Perfluorooctanoic Acid (PFOA)–induced Liver Lesions in Two Strains of Mice Following Developmental Exposures:PPARα Is Not Required

Toxicologic Pathology

Volumn 43, Issue 4, 2015, Pages 558-568

  Filgo, Adam J ^a,b   Quist, Erin M ^b,c   Hoenerhoff, Mark J ^b   Brix, Amy E ^d   Kissling, Grace E ^b   Fenton, Suzanne E ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

Author keywords

developmental exposure; liver; pathology; PFOA; PPAR ; tumor

Indexed keywords

PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; FLUOROCARBON; OCTANOIC ACID DERIVATIVE;

ANGIOSARCOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT HYPERPLASIA; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC CELL; HEPATOCELLULAR ADENOMA; HEPATOCELLULAR HYPERTROPHY; HISTIOCYTIC SARCOMA; HYPERPLASIA; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER TOXICITY; LYMPHOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; EXPERIMENTAL LIVER NEOPLASM; GENETICS; KNOCKOUT MOUSE; LIVER; MALE; METABOLISM; PATHOLOGY; PREGNANCY; PRENATAL EXPOSURE;

MUS; RODENTIA;

ANIMALS; CAPRYLATES; FEMALE; FLUOROCARBONS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, KNOCKOUT; PPAR ALPHA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84930321728     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623314558463     Document Type: Article

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