Crimean-Congo hemorrhagic fever virus glycoprotein proteolytic processing by subtilase SKI-1

Journal of Virology

Volumn 77, Issue 16, 2003, Pages 8640-8649

  Vincent, Martin J ^a   Sanchez, Angela J ^a   Erickson, Bobbie R ^a   Basak, Ajoy ^b   Chretien, Michel ^b   Seidah, Nabil G ^c   Nichol, Stuart T ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLARGINYLLEUCYLLEUCINE; ARGINYLLYSYLPROLYLLEUCINE; GC GLYCOPROTEIN; GN GLYCOPROTEIN; PROTEINASE; SKI 1 PROTEASE; TETRAPEPTIDE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

AMINO TERMINAL SEQUENCE; ARENAVIRUS; ARTICLE; BINDING SITE; BUNYAVIRUS; CHO CELL; DNA FLANKING REGION; ENDOPLASMIC RETICULUM; LASSA VIRUS; NAIRO VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL COMPARTMENTATION; CELL LINE; DNA PRIMERS; ENDOPLASMIC RETICULUM; GLYCOPROTEINS; GOLGI APPARATUS; HEMORRHAGIC FEVER VIRUS, CRIMEAN-CONGO; HUMANS; HYDROLYSIS; PROPROTEIN CONVERTASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

EID: 0042709472     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.16.8640-8649.2003     Document Type: Article

References (26)

1. Basak, A., M. Zhong, J. S. Munzer, M. Chrétien, and N. G. Seidah. 2001. Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses - a comparative analysis using fluorogenic peptides. Biochem. J. 353:537-545.
2. Basak, A., M. Chrétien, and N. G. Seidah. 2002. A rapid fluorometric assay for the proteloytic activity of SKI-1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus. FEBS Lett. 514:333-339.
3. Brandt, W. E., E. L. Buescher, and F. M. Hetrick. 1967. Production and characterization of arbovirus antibody in mouse ascitic fluid. Am. J. Trop. Med. Hyg. 16:339-347.
4. Burns, J. W., and M. J. Buchmeier. 1993. Glycoproteins of the arenaviruses, p. 17-35. In M. S. Salvato (ed.), The Arenaviridae. Plenum Press, New York, N.Y.
5. Decroly, E., M. Vandenbranden, J. M. Ruysschaert, J. Cogniaux, G. S. Jacob, S. C. Howard, G. Marshall, A. Kompelli, A. Basak, F. Jean, C. Lazure, S. Benjannet, M. Chrétien, R. Day, and N. G. Seidah. 1994. The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-I SU) and gp41 (HIV-I TM). J. Biol. Chem. 269:12240-12247.
6. Decroly, E., S. Wouters, C. Di Bello, C. Lazure, J. M Ruysschaert, and N. G. Seidah. 1996. Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines. J. Biol. Chem. 271:30442-30450.
7. Elagoz, A., S. Benjannet, A. Mammarbassi, L. Wickham, and N. G. Seidah. 2002. Biosynthesis and cellular trafficking of the convertase SKI-1/SIP. Ectodomain shedding requires SKI-1 activity. J. Biol. Chem. 277:11265-11275.
8. Fuerst, T. R., P. L. Earl, and B. Moss. 1987. Use of a hybrid virus-T7 RNA polymerase system for expression of target genes. Mol. Cell. Biol. 7:2538-2544.
9. Hallenberger, S., M. Moulard, M. Sordel, H.-D. Klenk, and W. Garten. 1997. The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells. J. Virol. 71:1036-1045.
10. Hallenberger, S., V. Bosch, H. Angliker, E. Shaw, H.-D. Klenk, and W. Garten. 1992. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature 360:358-361.
11. Klenk, H.-D., and W. Garten. 1994. Host cell proteases controlling virus pathogenicity. Trends Microbiol. 2:39-43.
12. Lenz, O., J. ter Meulen, H.-D. Klenk, N. G. Seidah, and W. Garten. 2001. The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P. Proc. Natl. Acad. Sci. USA 98:12701-12705.
13. Lenz, O., J. ter Meulen, H. Feldmann, H.-D. Klenk, and W. Garten. 2000. Identification of a novel consensus sequence at the cleavage site of the Lassa virus glycoprotein. J. Virol. 74:11418-11421.
14. Nichol, S. T. 2001. Bunyaviruses, p. 1603-1633. In D. M. Knipe and P. M. Howley (ed.), Fields virology, vol. 2. Lippincott Williams and Wilkins, Philadelphia, Pa.
15. Rawson, R. B., D. Cheng, M. S. Brown, and J. L. Goldstein. 1998. Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1. J. Biol. Chem. 273:28261-28269.
16. Sanchez, A. J., M. J. Vincent, and S. T. Nichol. 2002. Characterization of the glycoproteins of Crimean-Congo hemorrhagic fever virus. J. Virol. 14:7263-7275.
17. Schmaljohn, C. S., and J. W. Hooper. 2001. Bunyaviridae: the viruses and their replication, p. 1581-1602. In D. M. Knipe and P. M. Howley (ed.), Fields virology, vol. 2. Lippincott Williams and Wilkins, Philadelphia, Pa.
18. Seidah, N. G., S. J. Mowla, J. Hamelin, A. M. Mamarbachi, S. Benjannet, B. B. Touré, A. Basak, J. S. Munzer, J. Marcinkiewicz, M. Zhong, J. C. Barale, C. Lazure, R. A. Murphy, M. Chretien, and M. Marcinkiewicz. 1999. Mammalian subtilase/kexin isozyme SKI-1: a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Proc. Natl. Acad. Sci. USA 96:1321-1326.
19. Spiropoulou, C. F., S. Kunz, P. E. Rollin, K. P. Campbell, and M. B. A. Oldstone. 2002. New World arenavirus clade C, but not clade A and B viruses, utilize alpha-dystroglycan as their major receptor. J. Virol. 76:5140-5146.
20. Stieneke-Grober, A., M. Vey, H. Angliker, H., E. Shaw, G. Thomas, C. Roberts, H.-D. Klenk, and W. Garten. 1992. Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO. J. 11:2407-2414.
21. Touré, B. B., J. S. Munzer, A. Basak, S. Benjannet, J. Rochemont, C. Lazure, M. Chrétien, and N. G. Seidah. 2000. Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment. J. Biol. Chem. 275:2349-2358.
22. Vincent, M. J., N. U. Raja, and M. A. Jabbar. 1993. Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum. J. Virol. 67:5538-5549.
23. Volchkov, V. E., H. Feldmann, V. A. Volchkova, and H.-D. Klenk. 1998. Processing of the Ebola virus glycoprotein by the proprotein convertase furin. Proc. Natl. Acad. Sci. USA 95:5762-5767.
24. Volchkov, V. E., V. A. Volchkova, U. Stroher, S. Becker, O. Dolnik, M. Cieplik, W. Garten, H.-D. Klenk, and H. Feldman. 2000. Proteolytic processing of Marburg virus glycoprotein. Virology 268:1-6.
25. Walker, J. A., S. S. Molloy, G. Thomas, T. Sakaguchi, T. Yoshida, T. M. Chamber, and Y. Kawaoka. 1994. Sequence specificity of furin, a proprotein-processing endoprotease, for the hemagglutinin of a virulent avian influenza virus. J. Virol. 68:1213-1218.
26. Watanabe, M., A. Hirano, S. Stenglein, J. Nelson, G. Thomas, and T. C. Wong. 1995. Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus. J. Virol. 69:3206-3210.