An enhanced one-layer passive microfluidic mixer with an optimized lateral structure with the dean effect

Journal of Fluids Engineering, Transactions of the ASME

Volumn 137, Issue 9, 2015, Pages

  Zhou, Teng ^a   Xu, Yifan ^b   Liu, Zhenyu ^b   Joo, Sang Woo ^a  

^a Yeungnam University   (South Korea)

^b CHANGCHUN INSTITUTE OF OPTICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MIXING; REYNOLDS NUMBER;

BENT CHANNELS; BOOLEAN OPERATIONS; CONTRACTION EXPANSION; LATERAL STRUCTURES; MICROFLUIDIC MIXERS; MIXING EFFICIENCY; NUMERICAL RESULTS; TOPOLOGY OPTIMIZATION METHOD;

MIXERS (MACHINERY);

EID: 84930222021     PISSN: 00982202     EISSN: 1528901X     Source Type: Journal    
DOI: 10.1115/1.4030288     Document Type: Article

References (31)

1. Lee, C.-Y., Chang, C.-L., Wang, Y.-N., and Fu, L.-M., 2011, "Microfluidic Mixing: A Review," Int. J. Mol. Sci., 12(5), pp. 3263-3287.
2. Cartier, C. A., Drews, A. M., and Bishop, K. J. M., 2014, "Microfluidic Mixing of Nonpolar Liquids by Contact Charge Electrophoresis," Lab Chip, 14(21), pp. 4230-4236.
3. Afzal, A., and Kim, K.-Y., 2012, "Passive Split and Recombination Micromixer With Convergentcdivergent Walls," Chem. Eng. J., 203, pp. 182-192.
4. Ammar, H., Ouldel Moctar, A., Garnier, B., and Peerhossaini, H., 2014, "Flow Pulsation and Geometry Effects on Mixing of Two Miscible Fluids in Microchannels," ASME J. Fluids Eng., 136(12), p. 121101.
5. Karami, M., Shirani, E., Jarrahi, M., and Peerhossaini, H., 2014, "Mixing by Time-Dependent Orbits in Spatiotemporal Chaotic Advection," ASME J. Fluids Eng., 137(1), p. 011201.
6. Maki, A.-J., Hemmila, S., Hirvonen, J., Girish, N. N., Kreutzer, J., Hyttinen, J., and Kallio, P., 2014, "Modeling and Experimental Characterization of Pressure Drop in Gravity-Driven Microfluidic Systems," ASME J. Fluids Eng., 137(2), p. 021105.
7. Mohammadi, M., and Sharp, K. V., 2013, "Experimental Techniques for Bubble Dynamics Analysis in Microchannels: A Review," ASME J. Fluids Eng., 135(2), p. 021202.
8. Sen, A. K., and Bhardwaj, P., 2012, "Microfluidic System for Rapid Enumeration and Detection of Microparticles," ASME J. Fluids Eng., 134(11), p. 111401.
9. Solovitz, S. A., Zhao, J., Xue, W., and Xu, J., 2013, "Uniform Flow Control for a Multipassage Microfluidic Sensor," ASME J. Fluids Eng., 135(2), p. 021101.
10. Qian, S., and Bau, H. H., 2002, "A Chaotic Electroosmotic Stirrer," Anal. Chem., 74(15), pp. 3616-3625.
11. Qian, S., and Bau, H. H., 2005, "Magneto-Hydrodynamic Stirrer for Stationary and Moving Fluids," Sens. Actuators B, 106(2), pp. 859-870.
12. Liang, L., and Xuan, X., 2012, "Diamagnetic Particle Focusing Using Ferromicrofluidics With a Single Magnet," Microfluid. Nanofluid., 13(4), pp. 637-643.
13. Wen, C.-Y., Liang, K.-P., Chen, H., and Fu, L.-M., 2011, "Numerical Analysis of a Rapid Magnetic Microfluidic Mixer," Electrophoresis, 32(22), pp. 3268-3276.
14. Cardoso, V. F., Knoll, T., Velten, T., Rebouta, L., Mendes, P. M., Lanceros-Mendez, S., and Minas, G., 2014, "Polymer-Based Acoustic Streaming for Improving Mixing and Reaction Times in Microfluidic Applications," RSC Adv., 4(9), pp. 4292-4300.
15. SadAbadi, H., Packirisamy, M., and Wuthrich, R., 2013, "High Performance Cascaded pdms Micromixer Based on Split-and-Recombination Flows for Lab-On-A-Chip Applications," RSC Adv., 3(20), pp. 7296-7305.
16. Amini, H., Lee, W., and Di Carlo, D., 2014, "Inertial Microfluidic Physics," Lab Chip, 14(15), pp. 2739-2761.
17. Zhang, J., Li, W., Li, M., Alici, G., and Nguyen, N.-T., 2014, "Particle Inertial Focusing and Its Mechanism in a Serpentine Microchannel," Microfluid. Nanofluid., 17(2), pp. 305-316.
18. Amini, H., Sollier, E., Masaeli, M., Xie, Y., Ganapathysubramanian, B., Stone, H. A., and Di Carlo, D., 2013, "Engineering Fluid Flow Using Sequenced Microstructures," Nat. Commun., 4, p. 1826.
19. Lee, M. G., Choi, S., and Park, J.-K., 2009, "Rapid Laminating Mixer Using a Contraction-Expansion Array Microchannel," Appl. Phys. Lett., 95(5), p. 051902.
20. Lee, M. G., Choi, S., and Park, J.-K., 2010, "Rapid Multivortex Mixing in an Alternately Formed Contraction-Expansion Array Microchannel," Biomed. Microdevices, 12(6), pp. 1019-1026.
21. Lee, M. G., Choi, S., and Park, J. K., 2011, "Inertial Separation in a Contraction-Expansion Array Microchannel," J. Chromatogr. A, 1218(27), pp. 4138-4143.
22. Lee, M. G., Shin, J. H., Bae, C. Y., Choi, S., and Park, J.-K., 2013, "Label-Free Cancer Cell Separation From Human Whole Blood Using Inertial Microfluidics at Low Shear Stress," Anal. Chem., 85(13), pp. 6213-6218.
23. Liu, Z., Deng, Y., Lin, S., and Xuan, M., 2012, "Optimization of Micro Venturi Diode in Steady Flow at Low Reynolds Number," Eng. Optim., 44(11), pp. 1389-1404.
24. Deng, Y., Liu, Z., Zhang, P., Liu, Y., Gao, Q., and Wu, Y., 2012, "A Flexible Layout Design Method for Passive Micromixers," Biomed. Microdevices, 14(5), pp. 929-945.
25. Deng, Y., Zhang, P., Liu, Y., Wu, Y., and Liu, Z., 2013, "Optimization of Unsteady Incompressible Navier-Stokes Flows Using Variational Level Set Method," Int. J. Numer. Methods Fluids, 71(12), pp. 1475-1493.
26. Borrvall, T., and Petersson, J., 2003, "Topology Optimization of Fluids in Stokes Flow," Int. J. Numer. Methods Fluids, 41(1), pp. 77-107.
27. Gersborg-Hansen, A., Sigmund, O., and Haber, R. B., 2005, "Topology Optimization of Channel Flow Problems," Struct. Multidiscip. Optim., 30(3), pp. 181-192.
28. Olesen, L. H., Okkels, F., and Bruus, H., 2006, "A High-Level Programming-Language Implementation of Topology Optimization Applied to Steady-State Navier-Stokes Flow," Int. J. Numer. Methods Eng., 65(7), pp. 975-1001.
29. Donea, J., and Huerta, A., 2003, Finite Element Methods for Flow Problems, Wiley, Hoboken, NJ.
30. Deng, Y., Liu, Z., Zhang, P., Liu, Y., and Wu, Y., 2011, "Topology Optimization of Unsteady Incompressible Navier-Stokes Flows," J. Comput. Phys., 230(17), pp. 6688-6708.
31. Liu, Z., Gao, Q., Zhang, P., Xuan, M., and Wu, Y., 2011, "Topology Optimization of Fluid Channels With Flow Rate Equality Constraints," Struct. Multidiscip. Optim., 44(1), pp. 31-37.