Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery

BMJ Open

Volumn 5, Issue 5, 2015, Pages

  Kertai, Miklos D ^a   Li, Yi Ju ^a   Li, Yen Wei ^a   Ji, Yunqi ^a   Alexander, John ^a,b   Newman, Mark F ^a,b   Smith, Peter K ^a   Joseph, Diane ^b   Mathew, Joseph P ^a   Podgoreanu, Mihai V ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE MB; BIOLOGICAL MARKER; CREATINE KINASE;

ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY BYPASS SURGERY; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PEROPERATIVE COMPLICATION; QUALITY CONTROL; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES; ADULT; ADVERSE EFFECTS; AGED; CARDIAC MUSCLE; GENOME-WIDE ASSOCIATION STUDY; INTRAOPERATIVE COMPLICATIONS; METABOLISM; MIDDLE AGED; MYOCARDIAL INFARCTION; PHYSIOLOGIC MONITORING; PROCEDURES; PROGNOSIS;

ADULT; AGED; BIOMARKERS; CORONARY ARTERY BYPASS; CREATINE KINASE; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTRAOPERATIVE COMPLICATIONS; MALE; MIDDLE AGED; MONITORING, PHYSIOLOGIC; MYOCARDIAL INFARCTION; MYOCARDIUM; PROGNOSIS;

EID: 84930226505     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2014-006920     Document Type: Article

References (40)

1. Domanski MJ, Mahaffey K, Hasselblad V, et al. Association of myocardial enzyme elevation and survival following coronary artery bypass graft surgery. JAMA 2011;305:585-91.
2. Schwartz Longacre L, Kloner RA, Arai AE, et al. New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation 2011;124:1172-9.
3. Samani NJ, Erdmann J, Hall AS, et al. Genomewide association analysis of coronary artery disease. N Engl J Med 2007;357:443-53.
4. McPherson R, Pertsemlidis A, Kavaslar N, et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007;316:1488-91.
5. Schunkert H, Gotz A, Braund P, et al. Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 2008;117:1675-84.
6. Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009;41:334-41.
7. Pankow JS, Folsom AR, Cushman M, et al. Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. Atherosclerosis 2001;154:681-9.
8. Liu KY, Muehlschlegel JD, Perry TE, et al. Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg 2010;139:483-8, 88 e1-2.
9. Muehlschlegel JD, Liu KY, Perry TE, et al. Chromosome 9p21 variant predicts mortality after coronary artery bypass graft surgery. Circulation 2010;122(11 Suppl):S60-5.
10. Collard CD, Shernan SK, Fox AA, et al. The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery. Circulation 2007;116(11 Suppl):I106-12.
11. Podgoreanu MV, White WD, Morris RW, et al. Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation 2006;114(1 Suppl):I275-81.
12. Lobato RL, White WD, Mathew JP, et al. Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses. Circulation 2011;124(11 Suppl):S143-8.
13. Luo L, Peng G, Zhu Y, et al. Genome-wide gene and pathway analysis. Eur J Hum Genet 2010;18:1045-53.
14. Torkamani A, Topol EJ, Schork NJ. Pathway analysis of seven common diseases assessed by genome-wide association. Genomics 2008;92:265-72.
15. Khoriaty R, Vasievich MP, Ginsburg D. The COPII pathway and hematologic disease. Blood 2012;120:31-8.
16. Little J, Higgins JP, Ioannidis JP, et al. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet 2009;125:131-51.
17. Skol AD, Scott LJ, Abecasis GR, et al. Optimal designs for two-stage genome-wide association studies. Genet Epidemiol 2007;31:776-88.
18. Alexander JH, Hafley G, Harrington RA, et al. Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. JAMA 2005;294:2446-54.
19. Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Circulation 2012;126:2020-35.
20. Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007;316:1491-3.
21. Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006;38:904-9.
22. Fox RM, Hanlon CD, Andrew DJ. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 2010;191:479-92.
23. Ahyi AN, Quinton LJ, Jones MR, et al. Roles of STAT3 in protein secretion pathways during the acute-phase response. Infect Immun 2013;81:1644-53.
24. Unlu G, Levic DS, Melville DB, et al. Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases. Int J Biochem Cell Biol 2014;47:57-67.
25. Baines AC, Adams EJ, Zhang B, et al. Disruption of the Sec24d gene results in early embryonic lethality in the mouse. PLoS ONE 2013;8:e61114.
26. Kluge A, Zimmermann R, Munkel B, et al. Insulin-like growth factor I is involved in inflammation linked angiogenic processes after microembolisation in porcine heart. Cardiovasc Res 1995;29:407-15.
27. Kluge A, Zimmermann R, Munkel B, et al. Insulin-like growth factor II is an experimental stress inducible gene in a porcine model of brief coronary occlusions. Cardiovasc Res 1995;29:708-16.
28. Vogt AM, Htun P, Kluge A, et al. Insulin-like growth factor-II delays myocardial infarction in experimental coronary artery occlusion. Cardiovasc Res 1997;33:469-77.
29. Heeschen C, Dimmeler S, Hamm CW, et al. Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis. J Am Coll Cardiol 2005;45:229-37.
30. Conti E, Andreotti F, Zuppi C. Pregnancy-associated plasma protein a as predictor of outcome in patients with suspected acute coronary syndromes. Circulation 2004;109:e211-12; author reply e11-2.
31. Granger A, Abdullah I, Huebner F, et al. Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. Faseb J 2008;22:3549-60.
32. Backs J, Olson EN. Control of cardiac growth by histone acetylation/deacetylation. Circ Res 2006;98:15-24.
33. Bujak M, Frangogiannis NG. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res 2007;74:184-95.
34. Kempf T, Eden M, Strelau J, et al. The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury. Circ Res 2006;98:351-60.
35. Lim CC, van Gaal WJ, Testa L, et al. With the "universal definition," measurement of creatine kinase-myocardial band rather than troponin allows more accurate diagnosis of periprocedural necrosis and infarction after coronary intervention. J Am Coll Cardiol 2011;57:653-61.
36. Virani SS, Brautbar A, Lee VV, et al. Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease. Circ J 2012;76:950-6.
37. Horne BD, Carlquist JF, Muhlestein JB, et al. Association of variation in the chromosome 9p21 locus with myocardial infarction versus chronic coronary artery disease. Circ Cardiovasc Genet 2008;1:85-92.
38. Chan K, Patel RS, Newcombe P, et al. Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol 2013;61:957-70.
39. Patel RS, Asselbergs FW, Quyyumi AA, et al. Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis. J Am Coll Cardiol 2014;63:2234-45.
40. de Lange F, Yoshitani K, Podgoreanu MV, et al. A novel survival model of cardioplegic arrest and cardiopulmonary bypass in rats: a methodology paper. J Cardiothorac Surg 2008;3:51.