Attenuation of cartilage pathogenesis in post-traumatic osteoarthritis (PTOA) in mice by blocking the stromal derived factor 1 receptor (CXCR4) with the specific inhibitor, AMD3100

Journal of Orthopaedic Research

Volumn 33, Issue 7, 2015, Pages 1071-1078

  Thomas, Nathan P ^a   Li, Pengcui ^a,b   Fleming, Braden C ^a   Chen, Qian ^a   Wei, Xiaochun ^b   Xiao Hua, Pan ^c   Li, Gang ^d   Wei, Lei ^a,b  

^a BROWN UNIVERSITY   (United States)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

articular cartilage; FMT; osteoarthritis; SDF 1

Indexed keywords

CATHEPSIN B; CATHEPSIN L; CATHEPSIN S; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGEN TYPE 3; COLLAGEN TYPE 4; COLLAGENASE 3; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; FLUORESCENT DYE; HETEROCYCLIC COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FLUORESCENCE MOLECULAR TOMOGRAPHY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KNEE MENISCUS; KNEE OSTEOARTHRITIS; MALE; MOUSE; MOUSE MODEL; NONHUMAN; OSMOTIC MINIPUMP; PATHOGENESIS; POSTTRAUMATIC ARTHROPATHY; POSTTRAUMATIC OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TOMOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COMPLICATION; DRUG SCREENING; KNEE INJURY; OSTEOARTHRITIS, KNEE; PATHOLOGY; RANDOMIZATION;

ANIMALS; CARTILAGE, ARTICULAR; DRUG EVALUATION, PRECLINICAL; FLUORESCENT DYES; HETEROCYCLIC COMPOUNDS; IMMUNOHISTOCHEMISTRY; KNEE INJURIES; MALE; MICE, INBRED C57BL; OSTEOARTHRITIS, KNEE; RANDOM ALLOCATION; RECEPTORS, CXCR4; TOMOGRAPHY;

EID: 84930086942     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22862     Document Type: Article

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