메뉴 건너뛰기




Volumn 79, Issue 6, 2015, Pages 1342-1348

Acute effects of Rho-kinase inhibitor fasudil on pulmonary arterial hypertension in patients with congenital heart defects

Author keywords

Congenital heart defect; Fasudil; Hemodynamics; Pulmonary arterial hypertension; Rho kinase inhibitor

Indexed keywords

FASUDIL; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; PROTEIN KINASE INHIBITOR; RHO KINASE; VASODILATOR AGENT;

EID: 84930060994     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-14-1015     Document Type: Article
Times cited : (31)

References (24)
  • 2
    • 77955953602 scopus 로고    scopus 로고
    • Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension
    • Humbert M, Sitbon O, Yaici A, Montani D, O’Callaghan DS, Jais X, et al. Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension. Eur Respir J 2010; 36: 549-555.
    • (2010) Eur Respir J , vol.36 , pp. 549-555
    • Humbert, M.1    Sitbon, O.2    Yaici, A.3    Montani, D.4    O’Callaghan, D.S.5    Jais, X.6
  • 3
    • 77954759389 scopus 로고    scopus 로고
    • Predicting survival in pulmonary arterial hypertension: In-sights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management (reveal)
    • Benza RL, Miller DP, Gomberg-Maitland M, Frantz RP, Foreman AJ, Coffey CS, et al. Predicting survival in pulmonary arterial hypertension: In-sights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL). Circulation 2010; 122: 164-172.
    • (2010) Circulation , vol.122 , pp. 164-172
    • Benza, R.L.1    Miller, D.P.2    Gomberg-Maitland, M.3    Frantz, R.P.4    Foreman, A.J.5    Coffey, C.S.6
  • 6
    • 84884615008 scopus 로고    scopus 로고
    • A new class of drug for pulmonary arterial hypertension: Can a rho-kinase inhibitor break the stagnation in treating it?
    • Miyagawa K, Emoto N. A new class of drug for pulmonary arterial hypertension: Can a Rho-kinase inhibitor break the stagnation in treating it? Circ J 2013; 77: 2477-2478.
    • (2013) Circ J , vol.77 , pp. 2477-2478
    • Miyagawa, K.1    Emoto, N.2
  • 7
    • 0036182417 scopus 로고    scopus 로고
    • Rho-kinase as a novel therapeutic target in treatment of cardiovascular disease
    • Shimokawa H. Rho-kinase as a novel therapeutic target in treatment of cardiovascular disease. J Cardiovasc Pharmacol 2002; 39: 319-327.
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 319-327
    • Shimokawa, H.1
  • 8
    • 27644505297 scopus 로고    scopus 로고
    • Effects of fasudil in acute ischemic stroke: Results of a prospective placebo-controlled double-blind trial
    • Masato S, Shunsaku H, Minoru S, Shin-ichi S, Eiichi O, for the Fasudil Ischemic Stroke Study Group. Effects of fasudil in acute ischemic stroke: Results of a prospective placebo-controlled double-blind trial. J Neurol Sci 2005; 238: 31-39.
    • (2005) J Neurol Sci , vol.238 , pp. 31-39
    • Masato, S.1    Shunsaku, H.2    Minoru, S.3    Shin-Ichi, S.4    Eiichi, O.5
  • 9
    • 31644431508 scopus 로고    scopus 로고
    • Beneficial acute effects of rho kinase inhibitor in patients with pul monary arterial hypertension
    • Ishikura K, Yamada N, Ito M, Ota S, Nakamura M, Isaka N, et al. Beneficial acute effects of Rho kinase inhibitor in patients with pul monary arterial hypertension. Circ J 2006; 70: 174-178.
    • (2006) Circ J , vol.70 , pp. 174-178
    • Ishikura, K.1    Yamada, N.2    Ito, M.3    Ota, S.4    Nakamura, M.5    Isaka, N.6
  • 10
    • 77950921360 scopus 로고    scopus 로고
    • Acute vasodilator effects of inhaled fasudil, a specific rho-kinase inhibitor, in patients with pulmonary arterial hypertension
    • Fujita H, Fukumoto Y, Saji K, Sugimura K, Demachi J, Nawata J, et al. Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension. Heart Vessels 2010; 25: 144-149.
    • (2010) Heart Vessels , vol.25 , pp. 144-149
    • Fujita, H.1    Fukumoto, Y.2    Saji, K.3    Sugimura, K.4    Demachi, J.5    Nawata, J.6
  • 11
    • 64249097973 scopus 로고    scopus 로고
    • Acute inhibition of rho-kinase attenuates pulmonary hypertension in patients with congenital heart disease
    • Li F, Xia W, Yuan S, Sun R. Acute inhibition of Rho-kinase attenuates pulmonary hypertension in patients with congenital heart disease. Pediatr Cardiol 2009; 30: 363-366.
    • (2009) Pediatr Cardiol , vol.30 , pp. 363-366
    • Li, F.1    Xia, W.2    Yuan, S.3    Sun, R.4
  • 12
    • 69549129206 scopus 로고    scopus 로고
    • Evidence for rho-kinase activation in patients with pulmonary arterial hypertension
    • Doe Z, Fukumoto Y, Takaki A, Tawara S, Ohashi J, Nakano M, et al. Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension. Circ J 2009; 73: 1731-1739.
    • (2009) Circ J , vol.73 , pp. 1731-1739
    • Doe, Z.1    Fukumoto, Y.2    Takaki, A.3    Tawara, S.4    Ohashi, J.5    Nakano, M.6
  • 13
    • 79961067803 scopus 로고    scopus 로고
    • Rho-kinase: Important new therapeutic target in cardiovascular diseases
    • Satoh K, Fukumoto Y, Shimokawa H. Rho-kinase: Important new therapeutic target in cardiovascular diseases. Am J Physiol Heart Circ Physiol 2011; 301: H287-H296.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301 , pp. H287-H296
    • Satoh, K.1    Fukumoto, Y.2    Shimokawa, H.3
  • 14
    • 33646763902 scopus 로고    scopus 로고
    • Rho kinases in cardiovascular physiology and pathophysiology
    • Loirand G, Guerin P, Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ Res 2006; 98: 322-334.
    • (2006) Circ Res , vol.98 , pp. 322-334
    • Loirand, G.1    Guerin, P.2    Pacaud, P.3
  • 15
    • 84884603855 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled clinical trial with a rho-kinase inhibitor in pulmonary arterial hypertension
    • Fukumoto Y, Yamada N, Matsubara H, Mizoguchi M, Uchino K, Yao A, et al. Double-blind, placebo-controlled clinical trial with a rho-kinase inhibitor in pulmonary arterial hypertension. Circ J 2013; 77: 2619-2625.
    • (2013) Circ J , vol.77 , pp. 2619-2625
    • Fukumoto, Y.1    Yamada, N.2    Matsubara, H.3    Mizoguchi, M.4    Uchino, K.5    Yao, A.6
  • 16
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a rho-associated protein kinase in hypertension
    • Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997; 389: 990-994.
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1    Ishizaki, T.2    Satoh, H.3    Ono, T.4    Kawahara, T.5    Morishita, T.6
  • 17
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by g-proteins, rhokinase and protein phosphatase to smooth muscle and non-muscle myosin ii
    • Somlyo AP, Somlyo AV. Signal transduction by G-proteins, rhokinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol 2000; 522: 177-185.
    • (2000) J Physiol , vol.522 , pp. 177-185
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 19
    • 10744222390 scopus 로고    scopus 로고
    • Long-term treatment with a rho kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension
    • Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, et al. Long-term treatment with a Rho kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension. Circ Res 2004; 94: 385-393.
    • (2004) Circ Res , vol.94 , pp. 385-393
    • Abe, K.1    Shimokawa, H.2    Morikawa, K.3    Uwatoku, T.4    Oi, K.5    Matsumoto, Y.6
  • 20
    • 79960792540 scopus 로고    scopus 로고
    • Recent progress in the management of pulmonary hypertension
    • Fukumoto Y, Shimokawa H. Recent progress in the management of pulmonary hypertension. Circ J 2011; 75: 1801-1810.
    • (2011) Circ J , vol.75 , pp. 1801-1810
    • Fukumoto, Y.1    Shimokawa, H.2
  • 21
    • 84926261640 scopus 로고    scopus 로고
    • Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and eisenmenger syndrome: A clinical trial
    • Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, Behzadnia N, Sheybani-Afshar F, Fakhri M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger syndrome: A clinical trial. J Cardiol 2014; 64: 231-235.
    • (2014) J Cardiol , vol.64 , pp. 231-235
    • Sharif Kashani, B.1    Tahmaseb Pour, P.2    Malekmohammad, M.3    Behzadnia, N.4    Sheybani-Afshar, F.5    Fakhri, M.6
  • 22
    • 79952489220 scopus 로고    scopus 로고
    • Acute hemodynamic responses to adenosine and iloprost in patients with congenital heart defects and severe pulmonary arterial hypertension
    • Zhang DZ, Zhu XY, Meng J, Xue HM, Sheng XT, Han XM, et al. Acute hemodynamic responses to adenosine and iloprost in patients with congenital heart defects and severe pulmonary arterial hypertension. Int J Cardiol 2011; 147: 433-437.
    • (2011) Int J Cardiol , vol.147 , pp. 433-437
    • Zhang, D.Z.1    Zhu, X.Y.2    Meng, J.3    Xue, H.M.4    Sheng, X.T.5    Han, X.M.6
  • 23
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • Takemoto M, Sun J, Hiroki J, Shimokawa H, Liao JK. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation 2002; 106: 57-62.
    • (2002) Circulation , vol.106 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3    Shimokawa, H.4    Liao, J.K.5
  • 24
    • 42249112121 scopus 로고    scopus 로고
    • Assessment of operability of congenital cardiac shunts with increased pulmonary vascular resistance
    • Viswanathan S, Kumar RK. Assessment of operability of congenital cardiac shunts with increased pulmonary vascular resistance. Catheter Cardiovasc Interv 2008; 71: 665-670.
    • (2008) Catheter Cardiovasc Interv , vol.71 , pp. 665-670
    • Viswanathan, S.1    Kumar, R.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.