Selective serotonin reuptake inhibitor prescribing before, during and after pregnancy: A population-based study in six European regions

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 122, Issue 7, 2015, Pages 1010-1020

  Charlton, R A ^a   Jordan, S ^b   Pierini, A ^c   Garne, E ^d   Neville, A J ^e   Hansen, A V ^d   Gini, R ^f   Thayer, D ^b   Tingay, K ^b   Puccini, A ^g   Bos, H J ^h   Nybo Andersen, A M ⁱ   Sinclair, M ^j   Dolk, H ^j   De Jong Van Den Berg, L T W ^h  

^a University of Bath   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^d KOLDING HOSPITAL   (Denmark)

^e UNIVERSITY HOSPITAL OF FERRARA   (Italy)

^f Epidemiology Unit   (Italy)

^g Drug Policy Service   (Italy)

^h UNIVERSITY OF GRONINGEN   (Netherlands)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

^j UNIVERSITY OF ULSTER   (United Kingdom)

more..

Author keywords

Drug utilisation; electronic health records; pregnancy; serotonin uptake inhibitors

Indexed keywords

PAROXETINE; SEROTONIN UPTAKE INHIBITOR;

ADULT; ARTICLE; BIOGEOGRAPHIC REGION; COMPARATIVE STUDY; DENMARK; DEPRESSION; DESCRIPTIVE RESEARCH; DISEASE SEVERITY; DRUG USE; ELECTRONIC MEDICAL RECORD; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; ITALY; NETHERLANDS; PREGNANCY; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; STILLBIRTH; THIRD TRIMESTER PREGNANCY; UNITED KINGDOM; CLINICAL PRACTICE; DEPRESSIVE DISORDER; PREGNANCY COMPLICATIONS; STATISTICS AND NUMERICAL DATA;

ADULT; DENMARK; DEPRESSIVE DISORDER; FEMALE; GREAT BRITAIN; HUMANS; ITALY; NETHERLANDS; PHYSICIAN'S PRACTICE PATTERNS; PREGNANCY; PREGNANCY COMPLICATIONS; SEROTONIN UPTAKE INHIBITORS;

EID: 84930017541     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/1471-0528.13143     Document Type: Article

References (55)

1. King M, Nazareth I, Levy G, Walker C, Morris R, Weich S, et al., Prevalence of common mental disorders in general practice attendees across Europe. Br J Psychiatry 2008; 192: 362-7.
2. Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T,. Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol 2005; 106: 1071-83.
3. Bennett HA, Einarson A, Taddio A, Koren G, Einarson TR,. Prevalence of depression during pregnancy: systematic review. Obstet Gynecol 2004; 103: 698-709.
4. Gruppo di lavoro OsMed. Rapporto nazionale anno 2007 [OsMedWorking Team. The Drug Utilisation in Italy. National Reports 2007]. Rome: Il Pensiero Scientifico Editore; 2008 [ www.agenziafarmaco.gov.it/sites/default/files/rapporto-osmed-2007-0.pdf ]. Accessed 23 July 2014.
5. Reefhuis J, Rasmussen SA, Friedman JM,. Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn. N Engl J Med 2006; 354: 2188-90.
6. Cooper WO, Willy ME, Pont SJ, Ray WA,. Increasing use of antidepressants in pregnancy. Am J Obstet Gynecol 2007; 196: 544.e541-5.
7. Alwan S, Reefhuis J, Rasmussen SA, Friedman JM, National Birth Defects Prevention Service. Patterns of antidepressant medication use among pregnant women in a United States population. J Clin Pharmacol 2011; 51: 264-70.
8. Bakker MK, Kölling P, Van Den Berg PB, De Walle HEK, De Jong van den Berg LTW,. Increase in use of selective serotonin reuptake inhibitors in pregnancy during the last decade, a population-based cohort study from the Netherlands. J Clin Pharmacol 2008; 65: 600-6.
9. Colvin L, Slack-Smith L, Stanley FJ, Bower C,. Dispensing patterns and pregnancy outcomes for women dispensed selective serotonin reuptake inhibitors in pregnancy. Birth Defects Res A Clin Mol Teratol 2011; 91: 142-52.
10. Lattimore KA, Donn SM, Kaciroti N, Kemper AR, Neal CR, Vazquez DM,. Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: a meta-analysis. J Perinatol 2005; 25: 595-604.
11. Nikfar S, Rahimi R, Hendoiee N, Abdollahi M,. Increasing the risk of spontaneous abortion and major malformations in newborns following use of serotonin reuptake inhibitors during pregnancy: a systematic review and updated meta-analysis. Daru 2012; 20: 75.
12. Bakker MK, Kerstjens-Frederikse WS, Buys CH, de Walle HE, de Jong-van den Berg LT,. First-trimester use of paroxetine and congenital heart defects: a population-based case-control study. Birth Defects Res A Clin Mol Teratol 2010; 88: 94-100.
13. Chambers CD, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, et al., Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med 2006; 354: 579-87.
14. Kieler H, Artama M, Engeland A, Ericsson Ö, Furu K, Gissler M, et al., Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries. BMJ 2012; 344: d8012.
15. Gentile S,. The safety of newer antidepressants in pregnancy and breastfeeding. Drug Saf 2005; 28: 137-52.
16. Toh S, Mitchell AA, Louik C, Werler MM, Chambers CD, Hernandez-Diaz S,. Selective serotonin reuptake inhibitor use and risk of gestational hypertension. Am J Psychiatry 2009; 166: 320-8.
17. Cohen L, Altshuler L, Harlow B, Nonacs R, Newport D, Viguera A, et al., Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment. J Am Med Assoc 2006; 295: 499-507.
18. Singh S, Sedgh G, Hussain R,. Unintended pregnancy: worldwide levels, trends, and outcomes. Stud Fam Plann 2010; 41: 241-50.
19. EUROmediCAT. Safety of Medication Use in Pregnancy. 2011 [ http://euromedicat.eu/ ]. Accessed 31 July 2014.
20. Dolk H,. EUROCAT: 25 years of European surveillance of congenital anomalies. Arch Dis Child Fetal Neonatal Ed 2005; 90: F355-8.
21. Coloma PM, Trifirò G, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, et al., Electronic healthcare databases for active drug safety surveillance: is there enough leverage? Pharmacoepidemiol Drug Saf 2012; 21: 611-21.
22. Gagne JJ, Maio V, Berghella V, Louis DZ, Gonnella JS,. Prescription drug use during pregnancy: a population-based study in Regione Emilia-Romagna, Italy. Eur J Clin Pharmacol 2008; 64: 1125-32.
23. Ford D, Jones K, Verplancke J-P, Lyons R, John G, Brown G, et al., The SAIL Databank: building a national architecture for e-health research and evaluation. BMC Health Serv Res 2009; 9: 157.
24. Lyons R, Jones K, John G, Brooks C, Verplancke J-P, Ford D, et al., The SAIL databank: linking multiple health and social care datasets. BMC Med Inform Decis Mak 2009; 9: 3.
25. Wood L, Martinez C,. The General Practice Research Database: role in pharmacovigilance. Drug Saf 2004; 27: 871-81.
26. Thygesen LC, Daasnes C, Thaulow I, Brønnum-Hansen H,. Introduction to Danish (nationwide) registers on health and social issues: structure, access, legislation, and archiving. Scand J Public Health 2011; 39 (7 Suppl): 12-16.
27. Lynge E, Sandegaard JL, Rebolj M,. The Danish National Patient Register. Scand J Public Health 2011; 39 (7 Suppl): 30-3.
28. Wallach Kildemoes H, Toft Sørensen H, Hallas J,. The Danish National Prescription Registry. Scand J Public Health 2011; 39 (7 Suppl): 38-41.
29. Visser ST, Schuiling-Veninga CCM, Bos JHJ, de Jong-van den Berg LTW, Postma MJ,. The population-based prescription database IADB.nl: its development, usefulness in outcomes research and challenges. Expert Rev Pharmacoecon Outcomes Res 2013; 13: 285-92.
30. Charlton RA, Neville AJ, Jordan S, Pierini A, Damase-Michel C, Klungsøyr K, et al., Healthcare databases in Europe for studying medicine use and safety during pregnancy. Pharmacoepidemiol Drug Saf 2014; 23: 586-94.
31. van Gelder MHJ, Rooij ILM, Walle HK, Roeleveld N, Bakker M,. Maternal recall of prescription medication use during pregnancy using a paper-based questionnaire. Drug Saf 2013; 36: 43-54.
32. Jordan S, Watkins A, Storey M, Allen SJ, Brooks CJ, Garaiova I, et al., Volunteer bias in recruitment, retention, and blood sample donation in a randomised controlled trial involving mothers and their children at six months and two years: a longitudinal analysis. PLoS One 2013; 8: e67912.
33. van Geffen ECG, Gardarsdottir H, van Hulten R, van Dijk L, Egberts ACG, Heerdink ER,. Initiation of antidepressant therapy: do patients follow the GP's prescription? Br J Gen Pract 2009; 59: 81-7.
34. Beardon PH, McGilchrist MM, McKendrick AD, McDevitt DG, MacDonald TM,. Primary non-compliance with prescribed medication in primary care. BMJ 1993; 307: 846-8.
35. Fischer MA, Stedman MR, Lii J, Vogeli C, Shrank WH, Brookhart A, et al., Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med 2010; 25: 284-90.
36. National Institute for Health and Clinical Excellence. Antenatal and postnatal mental health. Clinical management and service guidance. 2007 [ www.nice.org.uk/guidance/cg45/resources/guidance-antenatal-and-postnatal-mental-health-pdf ]. Accessed 18 August 2014.
37. Petersen I, Gilbert RE, Evans SJ, Man SL, Nazareth I,. Pregnancy as a major determinant for discontinuation of antidepressants: an analysis of data from The Health Improvement Network. J Clin Psychiatry 2011; 72: 979-85.
38. Ververs T, Kaasenbrood H, Visser G, Schobben F, Jong-van den Berg L, Egberts T,. Prevalence and patterns of antidepressant drug use during pregnancy. Eur J Clin Pharmacol 2006; 62: 863-70.
39. Engelbrecht AST,. Forbruget af Antidepressiva 2001-2011. Dataleverancer og Lægemiddelstatistik Sektor for National Sundhedsdokumentation og Forskning. Copenhagen: Statens Serum Institute, 2012. 21 May 2013.
40. Andrade SE, Raebel MA, Brown J, Lane K, Livingston J, Boudreau D, et al., Use of antidepressant medications during pregnancy: a multisite study. Am J Obstet Gynecol 2008; 198: 194.e191-5.
41. Huybrechts KF, Palmsten K, Mogun H, Kowal M, Avorn J, Setoguchi-Iwata S, et al., National trends in antidepressant medication treatment among publicly insured pregnant women. Gen Hosp Psychiatry 2013; 35: 265-71.
42. Ramos É, Oraichi D, Rey É, Blais L, Bérard A,. Prevalence and predictors of antidepressant use in a cohort of pregnant women. BJOG 2007; 114: 1055-64.
43. Heaney P,. Antidepressant prescriptions up amid therapy delays. 2012 [ www.bbc.co.uk/news/uk-wales-19289669 ]. Accessed 12 November 2013.
44. Office for National Statistics. Regional Gross Disposable Household Income (GDHI) 2011. 2013 [ www.ons.gov.uk/ons/dcp171778-307651.pdf ]. Accessed 1 October 2013.
45. Damiani G, Federico B, Silvestrini G, Bianchi C, Anselmi A, Iodice L, et al., Impact of regional copayment policy on selective serotonin reuptake inhibitor (SSRI) consumption and expenditure in Italy. Eur J Clin Pharmacol 2013; 69: 957-63.
46. Wurst KE, Poole C, Ephross SA, Olshan AF,. First trimester paroxetine use and the prevalence of congenital, specifically cardiac, defects: a meta-analysis of epidemiological studies. Birth Defects Res A Clin Mol Teratol 2010; 88: 159-70.
47. Nederlandse Vereniging voor obstetrie en gynaecologie (NVOG)., Richtlijn,. SSRI-gebruik in de zwangerschap en tijdens lactatie. 2012 [ www.nvog-documenten.nl ]. Accessed 5 May 2013.
48. Agenzia Italiana del Farmaco AIFA. Nota informativa importante concordata con le autorità regolatorie Europee e l'Agenzia Italiana del Farmaco (AIFA). 2006 [ www.agenziafarmaco.gov.it/sites/default/files/111.86876.11401890146983587.pdf ]. Accessed 30 September 2013.
49. Agenzia Italiana del Farmaco AIFA. Raccomandazioni del Working Group Pediatrico dell'AIFA in relazione all'eposizione in utero di antidepressivi. 2010 [ www.agenziafarmaco.gov.it/sites/default/files/paroxetina-raccomandazione-wgp-23112010.pdf ]. Accessed 30 September 2013.
50. Videbech P, Christensen KS, Hansen PEB,. Antidepressiv behandling af gravide 2013. [ http://pro.medicin.dk/Sygdomme/Sygdom/318339 ]. Accessed 25 August 2014.
51. Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, Shelton RC, et al., Antidepressant drug effects and depression severity: a patient-level meta-analysis. J Am Med Assoc 2010; 303: 47-53.
52. McAndrew F, Thompson J, Fellows L, Large A, Speed M, Renfrew M,. The Infant Feeding Survey 2010. NHS Information Centre for Health and Social Care, Office of National Statistics. 2012 [ http://data.gov.uk/dataset/infant-feeding-survey-2010 ]. Accessed 22 June 2013.
53. Lauria L, Spinelli A, Lamberti A, Buoncritiano M, Bucciarelli M, Andreozzi S, et al., Breastfeeding: prevalences, duration and associated factors from two Italian surveys-2008 and 2011. Not Ist Super Sanità 2012;25:i-iii. [ www.epicentro.iss.it/ben/2012/november/2011.asp ]. Accessed 30 January 2014.
54. Busck-Rasmussen M, Fredsted Villadsen S, Nyboe Norsker F, Mortensen L, Nybo Andersen A,. Breastfeeding practices in relation to country of origin among women living in Denmark: a popu-lation-based study. Matern Child Health J 2014; 18: 2479-2488.
55. UK National Screening Committee. Postnatal depression screening policy position statement. 2011 [ www.screening.nhs.uk/policydb-download.php?doc=189 ]. Accessed 1 October 2013.