Anti-dsDNA antibody induces soluble fibronectin secretion by proximal renal tubular epithelial cells and downstream increase of TGF-β1 and collagen synthesis

Journal of Autoimmunity

Volumn 58, Issue , 2015, Pages 111-122

  Yung, Susan ^a   Ng, Claudia Y C ^a   Ho, Sau Kwan ^a   Cheung, Kwok Fan ^a   Chan, Kwok Wah ^a   Zhang, Qing ^a   Chau, Mel K M ^a   Chan, Tak Mao ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anti dsDNA antibodies; Fibronectin; Lupus nephritis; Mycophenolic acid; Proximal renal tubular epithelial cells

Indexed keywords

COLLAGEN TYPE 1; DOUBLE STRANDED DNA ANTIBODY; FIBRONECTIN; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MYCOPHENOLIC ACID; NEUTRALIZING ANTIBODY; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; ANTINUCLEAR ANTIBODY; BLOCKING ANTIBODY; COLLAGEN; DNA;

ARTICLE; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY BIOPSY; KIDNEY TUBULE CELL; LUPUS ERYTHEMATOSUS NEPHRITIS; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; EPITHELIUM CELL; FIBROSIS; GENETICS; IMMUNOLOGY; KIDNEY PROXIMAL TUBULE; LUPUS NEPHRITIS; METABOLISM; PATHOLOGY; UPREGULATION;

ANTIBODIES, ANTINUCLEAR; ANTIBODIES, BLOCKING; CELLS, CULTURED; COLLAGEN; DNA; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBRONECTINS; FIBROSIS; HUMANS; KIDNEY TUBULES, PROXIMAL; LUPUS NEPHRITIS; MYCOPHENOLIC ACID; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84930376257     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.01.008     Document Type: Article

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