Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Bergeron, Éric ^a   Zivcec, Marko ^a   Chakrabarti, Ayan K ^a   Nichol, Stuart T ^a   Albariño, César G ^a   Spiropoulou, Christina F ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; FURIN; GLYCOPROTEIN; GP38; PROPROTEIN CONVERTASE 1; RNA POLYMERASE; UNCLASSIFIED DRUG; FURIN PROTEIN, HUMAN; MEMBRANE-BOUND TRANSCRIPTION FACTOR PEPTIDASE, SITE 1; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN; RNA; RNA, RECOMBINANT; SERINE PROTEINASE; VIRAL PROTEIN;

ARTICLE; CRIMEAN CONGO HEMORRHAGIC FEVER VIRUS; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; NONHUMAN; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CLEAVAGE; PROTEIN METABOLISM; REVERSE GENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRION; WESTERN BLOTTING; AMINO ACID SUBSTITUTION; ANIMAL; CELL CLONE; CELL LINE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COMPARATIVE STUDY; CRICETULUS; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HUMAN; LIVER CELL; MESOCRICETUS; METABOLISM; MUTATION; NAIROVIRUS; PROTEIN DEGRADATION; PROTEIN MOTIF; VIROLOGY;

BUNYAVIRIDAE; CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS; NAIROVIRUS; RNA VIRUSES;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; CLONE CELLS; CRICETULUS; FURIN; GLYCOPROTEINS; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HEPATOCYTES; HUMANS; MESOCRICETUS; MUTATION; PEPTIDE FRAGMENTS; PROPROTEIN CONVERTASES; PROTEOLYSIS; RECOMBINANT PROTEINS; RNA; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84930342797     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004879     Document Type: Article

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