Development and bioevaluation of nanofibers with blood-derived growth factors for dermal wound healing

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 1, 2014, Pages 64-74

  Bertoncelj, Valentina ^a   Pelipenko, Jan ^a   Kristl, Julijana ^a   Jeras, Matjaž ^a,b,c   Cukjati, Marko ^b   Kocbek, Petra ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b BLOOD TRANSFUSION CENTRE OF SLOVENIA   (Slovenia)

^c Celica Biomedical Sciences Center   (Slovenia)

Author keywords

Electrospinning; Fibroblasts; Keratinocytes; Nanotechnology; Platelet rich plasma; Polymer nanofibers; Wound healing

Indexed keywords

CHITOSAN; MACROGOL DERIVATIVE; NANOFIBER; POLYMER; SIGNAL PEPTIDE;

CELL MOTION; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; FIBROBLAST; HUMAN; INTRADERMAL DRUG ADMINISTRATION; KERATINOCYTE; METABOLISM; NANOTECHNOLOGY; SCANNING ELECTRON MICROSCOPY; SKIN; THROMBOCYTE RICH PLASMA; WOUND HEALING;

ADMINISTRATION, CUTANEOUS; CELL MOVEMENT; CELL PROLIFERATION; CHITOSAN; FIBROBLASTS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; MICROSCOPY, ELECTRON, SCANNING; NANOFIBERS; NANOTECHNOLOGY; PLATELET-RICH PLASMA; POLYETHYLENE GLYCOLS; POLYMERS; SKIN; WOUND HEALING;

EID: 84930373818     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.06.001     Document Type: Article

References (38)

1. M. Caceres, R. Hidalgo, A. Sanz, J. Martinez, P. Riera, and P.C. Smith Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts J. Periodontol. 79 2008 714 720
2. P. Martin Wound healing-aiming for perfect skin regeneration Science 276 1997 75 81
3. S. Werner, and R. Grose Regulation of wound healing by growth factors and cytokines Physiol. Rev. 83 2003 835 870
4. S. Mehta, and J.T. Watson Platelet rich concentrate: basic science and current clinical applications J. Orthop. Trauma 22 2008 432 438
5. E. Anitua, M.H. Alkhraisat, and G. Orive Perspectives and challenges in regenerative medicine using plasma rich in growth factors J. Control. Release 157 2012 29 38
6. T.E. Foster, B.L. Puskas, B.R. Mandelbaum, M.B. Gerhardt, and S.A. Rodeo Platelet-rich plasma: from basic science to clinical applications Am. J. Sports Med. 37 2009 2259 2272
7. S.G. Boswell, B.J. Cole, E.A. Sundman, V. Karas, and L.A. Fortier Platelet-rich plasma: a milieu of bioactive factors Arthroscopy 28 2012 429 439
8. S.E. Lynch, R.B. Colvin, and H.N. Antoniades Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds J.Clin. Invest. 84 1989 640 646
9. E. Anitua, M. Sanchez, G. Orive, and I. Andia Delivering growth factors for therapeutics Trends Pharmacol. Sci. 29 2008 37 41
10. N. Bhardwaj, and S.C. Kundu Electrospinning: a fascinating fiber fabrication technique Biotechnol. Adv. 28 2010 325 347
11. E. Anitua, J.J. Aguirre, J. Algorta, E. Ayerdi, A.I. Cabezas, G. Orive, and I. Andia Effectiveness of autologous preparation rich in growth factors for the treatment of chronic cutaneous ulcers J. Biomed. Mater. Res. B Appl. Biomater. 84 2008 415 421
12. L. Creaney, and B. Hamilton Growth factor delivery methods in the management of sports injuries: the state of play Br. J. Sports Med. 42 2008 314 320
13. A. Mishra, and T. Pavelko Treatment of chronic elbow tendinosis with buffered platelet-rich plasma Am. J. Sports Med. 34 2006 1774 1778
14. P. Koria Delivery of growth factors for tissue regeneration and wound healing BioDrugs 26 2012 163 175
15. S. Sahoo, L.T. Ang, J.C. Goh, and S.L. Toh Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications J. Biomed. Mater. Res. A 93 2010 1539 1550
16. V. Beachley, and X. Wen Polymer nanofibrous structures: fabrication, biofunctionalization, and cell interactions Prog. Polym. Sci. 35 2010 868 892
17. N.M. Alves, I. Pashkuleva, R.L. Reis, and J.F. Mano Controlling cell behavior through the design of polymer surfaces Small 6 2010 2208 2220
18. S.S. Said, A.K. Aloufy, O.M. El-Halfawy, N.A. Boraei, and L.K. El-Khordagui Antimicrobial PLGA ultrafine fibers: interaction with wound bacteria Eur. J. Pharm. Biopharm. 79 2011 108 118
19. X. Fu, M. Xu, J. Liu, Y. Qi, S. Li, and H. Wang Regulation of migratory activity of human keratinocytes by topography of multiscale collagen-containing nanofibrous matrices Biomaterials 35 2014 1496 1506
20. C.J. Powers, S.W. McLeskey, and A. Wellstein Fibroblast growth factors, their receptors and signaling Endocr. Relat. Cancer 7 2000 165 197
21. J. van den Dolder, R. Mooren, A.P. Vloon, P.J. Stoelinga, and J.A. Jansen Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells Tissue Eng. 12 2006 3067 3073
22. F. Creeper, and S. Ivanovski Effect of autologous and allogenic platelet-rich plasma on human gingival fibroblast function Oral Dis. 18 2012 494 500
23. D.M. Dohan Ehrenfest, L. Rasmusson, and T. Albrektsson Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF) Trends Biotechnol. 27 2009 158 167
24. N.V. Kalmykova, E.V. Skorobogataya, M.A. Berestovoy, P.V. Kruglyakov, M.A. Estrina, B.V. Afanasiev, and D.G. Polintsev Comparative characteristics of platelet lysates from different donors Bull. Exp. Biol. Med. 151 2011 547 549
25. S.A. Garside, C.R. Harlow, S.G. Hillier, H.M. Fraser, and F.H. Thomas Thrombospondin-1 inhibits angiogenesis and promotes follicular atresia in a novel in vitro angiogenesis assay Endocrinology 151 2010 1280 1289
26. Y. Mirochnik, A. Kwiatek, and O.V. Volpert Thrombospondin and apoptosis: molecular mechanisms and use for design of complementation treatments Curr. Drug Targets 9 2008 851 862
27. P. Sangsanoh, O. Suwantong, A. Neamnark, P. Cheepsunthorn, P. Pavasant, and P. Supaphol In vitro biocompatibility of electrospun and solvent-cast chitosan substrata towards Schwann, osteoblast, keratinocyte and fibroblast cells Eur. Polym. J. 46 2010 428 440
28. K. Okuda, T. Kawase, M. Momose, M. Murata, Y. Saito, H. Suzuki, L.F. Wolff, and H. Yoshie Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-β and modulates the proliferation of periodontally related cells in vitro J. Periodontol. 74 2003 849 857
29. C.W. Hsu, K. Yuan, and C.C. Tseng The negative effect of plattelet-rich plasma on the growth of human cells is associated with secreted thrombospondin-1 Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 107 2009 185 192
30. D.H. Kim, Y.J. Je, C.D. Kim, Y.H. Lee, Y.J. Seo, J.H. Lee, and Y.J. Seo Can platelet-rich plasma be used for skin rejuvenation? Evaluation of effects on platelet-rich plasma on human dermal fibroblast Ann. Dermatol. 23 2011 424 431
31. E. Anitua, M. Sanchez, J. Merayo-Lloves, M. De la Fuente, F. Muruzabal, and G. Orive Plasma rich in growth factors (PRGF-Endoret) stimulates proliferation and migration of primary keratocytes and conjunctival fibroblasts and inhibits and reverts TGF-beta1-Induced myodifferentiation Invest. Ophthalmol. Vis. Sci. 52 2011 6066 6073
32. S.A. Sell, P.S. Wolfe, J.J. Ericksen, D.G. Simpson, and G.L. Bowlin Incorporating platelet-rich plasma into electrospun scaffolds for tissue engineering applications Tissue Eng. Part A 17 2011 2723 2737
33. R. Rosic, P. Kocbek, J. Pelipenko, J. Kristl, and S. Baumgartner Nanofibers and their biomedical use Acta Pharm. 63 2013 295 304
34. J. Pelipenko, P. Kocbek, B. Govedarica, R. Rošic, S. Baumgartner, and J. Kristl The topography of electrospun nanofibers and its impact on the growth and mobility of keratinocytes Eur. J. Pharm. Biopharm. 84 2013 401 411
35. A. Vasconcelos, and A. Cavaco-Paulo Wound dressings for a proteolytic-rich environment Appl. Microbiol. Biotechnol. 90 90 2011 445 460
36. P.S. Wolfe, S.A. Sell, J.J. Ericksen, D.G. Simpson, and G.L. Bowlin The creation of electrospun nanofibers from pletelet rich plasma J. Tissue Sci. Eng. 2 2011 2
37. Z. Xie, C.B. Paras, H. Weng, P. Punnakitikashem, L.C. Su, K. Vu, L. Tang, J. Yang, and K.T. Nguyen Dual growth factor releasing multi-functional nanofibers for wound healing Acta Biomater. 9 2013 9351 9359
38. B. Jankovic, J. Pelipenko, M. Skarabot, I. Musevic, and J. Kristl The design trend in tissue-engineering scaffolds based on nanomechanical properties of individual electrospun nanofibers Int. J. Pharm. 455 2013 338 347