Reverse genetics recovery of lujo virus and role of virus RNA secondary structures in efficient virus growth

Journal of Virology

Volumn 86, Issue 19, 2012, Pages 10759-10765

  Bergeron, Éric ^a   Chakrabarti, Ayan K ^a   Bird, Brian H ^a   Dodd, Kim A ^a   McMullan, Laura K ^a   Spiropoulou, Christina F ^a   Nichol, Stuart T ^a   Albariño, César G ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; LUCIFERASE; NUCLEOTIDE; SPACER DNA; VIRUS DNA; VIRUS RNA;

ARENAVIRUS; ARTICLE; DNA STRUCTURE; ENERGY METABOLISM; GENE EXPRESSION; GENE SEQUENCE; GENE STRUCTURE; LUJO VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPLICON; REPORTER GENE; REVERSE GENETICS; TRANSCRIPTION TERMINATION; VIROGENESIS; VIRUS ATTENUATION; VIRUS GENOME; VIRUS ISOLATION;

3' UNTRANSLATED REGIONS; ANIMALS; ARENAVIRUS; BASE SEQUENCE; CRICETINAE; DNA, COMPLEMENTARY; GENES, REPORTER; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; NUCLEOTIDES; PLASMIDS; RNA VIRUSES; RNA, VIRAL; SOUTH AFRICA; TIME FACTORS; VIRULENCE; ZAMBIA;

ARENAVIRUS; RODENTIA;

EID: 84869005767     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01144-12     Document Type: Article

References (38)

1. Albariño CG, et al. 2009. Efficient reverse genetics generation of infectious Junin viruses differing in glycoprotein processing. J. Virol. 83:5606-5614.
2. Albariño CG, et al. 2011. Efficient rescue of recombinant Lassa virus reveals the influence of S segment noncoding regions on virus replication and virulence. J. Virol. 85:4020-4024.
3. Albariño CG, et al. 2011. The major determinant of attenuation in mice of the Candid1 vaccine for Argentine hemorrhagic fever is located in the G2 glycoprotein transmembrane domain. J. Virol. 85:10404-10408.
4. Auperin DD, Compans RW, Bishop DH. 1982. Nucleotide sequence conservation at the 3= termini of the virionRNAspecies of New World and Old World arenaviruses. Virology 121:200-203.
5. Auperin D, et al. 1982. Analyses of the genomes of prototype pichinde arenavirus and a virulent derivative of Pichinde Munchique: evidence for sequence conservation at the 3= termini of their viral RNA species. Virology 116:363-367.
6. Barr JN, Elliott RM, Dunn EF, Wertz GW. 2003. Segment-specific terminal sequences of Bunyamwera bunyavirus regulate genome replication. Virology 311:326-338.
7. Bergeron É, Albariño CG, Khristova ML, Nichol ST. 2010. Crimean- Congo hemorrhagic fever virus-encoded ovarian tumor protease activity is dispensable for virus RNA polymerase function. J. Virol. 84:216-226.
8. Briese T, et al. 2009. Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa. PLoS Pathog. 5:e1000455. doi:10.1371/journal.ppat.1000455.
9. Buchholz UJ, Finke S, Conzelmann KK. 1999. Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter. J. Virol. 73:251-259.
10. Charrel RN, de Lamballerie X. 2010. Zoonotic aspects of arenavirus infections. Vet. Microbiol. 140:213-220.
11. Clerx-van Haaster CM, Akashi H, Auperin DD, Bishop DH. 1982. Nucleotide sequence analyses and predicted coding of bunyavirus genome RNA species. J. Virol. 41:119-128.
12. Cornu TI, de La Torre JC. 2002. Characterization of the arenavirus RING finger Z protein regions required for Z-mediated inhibition of viral RNA synthesis. J. Virol. 76:6678-6688.
13. Emonet SE, Urata S, de La Torre JC. 2011. Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies. Virology 411:416-425.
14. Flatz L, Bergthaler A, de La Torre JC, Pinschewer DD. 2006. Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc. Natl. Acad. Sci. U. S. A. 103:4663-4668.
15. Flick R, Neumann G, Hoffmann E, Neumeier E, Hobom G. 1996. Promoter elements in the influenza vRNA terminal structure. RNA 2:1046-1057.
16. Garcin D, Kolakofsky D. 1990. A novel mechanism for the initiation of Tacaribe arenavirus genome replication. J. Virol. 64:6196-6203.
17. Hass M, et al. 2006. Mutational analysis of the Lassa virus promoter. J. Virol. 80:12414-12419.
18. Iapalucci S, López N, Franze-Fernández MT. 1991. The 3= end termini of the Tacaribe arenavirus subgenomic RNAs. Virology 182:269-278.
19. Kranzusch PJ, et al. 2010. Assembly of a functional Machupo virus polymerase complex. Proc. Natl. Acad. Sci. U. S. A. 107:20069-20074.
20. Lee KJ, Novella IS, Teng MN, Oldstone MB, de La Torre JC. 2000. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J. Virol. 74:3470-3477.
21. Le May N, et al. 2004. TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus. Cell 116:541-550.
22. López N, Franze-Fernandez MT. 2007. A single stem-loop structure in Tacaribe arenavirus intergenic region is essential for transcription termination but is not required for a correct initiation of transcription and replication. Virus Res. 124:237-244.
23. López N, Jácamo R, Franze-Fernández MT. 2001. Transcription and RNAreplication of tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes. J. Virol.75:12241-12251.
24. Marq J-B, Hausmann S, Veillard N, Kolakofsky D, Garcin D. 2011. Short double-stranded RNAs with an overhanging 5= ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys. J. Biol. Chem. 286:6108-6116.
25. Marq J-B, Kolakofsky D, Garcin D. 2010. Unpaired 5= ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I. J. Biol. Chem. 285:18208-18216.
26. Morin B, et al. 2010. The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription. PLoS Pathog. 6:e1001038. doi:10.1371/journal.ppat.1001038.
27. Müller S, Günther S. 2007. Broad-spectrum antiviral activity of small interfering RNA targeting the conserved RNA termini of Lassa virus. Antimicrob. Agents Chemother. 51:2215-2218.
28. Palmer EL, Obijeski JF, Webb PA, Johnson KM. 1977. The circular, segmented nucleocapsid of an arenavirus-Tacaribe virus. J. Gen. Virol. 36:541-545.
29. Paweska JT, et al. 2009. Nosocomial outbreak of novel arenavirus infection, southern Africa. Emerg. Infect. Dis. 15:1598-1602.
30. Perez M, de La Torre JC. 2003. Characterization of the genomic promoter of the prototypic arenavirus lymphocytic choriomeningitis virus. J. Virol. 77:1184-1194.
31. Pinschewer DD, Perez M, de La Torre JC. 2005. Dual role of the lymphocytic choriomeningitis virus intergenic region in transcription termination and virus propagation. J. Virol. 79:4519-4526.
32. Pinschewer DD, Perez M, de La Torre JC. 2003. Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication. J. Virol. 77:3882-3887.
33. Polyak SJ, Zheng S, Harnish DG. 1995. 5= termini of Pichinde arenavirus S RNAs and mRNAs contain nontemplated nucleotides. J. Virol. 69:3211-3215.
34. Raju R, et al. 1990. Nontemplated bases at the 5= ends of Tacaribe virus mRNAs. Virology 174:53-59.
35. Sánchez AB, de La Torre JC. 2005. Genetic and biochemical evidence for an oligomeric structure of the functional L polymerase of the prototypic arenavirus lymphocytic choriomeningitis virus. J. Virol. 79:7262-7268.
36. Vezza AC, et al. 1978. Virion RNA species of the arenaviruses Pichinde, Tacaribe, and Tamiami. J. Virol. 26:485-497.
37. Yarnell WS. 1999. Mechanism of intrinsic transcription termination and antitermination. Science 284:611-615.
38. Zhou S, et al. 2010. Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus. J. Virol. 84:9452-9462