-
1
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science. 2009;326(5950): 285-289.
-
(2009)
Science
, vol.326
, Issue.5950
, pp. 285-289
-
-
Walker, L.M.1
-
2
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: Individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
Simek MD, et al. Human immunodeficiency virus type 1 elite neutralizers: Individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J Virol. 2009;83(14): 7337-7348.
-
(2009)
J Virol
, vol.83
, Issue.14
, pp. 7337-7348
-
-
Simek, M.D.1
-
3
-
-
84863774072
-
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
-
Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science. 2012;337(6091): 183-186.
-
(2012)
Science
, vol.337
, Issue.6091
, pp. 183-186
-
-
Burton, D.R.1
Poignard, P.2
Stanfield, R.L.3
Wilson, I.A.4
-
4
-
-
84866495323
-
Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies
-
Kwong PD, Mascola JR. Human antibodies that neutralize HIV-1: Identification, structures, and B cell ontogenies. Immunity. 2012;37(3): 412-425.
-
(2012)
Immunity
, vol.37
, Issue.3
, pp. 412-425
-
-
Kwong, P.D.1
Mascola, J.R.2
-
5
-
-
84926453015
-
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer
-
Derking R, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. PLoS Pathog. 2015;11(3): E1004767.
-
(2015)
PLoS Pathog
, vol.11
, Issue.3
, pp. e1004767
-
-
Derking, R.1
-
6
-
-
84879302728
-
HIV-1 neutralizing antibodies: Understanding nature's pathways
-
Mascola JR, Haynes BF. HIV-1 neutralizing antibodies: Understanding nature's pathways. Immunol Rev. 2013;254(1): 225-244.
-
(2013)
Immunol Rev
, vol.254
, Issue.1
, pp. 225-244
-
-
Mascola, J.R.1
Haynes, B.F.2
-
7
-
-
84898538468
-
Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection
-
Derdeyn CA, Moore PL, Morris L. Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection. Curr Opin HIV AIDS. 2014;9(3): 210-216.
-
(2014)
Curr Opin HIV AIDS
, vol.9
, Issue.3
, pp. 210-216
-
-
Derdeyn, C.A.1
Moore, P.L.2
Morris, L.3
-
8
-
-
84930389498
-
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth
-
Willis JR, et al. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. J Clin Invest. 2015;125(6): 2523-2531.
-
(2015)
J Clin Invest
, vol.125
, Issue.6
, pp. 2523-2531
-
-
Willis, J.R.1
-
9
-
-
84922982202
-
Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes
-
Kong R, et al. Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes. J Virol. 2015;89(5): 2659-2671.
-
(2015)
J Virol
, vol.89
, Issue.5
, pp. 2659-2671
-
-
Kong, R.1
-
10
-
-
84890858459
-
Crystal structure of a soluble cleaved HIV-1 envelope trimer
-
Julien JP, et al. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science. 2013;342(6165): 1477-1483.
-
(2013)
Science
, vol.342
, Issue.6165
, pp. 1477-1483
-
-
Julien, J.P.1
-
11
-
-
84909640954
-
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
-
Pancera M, et al. Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature. 2014;514(7523): 455-461.
-
(2014)
Nature
, vol.514
, Issue.7523
, pp. 455-461
-
-
Pancera, M.1
-
12
-
-
84890859441
-
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer
-
Lyumkis D, et al. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science. 2013;342(6165): 1484-1490.
-
(2013)
Science
, vol.342
, Issue.6165
, pp. 1484-1490
-
-
Lyumkis, D.1
-
13
-
-
84878618663
-
HIV-1 envelope glycoprotein structure
-
Merk A, Subramaniam S. HIV-1 envelope glycoprotein structure. Curr Opin Struct Biol. 2013;23(2): 268-276.
-
(2013)
Curr Opin Struct Biol
, vol.23
, Issue.2
, pp. 268-276
-
-
Merk, A.1
Subramaniam, S.2
-
14
-
-
83455254775
-
Structure of HIV-1 gp120 V1/ V2 domain with broadly neutralizing antibody PG9
-
McLellan JS, et al. Structure of HIV-1 gp120 V1/ V2 domain with broadly neutralizing antibody PG9. Nature. 2011;480(7377): 336-343.
-
(2011)
Nature
, vol.480
, Issue.7377
, pp. 336-343
-
-
McLellan, J.S.1
-
15
-
-
77954982131
-
Crystal structure of PG16 and chimeric dissection with somatically related PG9: Structure-function analysis of two quaternary- specific antibodies that effectively neutralize HIV-1
-
Pancera M, et al. Crystal structure of PG16 and chimeric dissection with somatically related PG9: Structure-function analysis of two quaternary- specific antibodies that effectively neutralize HIV-1. J Virol. 2010;84(16): 8098-8110.
-
(2010)
J Virol
, vol.84
, Issue.16
, pp. 8098-8110
-
-
Pancera, M.1
-
16
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature. 2011;477(7365): 466-470.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 466-470
-
-
Walker, L.M.1
-
17
-
-
0028865465
-
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG
-
Trkola A, et al. Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG. J Virol. 1995;69(11): 6609-6617.
-
(1995)
J Virol
, vol.69
, Issue.11
, pp. 6609-6617
-
-
Trkola, A.1
-
18
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science. 2010;329(5993): 856-861.
-
(2010)
Science
, vol.329
, Issue.5993
, pp. 856-861
-
-
Wu, X.1
-
19
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
Huang J, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 2012;491(7424): 406-412.
-
(2012)
Nature
, vol.491
, Issue.7424
, pp. 406-412
-
-
Huang, J.1
-
20
-
-
84900467984
-
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers
-
Blattner C, et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity. 2014;40(5): 669-680.
-
(2014)
Immunity
, vol.40
, Issue.5
, pp. 669-680
-
-
Blattner, C.1
-
21
-
-
84899909771
-
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike
-
Scharf L, et al. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Rep. 2014;7(3): 785-795.
-
(2014)
Cell Rep
, vol.7
, Issue.3
, pp. 785-795
-
-
Scharf, L.1
-
22
-
-
84921607768
-
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41- gp120 interface
-
Huang J, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41- gp120 interface. Nature. 2014;515(7525): 138-142.
-
(2014)
Nature
, vol.515
, Issue.7525
, pp. 138-142
-
-
Huang, J.1
-
23
-
-
84055181327
-
Rapid development of glycanspecific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
-
Walker LM, et al. Rapid development of glycanspecific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque. Proc Natl Acad Sci U S A. 2011;108(50): 20125-20129.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.50
, pp. 20125-20129
-
-
Walker, L.M.1
-
24
-
-
79551518897
-
Characteristics of the earliest cross-neutralizing antibody response to HIV-1
-
Mikell I, Sather DN, Kalams SA, Altfeld M, Alter G, Stamatatos L. Characteristics of the earliest cross-neutralizing antibody response to HIV-1. PLoS Pathog. 2011 7(1): E1001251.
-
(2011)
PLoS Pathog
, vol.7
, Issue.1
, pp. e1001251
-
-
Mikell, I.1
Sather, D.N.2
Kalams, S.A.3
Altfeld, M.4
Alter, G.5
Stamatatos, L.6
-
25
-
-
84875759341
-
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
-
Klein F, et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell. 2013;153(1): 126-138.
-
(2013)
Cell
, vol.153
, Issue.1
, pp. 126-138
-
-
Klein, F.1
-
26
-
-
77954912140
-
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
-
Pejchal R, et al. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proc Natl Acad Sci U S A. 2010;107(25): 11483-11488.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.25
, pp. 11483-11488
-
-
Pejchal, R.1
-
27
-
-
84860706280
-
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes
-
Briney BS, Willis JR, Crowe JE Jr. Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes. PLoS One. 2012;7(5): E36750.
-
(2012)
PLoS One
, vol.7
, Issue.5
, pp. e36750
-
-
Briney, B.S.1
Willis, J.R.2
Crowe, J.E.3
-
28
-
-
84875034460
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
-
Julien JP, et al. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc Natl Acad Sci U S A. 2013;110(11): 4351-4356.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.11
, pp. 4351-4356
-
-
Julien, J.P.1
-
29
-
-
84878519611
-
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
-
Julien JP, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog. 2013;9(5): E1003342.
-
(2013)
PLoS Pathog
, vol.9
, Issue.5
, pp. e1003342
-
-
Julien, J.P.1
-
30
-
-
50649095790
-
Macromolecular modeling with rosetta
-
Das R, Baker D. Macromolecular modeling with rosetta. Annu Rev Biochem. 2008;77: 363-382.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 363-382
-
-
Das, R.1
Baker, D.2
-
31
-
-
84899991983
-
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
-
Doria-Rose NA, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 2014;509(7498): 55-62.
-
(2014)
Nature
, vol.509
, Issue.7498
, pp. 55-62
-
-
Doria-Rose, N.A.1
-
32
-
-
84929247213
-
Immune system regulation in the induction of broadly neutralizing HIV-1 antibodies
-
Kelsoe G, Verkoczy L, Haynes BF. Immune system regulation in the induction of broadly neutralizing HIV-1 antibodies. Vaccines (Basel). 2014;2(1): 1-14.
-
(2014)
Vaccines (Basel
, vol.2
, Issue.1
, pp. 1-14
-
-
Kelsoe, G.1
Verkoczy, L.2
Haynes, B.F.3
-
33
-
-
84919430580
-
Polyreactivity and autoreactivity among HIV-1 antibodies
-
Liu M, et al. Polyreactivity and autoreactivity among HIV-1 antibodies. J Virol. 2015;89(1): 784-798.
-
(2015)
J Virol
, vol.89
, Issue.1
, pp. 784-798
-
-
Liu, M.1
|