Delphinidin induces cytotoxicity and potentiates cytocidal effect in combination with arsenite in an acute promyelocytic leukemia NB4 cell line

Oncology Reports

Volumn 34, Issue 1, 2015, Pages 43-50

  Yuan, Bo ^a   Okusumi, Saki ^a   Yoshino, Yuta ^a   Moriyama, Chihiro ^a   Tanaka, Sachiko ^a   Hirano, Toshihiko ^a   Takagi, Norio ^a   Toyoda, Hiroo ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Acute promyelocytic leukemia; Apoptosis; Arsenite; Cell cycle arrest; Delphinidin; NB4

Indexed keywords

ARSENITE SODIUM; CASPASE 3; CASPASE 8; CASPASE 9; DELPHINIDIN; PROTEIN BID; ANTHOCYANIN; ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; ARSENOUS ACID DERIVATIVE; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC50; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; DRUG POTENTIATION; GENE EXPRESSION REGULATION; LEUKEMIA, PROMYELOCYTIC, ACUTE; METABOLISM; TUMOR CELL LINE;

ANTHOCYANINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENITES; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE POTENTIAL, MITOCHONDRIAL;

EID: 84930022836     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3963     Document Type: Article

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