-
1
-
-
33748328199
-
Survival benefit associated with human anti-mouse antibody (HAMA) in patients with B-cell malignancies
-
Azinovic I, DeNardo GL, Lamborn KR, Mirick G, Goldstein D, Bradt BM, DeNardo SJ (2006) Survival benefit associated with human anti-mouse antibody (HAMA) in patients with B-cell malignancies. Cancer Immunol Immunother 55:1451-1458
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 1451-1458
-
-
Azinovic, I.1
Denardo, G.L.2
Lamborn, K.R.3
Mirick, G.4
Goldstein, D.5
Bradt, B.M.6
Denardo, S.J.7
-
2
-
-
33947383745
-
Identification and removal of immunogenicity in therapeutic proteins
-
Baker MP, Jones TD (2007) Identification and removal of immunogenicity in therapeutic proteins. Curr Opin Drug Discov Dev 10:219-227
-
(2007)
Curr Opin Drug Discov Dev
, vol.10
, pp. 219-227
-
-
Baker, M.P.1
Jones, T.D.2
-
3
-
-
0037452779
-
Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology
-
Bard F, Barbour R, Cannon C, Carretto R, Fox M, Games D, Guido T, Hoenow K, Hu K, Johnson-Wood K et al (2003) Epitope and isotype specificities of antibodies to beta-amyloid peptide for protection against Alzheimer's disease-like neuropathology. Proc Natl Acad Sci USA 100:2023-2028
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2023-2028
-
-
Bard, F.1
Barbour, R.2
Cannon, C.3
Carretto, R.4
Fox, M.5
Games, D.6
Guido, T.7
Hoenow, K.8
Hu, K.9
Johnson-Wood, K.10
-
4
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K et al (2000) Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 6:916-919
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
-
5
-
-
33846144397
-
Immunoge-nicity, efficacy and adverse events of adalimumab in RA patients
-
Bender NK, Heilig CE, Droll B, Wohlgemuth J, Armbruster FP, Heilig B (2007) Immunoge-nicity, efficacy and adverse events of adalimumab in RA patients. Rheumatol Int 27:269-274
-
(2007)
Rheumatol Int
, vol.27
, pp. 269-274
-
-
Bender, N.K.1
Heilig, C.E.2
Droll, B.3
Wohlgemuth, J.4
Armbruster, F.P.5
Heilig, B.6
-
6
-
-
47949132196
-
Active and passive immunotherapy for neurodegenerative disorders
-
Brody DL, Holtzman DM (2008) Active and passive immunotherapy for neurodegenerative disorders. Annu Rev Neurosci 31:175-193
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 175-193
-
-
Brody, D.L.1
Holtzman, D.M.2
-
7
-
-
34548060582
-
Pharmacogenetics of anti-TNF treatment in patients with rheumatoid arthritis
-
Coenen MJ, Toonen EJ, Scheffer H, Radstake TR, Barrera P, Franke B (2007) Pharmacogenetics of anti-TNF treatment in patients with rheumatoid arthritis. Pharmacogenomics 8:761-773
-
(2007)
Pharmacogenomics
, vol.8
, pp. 761-773
-
-
Coenen, M.J.1
Toonen, E.J.2
Scheffer, H.3
Radstake, T.R.4
Barrera, P.5
Franke, B.6
-
8
-
-
0029835023
-
INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group
-
Cohen J, Carlet J (1996) INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group. Crit Care Med 24:1431-1440
-
(1996)
Crit Care Med
, vol.24
, pp. 1431-1440
-
-
Cohen, J.1
Carlet, J.2
-
10
-
-
54049088585
-
Activation of natural regulatory T cells by IgG Fc-derived peptide "tregitopes"
-
De Groot AS, Moise L, McMurry JA, Wambre E, Van Overtvelt L, Moingeon P, Scott DW, Martin W (2008) Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes". Blood 112:3303-3311
-
(2008)
Blood
, vol.112
, pp. 3303-3311
-
-
De Groot, A.S.1
Moise, L.2
McMurry, J.A.3
Wambre, E.4
Van Overtvelt, L.5
Moingeon, P.6
Scott, D.W.7
Martin, W.8
-
11
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM (2001) Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 98:8850-8855
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8850-8855
-
-
Demattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
Holtzman, D.M.6
-
12
-
-
77953677314
-
Immunotoxicity of monoclonal antibodies
-
Descotes J (2009) Immunotoxicity of monoclonal antibodies. MAbs 1:104-111
-
(2009)
MAbs
, vol.1
, pp. 104-111
-
-
Descotes, J.1
-
13
-
-
0035093479
-
Omalizumab
-
discussion 261
-
Easthope S, Jarvis B (2001) Omalizumab. Drugs 61:253-260 discussion 261
-
(2001)
Drugs
, vol.61
, pp. 253-260
-
-
Easthope, S.1
Jarvis, B.2
-
14
-
-
36348937220
-
Biosimilar drugs: Concerns and opportunities
-
Genazzani AA, Biggio G, Caputi AP, Del Tacca M, Drago F, Fantozzi R, Canonico PL (2007) Biosimilar drugs: concerns and opportunities. Biodrugs 21:351-356
-
(2007)
Biodrugs
, vol.21
, pp. 351-356
-
-
Genazzani, A.A.1
Biggio, G.2
Caputi, A.P.3
Del Tacca, M.4
Drago, F.5
Fantozzi, R.6
Canonico, P.L.7
-
16
-
-
33747855481
-
Comparing antibody and small-molecule therapies for cancer
-
Imai K, Takaoka A (2006) Comparing antibody and small-molecule therapies for cancer. Nat Rev Cancer 6:714-727
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 714-727
-
-
Imai, K.1
Takaoka, A.2
-
17
-
-
67349088299
-
How to systematically evaluate immunogenicity of therapeutic proteins-regulatory considerations
-
Jahn EM, Schneider CK (2009) How to systematically evaluate immunogenicity of therapeutic proteins-regulatory considerations. N Biotechnol 25:280-286
-
(2009)
N Biotechnol
, vol.25
, pp. 280-286
-
-
Jahn, E.M.1
Schneider, C.K.2
-
18
-
-
79959700509
-
Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer
-
Junttila TT, Li G, Parsons K, Phillips GL, Sliwkowski MX (2010) Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer. Breast Cancer Res Treat 128:347-356
-
(2010)
Breast Cancer Res Treat
, vol.128
, pp. 347-356
-
-
Junttila, T.T.1
Li, G.2
Parsons, K.3
Phillips, G.L.4
Sliwkowski, M.X.5
-
20
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495-497
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
21
-
-
38449088277
-
Antibody-based approaches in Alzheimer's research: Safety, pharmacokinetics, metabolism, and analytical tools
-
Lichtlen P, Mohajeri MH (2008) Antibody-based approaches in Alzheimer's research: safety, pharmacokinetics, metabolism, and analytical tools. J Neurochem 104:859-874
-
(2008)
J Neurochem
, vol.104
, pp. 859-874
-
-
Lichtlen, P.1
Mohajeri, M.H.2
-
22
-
-
78650578346
-
Acute infusion reactions induced by monoclonal antibody therapy
-
Maggi E, Vultaggio A, Matucci A (2011) Acute infusion reactions induced by monoclonal antibody therapy. Expert Rev Clin Immunol 7:55-63
-
(2011)
Expert Rev Clin Immunol
, vol.7
, pp. 55-63
-
-
Maggi, E.1
Vultaggio, A.2
Matucci, A.3
-
23
-
-
78650210590
-
Immunotherapy for Alzheimer's disease
-
Morgan D (2011) Immunotherapy for Alzheimer's disease. J Int Med 269:54-63
-
(2011)
J Int Med
, vol.269
, pp. 54-63
-
-
Morgan, D.1
-
24
-
-
77957361348
-
Development trends for human monoclonal antibody therapeutics
-
Nelson AL, Dhimolea E, Reichert JM (2010) Development trends for human monoclonal antibody therapeutics. Nat Rev Drug Discov 9:767-774
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 767-774
-
-
Nelson, A.L.1
Dhimolea, E.2
Reichert, J.M.3
-
25
-
-
78651389288
-
XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases
-
Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L (2011) XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases. MAbs 3:49-60
-
(2011)
MAbs
, vol.3
, pp. 49-60
-
-
Owyang, A.M.1
Issafras, H.2
Corbin, J.3
Ahluwalia, K.4
Larsen, P.5
Pongo, E.6
Handa, M.7
Horwitz, A.H.8
Roell, M.K.9
Haak-Frendscho, M.10
Masat, L.11
-
26
-
-
0036734997
-
Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide
-
Pan W, Solomon B, Maness LM, Kastin AJ (2002) Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide. Exp Biol Med (Maywood) 227:609-615
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, pp. 609-615
-
-
Pan, W.1
Solomon, B.2
Maness, L.M.3
Kastin, A.J.4
-
27
-
-
78651387929
-
Antibody-based therapeutics to watch in 2011
-
Reichert JM (2011) Antibody-based therapeutics to watch in 2011. MAbs 3:76-99
-
(2011)
MAbs
, vol.3
, pp. 76-99
-
-
Reichert, J.M.1
-
28
-
-
15844367464
-
Immunologic mechanisms of EPO-associated pure red cell aplasia
-
Schellekens H (2005) Immunologic mechanisms of EPO-associated pure red cell aplasia. Best Pract Res Clin Haematol 18:473-480
-
(2005)
Best Pract Res Clin Haematol
, vol.18
, pp. 473-480
-
-
Schellekens, H.1
-
29
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K et al (1999) Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400:173-177
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
-
30
-
-
0035081475
-
Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
Selkoe DJ (2001) Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 3:75-80
-
(2001)
J Alzheimers Dis
, vol.3
, pp. 75-80
-
-
Selkoe, D.J.1
-
31
-
-
77951086901
-
Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease
-
Siemers ER, Friedrich S, Dean RA, Gonzales CR, Farlow MR, Paul SM, Demattos RB (2010) Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease. Clin Neuropharmacol 33:67-73
-
(2010)
Clin Neuropharmacol
, vol.33
, pp. 67-73
-
-
Siemers, E.R.1
Friedrich, S.2
Dean, R.A.3
Gonzales, C.R.4
Farlow, M.R.5
Paul, S.M.6
Demattos, R.B.7
-
33
-
-
0034680852
-
Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization
-
Steinberger P, Sutton JK, Rader C, Elia M, Barbas CF 3rd (2000) Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization. J Biol Chem 275:36073-36078
-
(2000)
J Biol Chem
, vol.275
, pp. 36073-36078
-
-
Steinberger, P.1
Sutton, J.K.2
Rader, C.3
Elia, M.4
Barbas Iii., C.F.5
-
34
-
-
70449727004
-
Optimization of Fc-mediated effector functions of monoclonal antibodies
-
Strohl WR (2009) Optimization of Fc-mediated effector functions of monoclonal antibodies. Curr Opin Biotechnol 20:685-691
-
(2009)
Curr Opin Biotechnol
, vol.20
, pp. 685-691
-
-
Strohl, W.R.1
-
35
-
-
61649112477
-
Translational strategies for development of monoclonal antibodies from discovery to the clinic
-
Tabrizi MA, Bornstein GG, Klakamp SL, Drake A, Knight R, Roskos L (2009) Translational strategies for development of monoclonal antibodies from discovery to the clinic. Drug Discov Today 14:298-305
-
(2009)
Drug Discov Today
, vol.14
, pp. 298-305
-
-
Tabrizi, M.A.1
Bornstein, G.G.2
Klakamp, S.L.3
Drake, A.4
Knight, R.5
Roskos, L.6
-
36
-
-
13844312947
-
Humanization of a chicken anti-IL-12 monoclonal antibody
-
Tsurushita N, Park M, Pakabunto K, Ong K, Avdalovic A, Fu H, Jia A, Vasquez M, Kumar S (2004) Humanization of a chicken anti-IL-12 monoclonal antibody. J Immunol Methods 295:9-19
-
(2004)
J Immunol Methods
, vol.295
, pp. 9-19
-
-
Tsurushita, N.1
Park, M.2
Pakabunto, K.3
Ong, K.4
Avdalovic, A.5
Fu, H.6
Jia, A.7
Vasquez, M.8
Kumar, S.9
-
37
-
-
59149104037
-
General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold
-
Vincke C, Loris R, Saerens D, Martinez-Rodriguez S, Muyldermans S, Conrath K (2009) General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J Biol Chem 284:3273-3284
-
(2009)
J Biol Chem
, vol.284
, pp. 3273-3284
-
-
Vincke, C.1
Loris, R.2
Saerens, D.3
Martinez-Rodriguez, S.4
Muyldermans, S.5
Conrath, K.6
-
38
-
-
33846140780
-
Antibody structure, instability, and formulation
-
Wang W, Singh S, Zeng DL, King K, Nema S (2007) Antibody structure, instability, and formulation. J Pharm Sci 96:1-26
-
(2007)
J Pharm Sci
, vol.96
, pp. 1-26
-
-
Wang, W.1
Singh, S.2
Zeng, D.L.3
King, K.4
Nema, S.5
-
39
-
-
79952450499
-
The safety of using anti-VEGF: Is there strength in numbers?
-
Wong D, Joussen AM (2010) The safety of using anti-VEGF: is there strength in numbers? Graefes Arch Clin Exp Ophthalmol 249:161-162
-
(2010)
Graefes Arch Clin Exp Ophthalmol
, vol.249
, pp. 161-162
-
-
Wong, D.1
Joussen, A.M.2
-
40
-
-
34047143155
-
Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract
-
Wu H, Pfarr DS, Johnson S, Brewah YA, Woods RM, Patel NK, White WI, Young JF, Kiener PA (2007) Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract. J Mol Biol 368:652-665
-
(2007)
J Mol Biol
, vol.368
, pp. 652-665
-
-
Wu, H.1
Pfarr, D.S.2
Johnson, S.3
Brewah, Y.A.4
Woods, R.M.5
Patel, N.K.6
White, W.I.7
Young, J.F.8
Kiener, P.A.9
|