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Volumn 7, Issue 3, 2014, Pages 446-459

Network modeling approach to predict myofibroblast differentiation

Author keywords

Alpha smooth muscle actin ( SMA); Extracellular signaling related kinase (ERK); Fibroblast growth factor (FGF); Focal adhesion kinase (FAK); Integrin; p38; Src; Transforming growth factor beta (TGF 1)

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBROBLAST GROWTH FACTOR; FOCAL ADHESION KINASE; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE KINASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84930243042     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-014-0344-9     Document Type: Article
Times cited : (11)

References (49)
  • 2
    • 84868376130 scopus 로고    scopus 로고
    • Multiscale models of cell signaling
    • Bajikar, S. S., and K. A. Janes. Multiscale models of cell signaling. Ann. Biomed. Eng. 40(11):2319-2327, 2012.
    • (2012) Ann. Biomed. Eng. , vol.40 , Issue.11 , pp. 2319-2327
    • Bajikar, S.S.1    Janes, K.A.2
  • 3
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • DOI 10.1056/NEJM200005043421807
    • Blobe, G. C., W. P. Schiemann, and H. F. Lodish. Role of transforming growth factor beta in human disease. N. Engl. J. Med. 342(18):1350-1358, 2000. (Pubitemid 30408720)
    • (2000) New England Journal of Medicine , vol.342 , Issue.18 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 4
    • 10644246059 scopus 로고    scopus 로고
    • Evaluation of polydimethylsiloxane scaffolds with physiologically- relevant elastic moduli: Interplay of substrate mechanics and surface chemistry effects on vascular smooth muscle cell response
    • DOI 10.1016/j.biomaterials.2004.08.009, PII S0142961204007586
    • Brown, X. Q., K. Ookawa, and J. Y. Wong. Evaluation of polydimethylsiloxane scaffolds with physiologically-relevant elastic moduli: interplay of substrate mechanics and surface chemistry effects on vascular smooth muscle cell response. Biomaterials 26(16):3123-3129, 2005. (Pubitemid 39647247)
    • (2005) Biomaterials , vol.26 , Issue.16 , pp. 3123-3129
    • Brown, X.Q.1    Ookawa, K.2    Wong, J.Y.3
  • 6
    • 43049175154 scopus 로고    scopus 로고
    • TGF-beta1 targets the GSK-3beta/betacatenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts
    • Caraci, F., et al. TGF-beta1 targets the GSK-3beta/betacatenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. Pharmacol. Res. 57(4):274-282, 2008.
    • (2008) Pharmacol. Res. , vol.57 , Issue.4 , pp. 274-282
    • Caraci, F.1
  • 7
    • 7644238101 scopus 로고    scopus 로고
    • Amplification and oscillations in the FAK/Src kinase system during integrin signaling
    • DOI 10.1016/j.jtbi.2004.08.010, PII S0022519304003820
    • Caron-Lormier, G., and H. Berry. Amplification and oscillations in the FAK/Src kinase system during integrin signaling. J. Theor. Biol. 232(2):235-248, 2005. (Pubitemid 39458051)
    • (2005) Journal of Theoretical Biology , vol.232 , Issue.2 , pp. 235-248
    • Caron-Lormier, G.1    Berry, H.2
  • 8
    • 69549113276 scopus 로고    scopus 로고
    • FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin
    • Chan, M. W., et al. FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin. J. Cell Sci. 122(Pt 15):2769-2781, 2009.
    • (2009) J. Cell Sci. , vol.122 , Issue.PART 15 , pp. 2769-2781
    • Chan, M.W.1
  • 10
    • 55249089456 scopus 로고    scopus 로고
    • Focal adhesion kinase (FAK)-related nonkinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner
    • Ding, Q., et al. Focal adhesion kinase (FAK)-related nonkinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner. J. Biol. Chem. 283(40):26839-26849, 2008.
    • (2008) J. Biol. Chem. , vol.283 , Issue.40 , pp. 26839-26849
    • Ding, Q.1
  • 11
    • 0030969420 scopus 로고    scopus 로고
    • The effects of different corticosteroids on the healing colon anastomosis and cecum in a rat model
    • Eubanks, T. R., et al. The effects of different corticosteroids on the healing colon anastomosis and cecum in a rat model. Am. Surg. 63(3):266-269, 1997. (Pubitemid 27133253)
    • (1997) American Surgeon , vol.63 , Issue.3 , pp. 266-269
    • Eubanks, T.R.1    Greenberg, J.J.2    Dobrin, P.B.3    Harford, F.J.4    Gamelli, R.L.5
  • 12
    • 84861179304 scopus 로고    scopus 로고
    • Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts
    • Faust, D., et al. Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts. Cell Commun. Signal 10:6, 2012.
    • (2012) Cell Commun. Signal , vol.10 , pp. 6
    • Faust, D.1
  • 13
    • 59149097344 scopus 로고    scopus 로고
    • Mechanically activated integrin switch controls alpha5beta1 function
    • Friedland, J. C., M. H. Lee, and D. Boettiger. Mechanically activated integrin switch controls alpha5beta1 function. Science 323(5914):642-644, 2009.
    • (2009) Science , vol.323 , Issue.5914 , pp. 642-644
    • Friedland, J.C.1    Lee, M.H.2    Boettiger, D.3
  • 14
    • 33747086130 scopus 로고    scopus 로고
    • Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells
    • Galliher, A. J., and W. P. Schiemann. Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells. Breast Cancer Res. 8(4):R42, 2006.
    • (2006) Breast Cancer Res. , vol.8 , Issue.4
    • Galliher, A.J.1    Schiemann, W.P.2
  • 15
    • 34248584887 scopus 로고    scopus 로고
    • Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion
    • DOI 10.1158/0008-5472.CAN-06-3851
    • Galliher, A. J., and W. P. Schiemann. Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion. Cancer Res. 67(8):3752-3758, 2007. (Pubitemid 46762161)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3752-3758
    • Galliher, A.J.1    Schiemann, W.P.2
  • 16
    • 77956123956 scopus 로고    scopus 로고
    • Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture
    • Gilbert, P. M., et al. Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 329(5995):1078-1081, 2010.
    • (2010) Science , vol.329 , Issue.5995 , pp. 1078-1081
    • Gilbert, P.M.1
  • 17
    • 33845666103 scopus 로고    scopus 로고
    • FAK-dependent regulation of myofibroblast differentiation
    • Greenberg, R. S., et al. FAK-dependent regulation of myofibroblast differentiation. FASEB J. 20(7):1006-1008, 2006.
    • (2006) FASEB J. , vol.20 , Issue.7 , pp. 1006-1008
    • Greenberg, R.S.1
  • 18
    • 66949118241 scopus 로고    scopus 로고
    • Role of the MAPK/ERK pathway in valvular interstitial cell calcification
    • Gu, X., and K. S. Masters. Role of the MAPK/ERK pathway in valvular interstitial cell calcification. Am. J. Physiol. Heart Circ. Physiol. 296(6):H1748-H1757, 2009.
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.296 , Issue.6
    • Gu, X.1    Masters, K.S.2
  • 19
    • 38949102687 scopus 로고    scopus 로고
    • Analysis of mechanistic pathway models in drug discovery: P38 pathway
    • DOI 10.1021/bp070084g
    • Hendriks, B. S., F. Hua, and J. R. Chabot. Analysis of mechanistic pathway models in drug discovery: p38 pathway. Biotechnol. Prog. 24(1):96-109, 2008. (Pubitemid 351231254)
    • (2008) Biotechnology Progress , vol.24 , Issue.1 , pp. 96-109
    • Hendriks, B.S.1    Hua, F.2    Chabot, J.R.3
  • 20
    • 77957969256 scopus 로고    scopus 로고
    • Stretch-induced stress fiber remodeling and the activations of JNK and ERK depend on mechanical strain rate, but not FAK
    • Hsu, H. J., et al. Stretch-induced stress fiber remodeling and the activations of JNK and ERK depend on mechanical strain rate, but not FAK. PLoS ONE 5(8):e12470, 2010.
    • (2010) PLoS ONE , vol.5 , Issue.8
    • Hsu, H.J.1
  • 21
    • 84867398372 scopus 로고    scopus 로고
    • 5-HT(2B) antagonism arrests noncanonical TGF-beta1-induced valvular myofibroblast differentiation
    • Hutcheson, J. D., et al. 5-HT(2B) antagonism arrests noncanonical TGF-beta1-induced valvular myofibroblast differentiation. J. Mol. Cell. Cardiol. 53(5):707-714, 2012.
    • (2012) J. Mol. Cell. Cardiol. , vol.53 , Issue.5 , pp. 707-714
    • Hutcheson, J.D.1
  • 22
    • 84871778802 scopus 로고    scopus 로고
    • Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts
    • Hutcheson, J. D., et al. Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts. Arterioscler. Thromb. Vasc. Biol. 33(1):114-120, 2013.
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , Issue.1 , pp. 114-120
    • Hutcheson, J.D.1
  • 23
    • 0029120440 scopus 로고
    • Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
    • Ilic, D., et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377(6549):539-544, 1995.
    • (1995) Nature , vol.377 , Issue.6549 , pp. 539-544
    • Ilic, D.1
  • 24
    • 0033581478 scopus 로고    scopus 로고
    • Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail
    • Ivaska, J., et al. Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J. Cell Biol. 147(2):401-416, 1999.
    • (1999) J. Cell Biol. , vol.147 , Issue.2 , pp. 401-416
    • Ivaska, J.1
  • 25
    • 53749085729 scopus 로고    scopus 로고
    • Cytokine-induced signaling networks prioritize dynamic range over signal strength
    • Janes, K. A., H. C. Reinhardt, and M. B. Yaffe. Cytokine-induced signaling networks prioritize dynamic range over signal strength. Cell 135(2):343-354, 2008.
    • (2008) Cell , vol.135 , Issue.2 , pp. 343-354
    • Janes, K.A.1    Reinhardt, H.C.2    Yaffe, M.B.3
  • 26
    • 28844441230 scopus 로고    scopus 로고
    • Cell signaling: A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis
    • DOI 10.1126/science.1116598
    • Janes, K. A., et al. A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 310(5754):1646-1653, 2005. (Pubitemid 41780781)
    • (2005) Science , vol.310 , Issue.5754 , pp. 1646-1653
    • Janes, K.A.1    Albeck, J.G.2    Gaudet, S.3    Sorger, P.K.4    Lauffenburger, D.A.5    Yaffe, M.B.6
  • 27
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • DOI 10.1096/fj.06-7859rev
    • Junttila, M. R., S. P. Li, and J. Westermarck. Phosphatase-mediated crosstalk betweenMAPK signaling pathways in the regulation of cell survival. FASEB J. 22(4):954-965, 2008. (Pubitemid 351519953)
    • (2008) FASEB Journal , vol.22 , Issue.4 , pp. 954-965
    • Junttila, M.R.1    Li, S.-P.2    Westermarck, J.3
  • 28
    • 84873711465 scopus 로고    scopus 로고
    • Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip
    • Katsch, K., et al. Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip. Cell Commun. Signal. 10:5, 2012.
    • (2012) Cell Commun. Signal. , vol.10 , pp. 5
    • Katsch, K.1
  • 29
    • 3943087699 scopus 로고    scopus 로고
    • Basic fibroblast growth factor antagonizes transforming growth factor-beta1-induced smooth muscle gene expression through extracellular signal-regulated kinase 1/2 signaling pathway activation
    • DOI 10.1161/01.ATV.0000136548.17816.07
    • Kawai-Kowase, K., et al. Basic fibroblast growth factor antagonizes transforming growth factor-beta1-induced smooth muscle gene expression through extracellular signal-regulated kinase 1/2 signaling pathway activation. Arterioscler. Thromb. Vasc. Biol. 24(8):1384-1390, 2004. (Pubitemid 39050429)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.8 , pp. 1384-1390
    • Kawai-Kowase, K.1    Sato, H.2    Oyama, Y.3    Kanai, H.4    Sato, M.5    Doi, H.6    Kurabayashi, M.7
  • 30
    • 84856438793 scopus 로고    scopus 로고
    • Model simulations reveal VCAM-1 augment PAK activation rates to amplify p38 MAPK and VE-cadherin phosphorylation
    • Khanna, P., et al . Model simulations reveal VCAM-1 augment PAK activation rates to amplify p38 MAPK and VE-cadherin phosphorylation. Cell. Mol. Bioeng. 4(4):656-669, 2011.
    • (2011) Cell. Mol. Bioeng. , vol.4 , Issue.4 , pp. 656-669
    • Khanna, P.1
  • 31
    • 0033522510 scopus 로고    scopus 로고
    • Src family kinases are required for integrin but not PDGFR signal transduction
    • DOI 10.1093/emboj/18.9.2459
    • Klinghoffer, R. A., et al. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J. 18(9):2459-2471, 1999. (Pubitemid 29213279)
    • (1999) EMBO Journal , vol.18 , Issue.9 , pp. 2459-2471
    • Klinghoffer, R.A.1    Sachsenmaier, C.2    Cooper, J.A.3    Soriano, P.4
  • 33
    • 84857072845 scopus 로고    scopus 로고
    • Extracellular matrix elasticity modulates TGF-beta-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts
    • Meyer-ter-Vehn, T., et al. Extracellular matrix elasticity modulates TGF-beta-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts. Invest. Ophthalmol. Vis. Sci. 52(12):9149-9155, 2011.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , Issue.12 , pp. 9149-9155
    • Meyer-ter-Vehn, T.1
  • 35
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • DOI 10.1016/j.ceb.2006.08.011, PII S0955067406001220
    • Mitra, S. K., and D. D. Schlaepfer. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 18(5):516-523, 2006. (Pubitemid 44332916)
    • (2006) Current Opinion in Cell Biology , vol.18 , Issue.5 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 36
    • 45149106656 scopus 로고    scopus 로고
    • Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway
    • Pechkovsky, D. V., et al . Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. J. Biol. Chem. 283(19):12898-12908, 2008.
    • (2008) J. Biol. Chem. , vol.283 , Issue.19 , pp. 12898-12908
    • Pechkovsky, D.V.1
  • 37
    • 0028817908 scopus 로고
    • Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex
    • Plopper, G. E., et al. Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol. Biol. Cell 6(10):1349-1365, 1995.
    • (1995) Mol. Biol. Cell , vol.6 , Issue.10 , pp. 1349-1365
    • Plopper, G.E.1
  • 38
    • 70349496205 scopus 로고    scopus 로고
    • Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha (v)beta(3) and talin enable mechanotransduction
    • Roca-Cusachs, P., et al. Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha (v)beta(3) and talin enable mechanotransduction. Proc. Natl. Acad. Sci. USA 106(38):16245-16250, 2009.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.38 , pp. 16245-16250
    • Roca-Cusachs, P.1
  • 39
    • 84867185117 scopus 로고    scopus 로고
    • A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy
    • Sewell-Loftin, M. K., et al. A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy. J. Heart Valve Dis. 21(4):513-520, 2012.
    • (2012) J. Heart Valve Dis. , vol.21 , Issue.4 , pp. 513-520
    • Sewell-Loftin, M.K.1
  • 40
    • 84867377728 scopus 로고    scopus 로고
    • Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics
    • Shankaran, H., et al. Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics. Mol. BioSyst. 8(11):2868-2882, 2012.
    • (2012) Mol. BioSyst. , vol.8 , Issue.11 , pp. 2868-2882
    • Shankaran, H.1
  • 44
    • 33645754505 scopus 로고    scopus 로고
    • Signal processing in the TGF-beta superfamily ligand-receptor network
    • Vilar, J. M., R. Jansen, and C. Sander. Signal processing in the TGF-beta superfamily ligand-receptor network. PLoS Comput. Biol. 2(1):e3, 2006.
    • (2006) PLoS Comput. Biol. , vol.2 , Issue.1
    • Vilar, J.M.1    Jansen, R.2    Sander, C.3
  • 45
    • 4043127381 scopus 로고    scopus 로고
    • Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve disease
    • DOI 10.1161/01.RES.0000136520.07995.aa
    • Walker, G. A., et al. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ. Res. 95(3):253-260, 2004. (Pubitemid 39056285)
    • (2004) Circulation Research , vol.95 , Issue.3 , pp. 253-260
    • Walker, G.A.1    Masters, K.S.2    Shah, D.N.3    Anseth, K.S.4    Leinwand, L.A.5
  • 46
    • 0035955315 scopus 로고    scopus 로고
    • Uniaxial cyclic stretch induces focal adhesion kinase (FAK) tyrosine phosphorylation followed by mitogen-activated protein kinase (MAPK) activation
    • DOI 10.1006/bbrc.2001.5775
    • Wang, J. G., et al. Uniaxial cyclic stretch induces focal adhesion kinase (FAK) tyrosine phosphorylation followed by mitogen-activated protein kinase (MAPK) activation. Biochem. Biophys. Res. Commun. 288(2):356-361, 2001. (Pubitemid 33022491)
    • (2001) Biochemical and Biophysical Research Communications , vol.288 , Issue.2 , pp. 356-361
    • Wang, J.G.1    Miyazu, M.2    Matsushita, E.3    Sokabe, M.4    Naruse, K.5
  • 48
    • 70349509457 scopus 로고    scopus 로고
    • Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation
    • Watanabe, T., et al. Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation. Mol. Cancer Res. 7(9):1582-1592, 2009.
    • (2009) Mol. Cancer Res. , vol.7 , Issue.9 , pp. 1582-1592
    • Watanabe, T.1
  • 49
    • 38949115895 scopus 로고    scopus 로고
    • Integrin-mediated signalling through the MAP-kinase pathway
    • DOI 10.1049/iet-syb:20060058
    • Yee, K. L., V. M. Weaver, and D. A. Hammer. Integrin-mediated signalling through the MAP-kinase pathway. IET Syst. Biol. 2(1):8-15, 2008. (Pubitemid 351217538)
    • (2008) IET Systems Biology , vol.2 , Issue.1 , pp. 8-15
    • Yee, K.L.1    Weaver, V.M.2    Hammer, D.A.3


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