-1362.
6. Debelle FD, Vanherweghem JL, Nortier JL. Aristolochic acid nephropathy: A worldwide problem. Kidney Int 2008; 74: 158-169.
7. Laing C, Hamour S, Sheaff M, Miller R, Woolfson R. Chinese herbal uropathy and nephropathy. Lancet 2006; 368: 338.
8. Stewart JH, Hobbs JB, McCredie MR. Morphologic evidence that analgesic-induced kidney pathology contributes to the progression of tumors of the renal pelvis. Cancer 1999; 86: 1576-1582.
9. Catto JW, Azzouzi AR, Rehman I, Feeley KM, Cross SS, Amira N, Fromont G, Sibony M, Cussenot O, Meuth M, Hamdy FC. Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma. J Clin Oncol 2005; 23: 2903-2910.
10. Zhang Z, Furge KA, Yang XJ, Teh BT, Hansel DE. Comparative gene expression profiling analysis of urothelial carcinoma of the renal pelvis and bladder. BMC Med Genomics 2010; 3: 58.
11. Catto JW, Yates DR, Rehman I, Azzouzi AR, Patterson J, Sibony M, Cussenot O, Hamdy FC. Behavior of urothelial carcinoma with respect to anatomical location. J Urol 2007; 177: 1715-1720.
12. Hartwell LH, Kastan MB. Cell cycle control and cancer. Science 1994; 266: 1821-1828.
13. Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004; 432: 316-323.
14. Zetterberg A, Larsson O, Wiman KG. What is the restriction point? Curr Opin Cell Biol 1995; 7: 835-842.
15. Zhang N, Pati D. Sororin is a master regulator of sister chromatid cohesion and separation. Cell cycle 2012; 11: 2073-2083.
16. Zhang N, Pati D. Handcuff for sisters: A new model for sister chromatid cohesion. Cell cycle 2009; 8: 399-402.
17. Nguyen MH, Koinuma J, Ueda K, Ito T, Tsuchiya E, Nakamura Y, Daigo Y. Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis. Cancer Res 2010; 70: 5337-5347.
18. Huang WW, Huang HY, Liao AC, Shiue YL, Tai HL, Lin CM, Wang YH, Lin CN, Shen KH, Li CF. Primary urothelial carcinoma of the upper tract: Important clinicopathological factors predicting bladder recurrence after surgical resection. Pathol Int 2009; 59: 642-649.
19. Wu LC, Chen LT, Tsai YJ, Lin CM, Lin CY, Tian YF, Sheu MJ, Uen YH, Shiue YL, Wang YH, Yang SJ, Wu WR, Li SH, Iwamuro M, Kobayasshi N, Huang HY, Li CF. Alpha-methylacyl coenzyme a racemase overexpression in gallbladder carcinoma confers an independent prognostic indicator. J Clin Pathol 2012; 65: 309-314.
20. Budwit-Novotny DA, McCarty KS, Cox EB, Soper JT, Mutch DG, Creasman WT, Flowers JL, McCarty KS Jr. Immunohistochemical analyses of estrogen receptor in endometrial adenocarcinoma using a monoclonal antibody. Cancer Res 1986; 46: 5419-5425.
21. McClelland RA, Finlay P, Walker KJ, Nicholson D, Robertson JF, Blamey RW, Nicholson RI. Automated quantitation of immunocytochemically localized estrogen receptors in human breast cancer. Cancer Res 1990; 50: 3545-3550.
22. Bartek J, Lukas J. Mammalian G1- and Sphase checkpoints in response to DNA damage. Curr Opin Cell Biol 2001; 13: 738-747.
23. Xu B, Kim ST, Lim DS, Kastan MB. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol Cell Biol 2002; 22: 1049-1059.
24. Nyberg KA, Michelson RJ, Putnam CW, Weinert TA. Toward maintaining the genome: DNA damage and replication checkpoints. Annu Rev Genet 2002; 36: 617-656.
25. Massague J. G1 cell-cycle control and cancer. Nature 2004; 432: 298-306.
26. Rankin S, Ayad NG, Kirschner MW. Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates. Mol Cell 2005; 18: 185-200.
27. Schmitz J, Watrin E, Lenart P, Mechtler K, Peters JM. Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. Curr Biol 2007; 17: 630-636.