Initiation of antidepressant therapy: Do patients follow the GP's prescription?

British Journal of General Practice

Volumn 59, Issue 559, 2009, Pages 81-88

  van Geffen, Erica C G ^a   Gardarsdottir, Helga ^a   van Hulten, Rolf ^a   van Dijk, Liset ^b   Egberts, Antoine C G ^a,c   Heerdink, Eibert R ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS INSTITUTE FOR HEALTH SERVICES RESEARCH   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Antidepressants; Anxiety; Depression; Patient nonadherence; Treatment refusal

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; ANXIETY DISORDER; ARTICLE; CONSULTATION; CONTROLLED STUDY; DEPRESSION; FEMALE; GENERAL PRACTITIONER; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSESSIVE COMPULSIVE DISORDER; PANIC; PATIENT ATTITUDE; PATIENT COMPLIANCE; PRESCRIPTION; RETROSPECTIVE STUDY; TREATMENT INDICATION;

ADOLESCENT; ADULT; AGED; ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER; DRUG PRESCRIPTIONS; EPIDEMIOLOGIC METHODS; FAMILY PRACTICE; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NETHERLANDS; PATIENT COMPLIANCE; RISK FACTORS; YOUNG ADULT;

EID: 59849125708     PISSN: 09601643     EISSN: None     Source Type: Journal    
DOI: 10.3399/bjgp09X395067     Document Type: Article

References (38)

1. Donovan JL, Blake DR. Patient non-compliance: deviance or reasoned decision-making? Soc Sci Med 1992; 34(5): 507-513.
2. Home R, Weinman J. Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 1999; 47(6): 555-567.
3. Bull SA, Hunkeler EM, Lee JY, et al. Discontinuation or switching selective serotonin-reuptake inhibitors. Ann Pharmacother 2002; 36(4): 578-584.
4. Lin EHB, Von Korff M, Katon W, et al. The role of the primary care physician in patients' adherence to antidepressant therapy. Med Care 1995; 33(1): 67-74.
5. Demytteuaere K, Enzlin P, Dewé W, et al. Compliance with antidepressants in a primary care setting, 1: beyond lack of efficacy and adverse events. J Clin Psychiatry 2001; 62(suppl 22): 30-33.
6. Meijer WEE, Heerdink ER, Lenflrens HMG, et al. Incidence and determinants of long-term use of antidepressants. Eur J Clin Pharmacol 2004; 60(1): 57-61.
7. Maddox JC, Levi M, Thompson C. The compliance with antidepressants in general practice, J Psychopharmacol 1994; 8(suppl 1): 48-53.
8. Olfson M, Marcus SC, Tedeschi M, Wan GJ. Continuity of antidepressant treatment for adults with depression in the United States. Am J Psychiatry 2006; 163(1): 101-108.
9. Demyttenaere K, Enzlin P, Dewé W, et al. Compliance with antidepressants in a primary care setting, 2: the influence of gender and type of impairment. J Clin Psychiatry 2001; 62(supp122): 34-37.
10. Cohen N, Parikh SV, Kennedy SH. Medication compliance in mood disorders: relevance of the Health Belief Model and other deterrnmants. Prim Care Psychiatry 2000; 6: 101-110.
11. Lingam R, Scott J. Treatment non-adherence in affective disorders. Acta Psychiatr Scand 2002; 105: 164-172.
12. Van Dijk L, Heerdink ER, Somai D, et al. Patient risk profiles and practice variation in nouadherence to antidepressants, andhypertensives and oral hypoglycemics. BMC Health Serv Res 2007; 7: 51.
13. Sirey JO, Bruce ML, Alexopoulos GS, et al. Stigma as a barrier to recovery: Perceived stigma and patient-rated severity of illness as predictors of antidepressant drug adherence. Psychiatr Serv 2001; 52(12): 1615-1620.
14. Waters WHR, Gould NV, Lunn JE. Undispensed prescriptions in a mining general practice. BMJ 1976; 1(6071): 1062-1063.
15. Rashid A. Do patients cash prescriptions? BMJ 1982; 284(6308): 24-26.
16. Beardon PHG, McGilchrist MM, McKendrick AD, et al. Primary non-compliance with prescribed medication in primary care. BMJ 1993; 307(6908): 846-848.
17. McGettigan P, Kelly A, Carvahlo M, Feely J. Antidepressants in primary care: analysis of treatment discontinuations. Pharmacoepidemiol Drug Saf 2000; 9: 521-528.
18. Hansen GH, Vach W, Roshohn J-U, et al. Early discontinuation of antidepressants in general practice: association with patient and prescriber characteristics. Fam Pract 2004; 21(6): 623-629.
19. Simon GE, VonKorff M, Wagner EH, Barlow W. Patterns of antidepressant use in community practice. Gen Hosp Psychiatry 1993; 15(6): 399-405.
20. Van Geffen ECG, van Huhen R, Bouvy ML, et al. Characteristics and reasons associated with nonacceptance of selective serotonin-reuptake inhibitor treatment. Ann Pharmacother 2008; 42(2): 218-225.
21. Westert GP, Schellevis FG, de Bakker DH, et al. Monitoring health inequalities through general practice: the Second Dutch Survey of General Practice. Eur J Public Health 2005; 15(1): 59--65.
22. Lamberts H, Wood M. International classification of primary care. Oxford: Oxford University Press, 1987.
23. Florentinus SR, Souverein PC, Griens AMGF, et al. Linking community pharmacy dispensing data to prescribing data of general practitioners. BMC Health Serv Res 2006; 6: 18.
24. Bull SA, Hu XH, Hunkeler EM, et al. Discontinuation of use and switching of antidepressants: influence of patient-physician communication. JAMA 2002; 288(11): 1403-1409.
25. Gardarsdottir H, Heerdink ER, van Dijk L, Egberts ACG. Indications for antidepressant drug prescribing in general practice in the Netherlands. J Affect Disord 2007; 98(1-2): 109-115.
26. Pomerantz JM, Finkelstein SN, Bemdt ER, et al. Prescriber intent, off-label usage, and early discontinuation of antidepressants: a retrospective physician survey and data analysis. J Clin Psychiatry 2004; 65(3): 395-404.
27. Hyde J, Calnan M, Prior L, et al. A qualitative study exploring how GPs decide to prescribe antidepressants. Br J Gen Pract 2005; 55(519): 755-762.
28. Kendrick T, King F, Albertella L, Smith PWF. GP treatment decisions for patients with depression: an observational study. Br J Gen Pract 2005; 55(513): 280-286.
29. Anonymous. Mild depression in primary care: time for a rethink? Drug Ther Bull 2003; 41(10): 60-64.
30. Chew-Graham CA, May CR, Cole H, Hedley S. The burden of depression in primary care: a qualitative investigation of general practitioners' constructs of depressed people in the inner city. Prim Care Psychiatry 2000; 6: 137-141.
31. Klinkman MS, Coyne JC, Gallo S, Schwenk TL. False positive, false negative, and the validity of the diagnosis of major depression in primary care. Arch Fam Med 1998; 7(5): 451-461.
32. Britten N. Patient demands for prescriptions: a view from the other side. Fam Pract 1994; 11(1): 62-66.
33. Lowe B, Schultz U, Grafe K, Wilke S. Medical patients' attitudes toward emotional problems and their treatment. What do they really want? J Gen Intern Med 2006; 21(1): 39-45.
34. Van Schaik DJF, Klijn AFJ, van Hout HPJ, et al. Patients' preferences in the treatment of depressive disorder in primary care. Gen Hosp Psychiatry 2004; 26(3): 184-189.
35. Wakers K, Buszewicz M, Weich S, King M. Help-seeking preferences for psychological distress in primary care: effect of current mental state. Br J Gen Pract 2008; 58: 694-698.
36. Backenstrass M, Joest K, Rosemann T, Szecsenyi J. The care of patients with subtreshold depression in primary care: is it all that bad? A qualitative study on the views of general practitioners and patients. BMC Health Serv Res 2007; 7: 190.
37. Hansen HV, Kessing LV Adherence to antidepressant treatment. Expert Rev Neurother 2007; 7(1): 57-62.
38. Uiters E, van Dijk L, Deville WD, et al. Ethnic minorities and prescription medication; concordance between selfreports and medical records. BMC Health Serv Res 2006; 6: 115.