Ginger (Zingiber officinale Roscoe) the dietary agent in skin care: A review

Bioactive Dietary Factors and Plant Extracts in Dermatology

Volumn , Issue , 2013, Pages 103-111

  Wilson, Rajesh ^a   Haniadka, Raghavendra ^a   Sandhya, Popuri ^b   Palatty, Princy Louis ^a   Baliga, Manjeshwar Shrinath ^a  

^a FATHER MULLER MEDICAL COLLEGE   (India)

^b Siddhartha Medical College   (India)

Author keywords

Ginger; Melanogenesis; Photo damage; Skin cancer; Zingiber officinale

Indexed keywords

EID: 84930159050     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-62703-167-7_11     Document Type: Chapter

References (30)

1. Vasala PA. Ginger. In: Peter KV, editor. Handbook of herbs and spices, vol. 1. Cambridge: Woodhead Publishing Ltd; 2004. p. 195-206.
2. Govindarajan VS. Ginger-chemistry, technology, and quality evaluation: part 1. Crit Rev Food Sci Nutr. 1982;17:1-96.
3. Govindarajan VS. Ginger-chemistry, technology, and quality evaluation: part 2. Crit Rev Food Sci Nutr. 1982;17:189-258.
4. Warrier PK. Spices in ayurveda. In: George CK, Sivadasan CR, Devakaran D, Sreekumari KP, editors. Strategies for export development of spices. Geneva: Spices Board, Cochin and International Trade Centre; 1989. p. 28.
5. Murray MT. The healing power of herbs: the enlightened person's guide to the wonders of medicinal plants. Rocklin, CA: Prima Publishing; 1995.
6. Bakhru HK. Herbs that heal: natural remedies for good health. Oriental paper backs. New Delhi: A Division of Vision Books Pvt. Ltd; 1999.
7. Baliga MS, Haniadka R, Pereira MM, et al. Update on the chemopreventive effects of ginger and its phytochemicals. Crit Rev Food Sci Nutr. 2011;51:499-523.
8. Juliani HR, Koroch AR, Simon JE, et al. Chemistry and quality of fresh ginger varieties ( Zingiber of fi cinale ) from Ghana. Acta Hortic (ISHS). 2007;756:399-406.
9. Ali BH, Blunden G, Tanira MO, et al. Some phytochemical, pharmacological and toxicological properties of ginger ( Zingiber of fi cinale Roscoe): a review of recent research. Food Chem Toxicol. 2008;46:409-20.
10. Nigam N, Bhui K, Prasad S, et al. [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. Chem Biol Interact. 2009;181:77-84.
11. Shukla Y, Singh M. Cancer preventive properties of ginger: a brief review. Food Chem Toxicol. 2007;45:683-90.
12. Chrubasik S, Pittler MH, Roufogalis BD. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine. 2005;12:684-701.
13. Tsukahara K, Nakagawa H, Moriwaki S, et al. Inhibition of ultraviolet-B-induced wrinkle formation by an elastaseinhibiting herbal extract: implication for the mechanism underlying elastase-associated wrinkles. Int J Dermatol. 2006;45:460-8.
14. Guahk GH, Ha SK, Jung HS, et al. Zingiber of fi cinale protects HaCaT cells and C57BL/6 mice from ultraviolet B-induced in fl ammation. J Med Food. 2010;13:673-80.
15. Kim JK, Kim Y, Na KM, et al. [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radic Res. 2007;41:603-14.
16. Kornhauser A, Coelho SG, Hearing VJ. Applications of hydroxy acids: classi fi cation, mechanisms, and photoactivity. Clin Cosmet Investig Dermatol. 2010;3:135-42.
17. Huang HC, Chiu SH, Chang TM. Inhibitory effect of [6]-gingerol on melanogenesis in B16F10 melanoma cells and a possible mechanism of action. Biosci Biotechnol Biochem. 2011;75:1067-72.
18. Katiyar SK, Agarwal R, Mukhtar H. Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber of fi cinale rhizome. Cancer Res. 1996;56:1023-30.
19. Tjeerdsma F, Jonkman MF, Spoo JR. Temporary arrest of basal cell carcinoma formation in a patient with basal cell naevus syndrome (BCNS) since treatment with a gel containing various plant extracts. J Eur Acad Dermatol Venereol. 2011;25:244-5.
20. Surh YJ, Park KK, Chun KS, et al. Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger. J Environ Pathol Toxicol Oncol. 1999;18:131-9.
21. Nigam N, George J, Srivastava S, et al. Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis. Cancer Chemother Pharmacol. 2010;65:687-96.
22. Bode AM, Ma WY, Surh YJ, et al. Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol. Cancer Res. 2001;61:850-3.
23. Park KK, Chun KS, Lee JM, et al. Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced in fl ammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice. Cancer Lett. 1998;129:139-44.
24. Kim SO, Chun KS, Kundu JK, et al. Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kappaB and p38 MAPK in mouse skin. Biofactors. 2004;21:27-31.
25. Kim SO, Kundu JK, Shin YK, et al. [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin. Oncogene. 2005;24:2558-67.
26. Wu H, Hsieh MC, Lo CY, et al. 6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice. Mol Nutr Food Res. 2010;54:1296-306.
27. Pan MH, Hsieh MC, Hsu PC, et al. 6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. Mol Nutr Food Res. 2008;52:1467-77.
28. Murakami A, Tanaka T, Lee JY, et al. Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice. Int J Cancer. 2004;110:481-90.
29. Shin JW, Ohnishi K, Murakami A, et al. Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2. Cancer Prev Res (Phila). 2011;4:860-70.
30. Nakamura Y, Yoshida C, Murakami A, et al. Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett. 2004;572:245-50.