Postnatal Loss of Hap1 Reduces Hippocampal Neurogenesis and Causes Adult Depressive-Like Behavior in Mice

PLoS Genetics

Volumn 11, Issue 4, 2015, Pages

  Xiang, Jianxing ^a   Yan, Sen ^b   Li, Shi Hua ^a   Li, Xiao Jiang ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; HUNTINGTIN ASSOCIATED PROTEIN 1; IMIPRAMINE; PROTEIN; STEM CELL FACTOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; HAP1 PROTEIN, MOUSE; NERVE PROTEIN; STEM CELL FACTOR RECEPTOR;

ADENO ASSOCIATED VIRUS; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CELL CULTURE; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; FORCED SWIM TEST; GENE DELETION; GENETIC VARIABILITY; HEALTH; HIPPOCAMPUS; IMMOBILIZATION STRESS; LOCOMOTION; MAJOR DEPRESSION; MOOD; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INTERACTION; ROTAROD TEST; STEREOLOGY; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; THINKING; ANIMAL; C57BL MOUSE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOLOGY;

ADENO-ASSOCIATED VIRUS; MUS; RODENTIA;

ANIMALS; DEPRESSION; HIPPOCAMPUS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEUROGENESIS; PROTO-ONCOGENE PROTEINS C-KIT;

EID: 84930336220     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005175     Document Type: Article

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