메뉴 건너뛰기




Volumn 360, Issue 3, 2015, Pages 583-589

Keratins and skin disease

Author keywords

Epidermolysis bullosa simplex; Genetics; Ichthyosis; Keratin; Pachyonychia; siRNA

Indexed keywords

CYTOKERATIN 1; CYTOKERATIN 10; CYTOKERATIN 14; CYTOKERATIN 16; CYTOKERATIN 17; CYTOKERATIN 2; CYTOKERATIN 5; CYTOKERATIN 6; CYTOKERATIN 71; CYTOKERATIN 74; CYTOKERATIN 75; CYTOKERATIN 81; CYTOKERATIN 83; CYTOKERATIN 86; KERATIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84930271250     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-014-2105-4     Document Type: Article
Times cited : (64)

References (49)
  • 1
    • 81255195853 scopus 로고    scopus 로고
    • Loss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients
    • COI: 1:CAS:528:DC%2BC3MXhs1Sjsr7L, PID: 22114688
    • Alam H, Gangadaran P, Bhate AV et al (2011) Loss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients. PLoS ONE 6:e27767. doi:10.1371/journal.pone.0027767
    • (2011) PLoS ONE , vol.6 , pp. e27767
    • Alam, H.1    Gangadaran, P.2    Bhate, A.V.3
  • 2
    • 67349222940 scopus 로고    scopus 로고
    • The molecular basis of human keratin disorders
    • COI: 1:CAS:528:DC%2BD1MXkslKgt7g%3D, PID: 19247691
    • Arin MJ (2009) The molecular basis of human keratin disorders. Hum Genet 125:355–73. doi:10.1007/s00439-009-0646-5
    • (2009) Hum Genet , vol.125 , pp. 355-373
    • Arin, M.J.1
  • 3
    • 80052865748 scopus 로고    scopus 로고
    • Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex
    • COI: 1:CAS:528:DC%2BC3MXhtFOlsLfM, PID: 21716320
    • Atkinson SD, McGilligan VE, Liao H et al (2011) Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex. J Invest Dermatol 131:2079–86. doi:10.1038/jid.2011.169
    • (2011) J Invest Dermatol , vol.131 , pp. 2079-2086
    • Atkinson, S.D.1    McGilligan, V.E.2    Liao, H.3
  • 4
    • 84897097836 scopus 로고    scopus 로고
    • Skin fragility and impaired desmosomal adhesion in mice lacking all keratins
    • PID: 24121403
    • Bär J, Kumar V, Roth W et al (2014) Skin fragility and impaired desmosomal adhesion in mice lacking all keratins. J Invest Dermatol 134:1012–22. doi:10.1038/jid.2013.416
    • (2014) J Invest Dermatol , vol.134 , pp. 1012-1022
    • Bär, J.1    Kumar, V.2    Roth, W.3
  • 5
    • 0026345962 scopus 로고
    • Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities
    • COI: 1:CAS:528:DyaK38Xls1KnsA%3D%3D, PID: 1720261
    • Bonifas JM, Rothman AL, Epstein EH (1991) Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities. Science 254:1202–5
    • (1991) Science , vol.254 , pp. 1202-1205
    • Bonifas, J.M.1    Rothman, A.L.2    Epstein, E.H.3
  • 6
    • 84862861973 scopus 로고    scopus 로고
    • Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells
    • COI: 1:CAS:528:DC%2BC38XhtVGltr%2FN, PID: 22344252
    • Busch T, Armacki M, Eiseler T et al (2012) Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells. J Cell Sci 125:2148–59. doi:10.1242/jcs.080127
    • (2012) J Cell Sci , vol.125 , pp. 2148-2159
    • Busch, T.1    Armacki, M.2    Eiseler, T.3
  • 7
    • 79952682059 scopus 로고    scopus 로고
    • Keratin gene mutations in disorders of human skin and its appendages
    • COI: 1:CAS:528:DC%2BC3MXjsVynu78%3D, PID: 21176769
    • Chamcheu JC, Siddiqui IA, Syed DN et al (2011) Keratin gene mutations in disorders of human skin and its appendages. Arch Biochem Biophys 508:123–37. doi:10.1016/j.abb.2010.12.019
    • (2011) Arch Biochem Biophys , vol.508 , pp. 123-137
    • Chamcheu, J.C.1    Siddiqui, I.A.2    Syed, D.N.3
  • 8
    • 84863104815 scopus 로고    scopus 로고
    • Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise
    • COI: 1:CAS:528:DC%2BC38XhtlantLzF, PID: 22716242
    • Chamcheu JC, Wood GS, Siddiqui IA et al (2012) Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise. Exp Dermatol 21:481–9. doi:10.1111/j.1600-0625.2012.01534.x
    • (2012) Exp Dermatol , vol.21 , pp. 481-489
    • Chamcheu, J.C.1    Wood, G.S.2    Siddiqui, I.A.3
  • 9
    • 77957371828 scopus 로고    scopus 로고
    • Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10
    • COI: 1:CAS:528:DC%2BC3cXht1WmtbbM, PID: 20798280
    • Choate KA, Lu Y, Zhou J et al (2010) Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10. Science 330:94–7
    • (2010) Science , vol.330 , pp. 94-97
    • Choate, K.A.1    Lu, Y.2    Zhou, J.3
  • 10
    • 0026662974 scopus 로고
    • Characterization and dynamics of O-linked glycosylation of human cytokeratin 8 and 18
    • COI: 1:CAS:528:DyaK38XhsVKnsb8%3D, PID: 1371281
    • Chou CF, Smith AJ, Omary MB (1992) Characterization and dynamics of O-linked glycosylation of human cytokeratin 8 and 18. J Biol Chem 267:3901–6
    • (1992) J Biol Chem , vol.267 , pp. 3901-3906
    • Chou, C.F.1    Smith, A.J.2    Omary, M.B.3
  • 11
    • 84882830710 scopus 로고    scopus 로고
    • Networking galore: intermediate filaments and cell migration
    • COI: 1:CAS:528:DC%2BC3sXhtFCqtrbM, PID: 23886476
    • Chung B-M, Rotty JD, Coulombe PA (2013) Networking galore: intermediate filaments and cell migration. Curr Opin Cell Biol 25:600–12. doi:10.1016/j.ceb.2013.06.008
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 600-612
    • Chung, B.-M.1    Rotty, J.D.2    Coulombe, P.A.3
  • 12
    • 0025861772 scopus 로고
    • Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses
    • COI: 1:CAS:528:DyaK3MXmslaitrY%3D, PID: 1717157
    • Coulombe PA, Hutton ME, Letai A et al (1991) Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Cell 66:1301–11
    • (1991) Cell , vol.66 , pp. 1301-1311
    • Coulombe, P.A.1    Hutton, M.E.2    Letai, A.3
  • 13
    • 0031684666 scopus 로고    scopus 로고
    • Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2
    • COI: 1:CAS:528:DyaK1cXmsV2mur8%3D, PID: 9767294
    • Covello SP, Smith FJ, Sillevis Smitt JH et al (1998) Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2. Br J Dermatol 139:475–80
    • (1998) Br J Dermatol , vol.139 , pp. 475-480
    • Covello, S.P.1    Smith, F.J.2    Sillevis Smitt, J.H.3
  • 14
    • 77957584091 scopus 로고    scopus 로고
    • Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin
    • COI: 1:CAS:528:DC%2BC3cXht1SltbnL, PID: 20871598
    • Depianto D, Kerns ML, Dlugosz AA, Coulombe PA (2010) Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet 42:910–4. doi:10.1038/ng.665
    • (2010) Nat Genet , vol.42 , pp. 910-914
    • Depianto, D.1    Kerns, M.L.2    Dlugosz, A.A.3    Coulombe, P.A.4
  • 15
    • 34247473917 scopus 로고    scopus 로고
    • Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts
    • COI: 1:CAS:528:DC%2BD2sXjvV2ms7s%3D, PID: 17416783
    • Dinkova-Kostova AT, Fahey JW, Wade KL et al (2007) Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol Biomarkers Prev 16:847–51. doi:10.1158/1055-9965.EPI-06-0934
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 847-851
    • Dinkova-Kostova, A.T.1    Fahey, J.W.2    Wade, K.L.3
  • 16
    • 84901242657 scopus 로고    scopus 로고
    • Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification
    • Fine JD, Bruckner-Tuderman L, Eady RA et al. (2014) Inherited epidermolysis bullosa: Updated recommendations on diagnosis and classification. J Am Acad Dermatol 1–24. doi: 10.1016/j.jaad.2014.01.903
    • (2014) J Am Acad Dermatol
    • Fine, J.D.1    Bruckner-Tuderman, L.2    Eady, R.A.3
  • 17
    • 84875726086 scopus 로고    scopus 로고
    • Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells
    • COI: 1:CAS:528:DC%2BC3sXmtFegsbY%3D, PID: 23241311
    • Fois G, Weimer M, Busch T et al (2013) Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells. FASEB J 27:1322–9. doi:10.1096/fj.12-215632
    • (2013) FASEB J , vol.27 , pp. 1322-1329
    • Fois, G.1    Weimer, M.2    Busch, T.3
  • 18
    • 79954602190 scopus 로고    scopus 로고
    • Genotype-phenotype correlations among pachyonychia congenita patients with K16 mutations
    • COI: 1:CAS:528:DC%2BC3MXks12iurw%3D, PID: 21160496
    • Fu T, Leachman SA, Wilson NJ et al (2011) Genotype-phenotype correlations among pachyonychia congenita patients with K16 mutations. J Invest Dermatol 131:1025–8. doi:10.1038/jid.2010.373
    • (2011) J Invest Dermatol , vol.131 , pp. 1025-1028
    • Fu, T.1    Leachman, S.A.2    Wilson, N.J.3
  • 19
    • 84894103604 scopus 로고    scopus 로고
    • Keratin 9 is required for the structural integrity and terminal differentiation of the palmoplantar epidermis
    • COI: 1:CAS:528:DC%2BC3sXhsFGjsLjE, PID: 23962810
    • Fu DJ, Thomson C, Lunny DP et al (2014) Keratin 9 is required for the structural integrity and terminal differentiation of the palmoplantar epidermis. J Invest Dermatol 134:754–63. doi:10.1038/jid.2013.356
    • (2014) J Invest Dermatol , vol.134 , pp. 754-763
    • Fu, D.J.1    Thomson, C.2    Lunny, D.P.3
  • 20
    • 84898655338 scopus 로고    scopus 로고
    • A novel non-sense mutation in keratin 10 causes a familial case of recessive epidermolytic ichthyosis
    • Gutierrez JA, Hannoush ZC, Vargas LG et al (2013) A novel non-sense mutation in keratin 10 causes a familial case of recessive epidermolytic ichthyosis. Mol Genet Genomic Med 1:108–112. doi:10.1002/mgg3.6
    • (2013) Mol Genet Genomic Med , vol.1 , pp. 108-112
    • Gutierrez, J.A.1    Hannoush, Z.C.2    Vargas, L.G.3
  • 21
    • 0032965997 scopus 로고    scopus 로고
    • Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation
    • COI: 1:STN:280:DyaK1M3ot1ajug%3D%3D, PID: 10354017
    • Irvine AD, McLean WH (1999) Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br J Dermatol 140:815–28
    • (1999) Br J Dermatol , vol.140 , pp. 815-828
    • Irvine, A.D.1    McLean, W.H.2
  • 22
    • 78651397689 scopus 로고    scopus 로고
    • Keratins in health and cancer: more than mere epithelial cell markers
    • COI: 1:CAS:528:DC%2BC3cXht1elu7%2FK, PID: 20890307
    • Karantza V (2011) Keratins in health and cancer: more than mere epithelial cell markers. Oncogene 30:127–38. doi:10.1038/onc.2010.456
    • (2011) Oncogene , vol.30 , pp. 127-138
    • Karantza, V.1
  • 23
    • 78650116927 scopus 로고    scopus 로고
    • Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia
    • COI: 1:CAS:528:DC%2BC3MXis1Omug%3D%3D, PID: 20926689
    • Kerns M, DePianto D, Yamamoto M, Coulombe PA (2010) Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia. Mol Biol Cell 21:4068–75. doi:10.1091/mbc.E10-02-0153
    • (2010) Mol Biol Cell , vol.21 , pp. 4068-4075
    • Kerns, M.1    DePianto, D.2    Yamamoto, M.3    Coulombe, P.A.4
  • 24
    • 77956412905 scopus 로고    scopus 로고
    • Cytoskeletal keratin glycosylation protects epithelial tissue from injury
    • COI: 1:CAS:528:DC%2BC3cXhtFSju7%2FK, PID: 20729838
    • Ku N-O, Toivola DM, Strnad P, Omary MB (2010) Cytoskeletal keratin glycosylation protects epithelial tissue from injury. Nat Cell Biol 12:876–85. doi:10.1038/ncb2091
    • (2010) Nat Cell Biol , vol.12 , pp. 876-885
    • Ku, N.-O.1    Toivola, D.M.2    Strnad, P.3    Omary, M.B.4
  • 25
    • 7944238356 scopus 로고    scopus 로고
    • Keratins and skin disorders
    • COI: 1:CAS:528:DC%2BD2cXhtVCgsrrN, PID: 15495218
    • Lane EB, McLean WHI (2004) Keratins and skin disorders. J Pathol 204:355–66. doi:10.1002/path.1643
    • (2004) J Pathol , vol.204 , pp. 355-366
    • Lane, E.B.1    McLean, W.H.I.2
  • 26
    • 0026545645 scopus 로고
    • A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering
    • COI: 1:CAS:528:DyaK38XitFahtrc%3D, PID: 1372711
    • Lane EB, Rugg EL, Navsaria H et al (1992) A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering. Nature 356:244–6. doi:10.1038/356244a0
    • (1992) Nature , vol.356 , pp. 244-246
    • Lane, E.B.1    Rugg, E.L.2    Navsaria, H.3
  • 27
    • 76349084709 scopus 로고    scopus 로고
    • First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder
    • COI: 1:CAS:528:DC%2BD1MXhsVGqs7bK, PID: 19935778
    • Leachman SA, Hickerson RP, Schwartz ME et al (2010) First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder. Mol Ther 18:442–6. doi:10.1038/mt.2009.273
    • (2010) Mol Ther , vol.18 , pp. 442-446
    • Leachman, S.A.1    Hickerson, R.P.2    Schwartz, M.E.3
  • 28
    • 84859785430 scopus 로고    scopus 로고
    • Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders
    • COI: 1:CAS:528:DC%2BC38Xhs1Gjurk%3D, PID: 22336941
    • Lessard JC, Coulombe PA (2012) Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders. J Invest Dermatol 132:1384–91. doi:10.1038/jid.2012.6
    • (2012) J Invest Dermatol , vol.132 , pp. 1384-1391
    • Lessard, J.C.1    Coulombe, P.A.2
  • 29
    • 84888354152 scopus 로고    scopus 로고
    • Keratin 16 regulates innate immunity in response to epidermal barrier breach
    • COI: 1:CAS:528:DC%2BC3sXhvFemurjJ, PID: 24218583
    • Lessard JC, Piña-Paz S, Rotty JD et al (2013) Keratin 16 regulates innate immunity in response to epidermal barrier breach. Proc Natl Acad Sci U S A 110:19537–42. doi:10.1073/pnas.1309576110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 19537-19542
    • Lessard, J.C.1    Piña-Paz, S.2    Rotty, J.D.3
  • 30
    • 84880465718 scopus 로고    scopus 로고
    • MMP-9 and CXCL8/IL-8 are potential therapeutic targets in epidermolysis bullosa simplex
    • COI: 1:CAS:528:DC%2BC3sXht1aju7jO, PID: 23894602
    • Lettner T, Lang R, Klausegger A et al (2013) MMP-9 and CXCL8/IL-8 are potential therapeutic targets in epidermolysis bullosa simplex. PLoS ONE 8:e70123. doi:10.1371/journal.pone.0070123
    • (2013) PLoS ONE , vol.8 , pp. e70123
    • Lettner, T.1    Lang, R.2    Klausegger, A.3
  • 31
    • 83155181586 scopus 로고    scopus 로고
    • Keratin disorders: from gene to therapy
    • COI: 1:CAS:528:DC%2BC3MXhtlyitL3K, PID: 21890491
    • McLean WHI, Moore CBT (2011) Keratin disorders: from gene to therapy. Hum Mol Genet 20:R189–97. doi:10.1093/hmg/ddr379
    • (2011) Hum Mol Genet , vol.20 , pp. R189-R197
    • McLean, W.H.I.1    Moore, C.B.T.2
  • 32
    • 79954570064 scopus 로고    scopus 로고
    • The phenotypic and molecular genetic features of pachyonychia congenita
    • COI: 1:CAS:528:DC%2BC3MXks12itL4%3D, PID: 21430705
    • McLean WHI, Hansen CD, Eliason MJ, Smith FJD (2011) The phenotypic and molecular genetic features of pachyonychia congenita. J Invest Dermatol 131:1015–7. doi:10.1038/jid.2011.59
    • (2011) J Invest Dermatol , vol.131 , pp. 1015-1017
    • McLean, W.H.I.1    Hansen, C.D.2    Eliason, M.J.3    Smith, F.J.D.4
  • 33
    • 77952700774 scopus 로고    scopus 로고
    • Revised nomenclature and classification of inherited ichthyoses: results of the first ichthyosis consensus conference in Sorèze 2009. J Am Acad Dermatol 63:607–41. doi:10.1016/j.jaad.2009.11.020
    • Oji V, Tadini G, Akiyama M et al (2010) Revised nomenclature and classification of inherited ichthyoses: results of the first ichthyosis consensus conference in Sorèze 2009. J Am Acad Dermatol 63:607–41. doi:10.1016/j.jaad.2009.11.020, Review
    • (2010) Review
    • Oji, V.1    Tadini, G.2    Akiyama, M.3
  • 34
    • 84911369491 scopus 로고    scopus 로고
    • Pachyonychia congenita cornered: report on the 11th annual international pachyonychia congenita consortium meeting. Br J Dermatol
    • O'Toole EA, Kaspar RL, Sprecher E et al (2014) Pachyonychia congenita cornered: report on the 11th annual international pachyonychia congenita consortium meeting. Br J Dermatol. doi:10.1111/bjd.13341
    • (2014) doi:10.1111/bjd.13341
    • O'Toole, E.A.1    Kaspar, R.L.2    Sprecher, E.3
  • 35
    • 84873731727 scopus 로고    scopus 로고
    • The expanding significance of keratin intermediate filaments in normal and diseased epithelia
    • COI: 1:CAS:528:DC%2BC38XhvV2rtrfJ, PID: 23270662
    • Pan X, Hobbs RP, Coulombe PA (2013) The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol 25:47–56. doi:10.1016/j.ceb.2012.10.018
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 47-56
    • Pan, X.1    Hobbs, R.P.2    Coulombe, P.A.3
  • 36
    • 84861184577 scopus 로고    scopus 로고
    • Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder
    • Pedrioli LMD, Fu DJ et al (2012) Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder. J Invest Dermatol 132:1627–35. doi:10.1038/jid.2012.28
    • (2012) J Invest Dermatol , vol.132 , pp. 1627-1635
    • Pedrioli, L.M.D.1    Fu, D.J.2
  • 37
    • 84877117144 scopus 로고    scopus 로고
    • A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ
    • PID: 23638377
    • Ramot Y, Sugawara K, Zákány N et al (2013) A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ. Peer J 1:e40. doi:10.7717/peerj.40
    • (2013) Peer J , vol.1 , pp. e40
    • Ramot, Y.1    Sugawara, K.2    Zákány, N.3
  • 38
    • 66749174066 scopus 로고    scopus 로고
    • Cytokines as genetic modifiers in K5−/− mice and in human epidermolysis bullosa simplex
    • COI: 1:CAS:528:DC%2BD1MXmtVymtLw%3D, PID: 19267394
    • Roth W, Reuter U, Wohlenberg C et al (2009) Cytokines as genetic modifiers in K5−/− mice and in human epidermolysis bullosa simplex. Hum Mutat 30:832–41. doi:10.1002/humu.20981
    • (2009) Hum Mutat , vol.30 , pp. 832-841
    • Roth, W.1    Reuter, U.2    Wohlenberg, C.3
  • 39
    • 33746097413 scopus 로고    scopus 로고
    • New consensus nomenclature for mammalian keratins
    • COI: 1:CAS:528:DC%2BD28XntFaqsb0%3D, PID: 16831889
    • Schweizer J, Bowden PE, Coulombe PA et al (2006) New consensus nomenclature for mammalian keratins. J Cell Biol 174:169–74. doi:10.1083/jcb.200603161
    • (2006) J Cell Biol , vol.174 , pp. 169-174
    • Schweizer, J.1    Bowden, P.E.2    Coulombe, P.A.3
  • 40
    • 84855351712 scopus 로고    scopus 로고
    • Congenital hair loss disorders: rare, but not too rare
    • COI: 1:CAS:528:DC%2BC38Xjt1Wltb0%3D, PID: 22044263
    • Shimomura Y (2012) Congenital hair loss disorders: rare, but not too rare. J Dermatol 39:3–10. doi:10.1111/j.1346-8138.2011.01395.x
    • (2012) J Dermatol , vol.39 , pp. 3-10
    • Shimomura, Y.1
  • 41
    • 0038326541 scopus 로고    scopus 로고
    • The molecular genetics of keratin disorders
    • PID: 12688839
    • Smith F (2003) The molecular genetics of keratin disorders. Am J Clin Dermatol 4:347–64
    • (2003) Am J Clin Dermatol , vol.4 , pp. 347-364
    • Smith, F.1
  • 42
    • 84894576158 scopus 로고    scopus 로고
    • Post-translational modifications of intermediate filament proteins: mechanisms and functions
    • COI: 1:CAS:528:DC%2BC2cXivFajurw%3D, PID: 24556839
    • Snider NT, Omary MB (2014) Post-translational modifications of intermediate filament proteins: mechanisms and functions. Nat Rev Mol Cell Biol 15:163–77. doi:10.1038/nrm3753
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 163-177
    • Snider, N.T.1    Omary, M.B.2
  • 43
    • 68149170036 scopus 로고    scopus 로고
    • New common variants affecting susceptibility to basal cell carcinoma
    • COI: 1:CAS:528:DC%2BD1MXotVCltrs%3D, PID: 19578363
    • Stacey SN, Sulem P, Masson G et al (2009) New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 41:909–14. doi:10.1038/ng.412
    • (2009) Nat Genet , vol.41 , pp. 909-914
    • Stacey, S.N.1    Sulem, P.2    Masson, G.3
  • 44
    • 0025284699 scopus 로고
    • The two-chain coiled-coil molecule of native epidermal keratin intermediate filaments is a type I-type II heterodimer
    • COI: 1:CAS:528:DyaK3cXktVahu7s%3D, PID: 1692836
    • Steinert PM (1990) The two-chain coiled-coil molecule of native epidermal keratin intermediate filaments is a type I-type II heterodimer. J Biol Chem 265:8766–74
    • (1990) J Biol Chem , vol.265 , pp. 8766-8774
    • Steinert, P.M.1
  • 45
    • 40549123948 scopus 로고    scopus 로고
    • The human intermediate filament database: comprehensive information on a gene family involved in many human diseases
    • COI: 1:CAS:528:DC%2BD1cXktlahsLs%3D, PID: 18033728
    • Szeverenyi I, Cassidy AJ, Chung CW et al (2008) The human intermediate filament database: comprehensive information on a gene family involved in many human diseases. Hum Mutat 29:351–60. doi:10.1002/humu.20652
    • (2008) Hum Mutat , vol.29 , pp. 351-360
    • Szeverenyi, I.1    Cassidy, A.J.2    Chung, C.W.3
  • 46
    • 84877068542 scopus 로고    scopus 로고
    • Topical diacerein for epidermolysis bullosa: a randomized controlled pilot study
    • PID: 23651789
    • Wally V, Kitzmueller S, Lagler F et al (2013) Topical diacerein for epidermolysis bullosa: a randomized controlled pilot study. Orphanet J Rare Dis 8:69. doi:10.1186/1750-1172-8-69
    • (2013) Orphanet J Rare Dis , vol.8 , pp. 69
    • Wally, V.1    Kitzmueller, S.2    Lagler, F.3
  • 47
    • 0022272929 scopus 로고
    • Intermediate filaments: structural conservation and divergence
    • COI: 1:CAS:528:DyaL28XmtVCrsLo%3D, PID: 2417512
    • Weber K, Geisler N (1985) Intermediate filaments: structural conservation and divergence. Ann N Y Acad Sci 455:126–43
    • (1985) Ann N Y Acad Sci , vol.455 , pp. 126-143
    • Weber, K.1    Geisler, N.2
  • 48
    • 85027925412 scopus 로고    scopus 로고
    • The molecular genetic analysis of the expanding pachyonychia congenita case collection
    • COI: 1:CAS:528:DC%2BC2cXhsVSrurvF, PID: 24611874
    • Wilson NJ, O'Toole EA, Milstone LM et al (2014) The molecular genetic analysis of the expanding pachyonychia congenita case collection. Br J Dermatol 171:343–55. doi:10.1111/bjd.12958
    • (2014) Br J Dermatol , vol.171 , pp. 343-355
    • Wilson, N.J.1    O'Toole, E.A.2    Milstone, L.M.3
  • 49
    • 79954882368 scopus 로고    scopus 로고
    • Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita
    • COI: 1:CAS:528:DC%2BC3MXks12itLo%3D, PID: 21390048
    • Zhao Y, Gartner U, Smith FJD, McLean WHI (2011) Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. J Invest Dermatol 131:1045–52. doi:10.1038/jid.2011.41
    • (2011) J Invest Dermatol , vol.131 , pp. 1045-1052
    • Zhao, Y.1    Gartner, U.2    Smith, F.J.D.3    McLean, W.H.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.