Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy

Journal of Experimental Medicine

Volumn 211, Issue 13, 2014, Pages 2617-2633

  Di Foggia, Valentina ^a   Zhang, Xinyu ^a   Licastro, Danilo ^b   Gerli, Mattia F M ^c   Phadke, Rahul ^d   Muntoni, Francesco ^d   Mourikis, Philippos ^e   Tajbakhsh, Shahragim ^e   Ellis, Matthew ^f   Greaves, Laura C ^g   Taylor, Robert W ^g   Cossu, Giulio ^h   Robson, Lesley G ^a   Marino, Silvia ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b CBM Scrl   (Italy)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^e CNRS   (France)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g NEWCASTLE UNIVERSITY   (United Kingdom)

^h UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; METALLOTHIONEIN I; TAMOXIFEN; BMI1 PROTEIN, MOUSE; METALLOTHIONEIN; METALLOTHIONEIN-1, MOUSE; ONCOPROTEIN; PAX7 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR PAX7;

ADULT; ADULT STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; DYSTROPHINOPATHY; ENZYME LINKED IMMUNOSORBENT ASSAY; GRIP STRENGTH TEST; HUMAN; IN VITRO STUDY; MOUSE; MUSCLE FUNCTION; MUSCLE REGENERATION; MUSCLE STRENGTH; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA EXTRACTION; SATELLITE CELL; SATELLITE CELL CULTURE; SKELETAL MUSCLE; TREADMILL TEST; UPREGULATION; WESTERN BLOTTING; ANIMAL; CHRONIC DISEASE; DISEASE MODEL; DNA DAMAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; INJURIES; MACULAR DEGENERATION; METABOLISM; MUSCLE DEVELOPMENT; PATHOLOGY; PATHOPHYSIOLOGY; REGENERATION; REPRODUCIBILITY; SKELETAL MUSCLE SATELLITE CELL; SYSTEMS BIOLOGY; TRANSGENIC MOUSE; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DNA DAMAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MACULAR DEGENERATION; METALLOTHIONEIN; MICE, INBRED MDX; MICE, TRANSGENIC; MUSCLE DEVELOPMENT; MUSCLE STRENGTH; MUSCLE, SKELETAL; OXIDATIVE STRESS; PAX7 TRANSCRIPTION FACTOR; POLYCOMB REPRESSIVE COMPLEX 1; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; REGENERATION; REPRODUCIBILITY OF RESULTS; SATELLITE CELLS, SKELETAL MUSCLE; SYSTEMS BIOLOGY;

EID: 84930054318     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20140317     Document Type: Article

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