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Volumn 9, Issue 6, 2015, Pages 2743-2749

miR-218 inhibits the proliferation of glioma U87 cells through the inactivation of the CDK6/cyclin D1/p21Cip1/Waf1 pathway

Author keywords

CDK6; Cyclin D1; Gliomas; miR 218; P21Cip1 Waf1; Proliferation

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 6; MICRORNA; MICRORNA 218; PROTEIN P21; UNCLASSIFIED DRUG;

EID: 84930000387     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2015.3068     Document Type: Article
Times cited : (22)

References (28)
  • 1
    • 84865596273 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits human brain glioma cell growth by down-regulation of Notch1
    • Yu X, Zhang W, Ning Q and Luo X: MicroRNA-34a inhibits human brain glioma cell growth by down-regulation of Notch1. J Huazhong Univ Sci Technolog Med Sci 32: 370-374, 2012.
    • (2012) J Huazhong Univ Sci Technolog Med Sci , vol.32 , pp. 370-374
    • Yu, X.1    Zhang, W.2    Ning, Q.3    Luo, X.4
  • 4
    • 84867512779 scopus 로고    scopus 로고
    • p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50
    • Wang R, Jiao Z, Li R, et al: p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50. Neuro Oncol 14: 1116-1124, 2012.
    • (2012) Neuro Oncol , vol.14 , pp. 1116-1124
    • Wang, R.1    Jiao, Z.2    Li, R.3
  • 5
    • 84863499867 scopus 로고    scopus 로고
    • Lentiviral expression of anti-microRNAs tar geting miR-27a inhibits proliferation and invasiveness of U87 gliomacells
    • Feng SY, Dong CG, Wu WK, et al: Lentiviral expression of anti-microRNAs tar geting miR-27a inhibits proliferation and invasiveness of U87 gliomacells. Mol Med Rep 6: 275-281, 2012.
    • (2012) Mol Med Rep , vol.6 , pp. 275-281
    • Feng, S.Y.1    Dong, C.G.2    Wu, W.K.3
  • 6
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM and Kosik KS: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033, 2005.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP: MicroRNAs: Target recognition and regulatory functions. Cell 136: 215-233, 2009.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 84860386287 scopus 로고    scopus 로고
    • Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders
    • Long JM and Lahiri DK: Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders. Exp Neurol 235: 402-418, 2012.
    • (2012) Exp Neurol , vol.235 , pp. 402-418
    • Long, J.M.1    Lahiri, D.K.2
  • 9
    • 17844382749 scopus 로고    scopus 로고
    • ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner
    • Park S and James CD: ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner. Oncogene 24: 2495-2502, 2005.
    • (2005) Oncogene , vol.24 , pp. 2495-2502
    • Park, S.1    James, C.D.2
  • 10
    • 84859487640 scopus 로고    scopus 로고
    • MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction
    • Xu B, Hsu PK, Karayiorgou M and Gogos JA: MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction. Neurobiol Dis 46: 291-301, 2012.
    • (2012) Neurobiol Dis , vol.46 , pp. 291-301
    • Xu, B.1    Hsu, P.K.2    Karayiorgou, M.3    Gogos, J.A.4
  • 13
    • 77957561251 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma
    • Rao SAM, Santosh V and Somasundaram K: Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma. Mod Pathol 23: 1404-1417, 2010.
    • (2010) Mod Pathol , vol.23 , pp. 1404-1417
    • Rao, S.A.M.1    Santosh, V.2    Somasundaram, K.3
  • 15
    • 84875716955 scopus 로고    scopus 로고
    • MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity
    • Xia H, Yan Y, Hu M, et al: MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity. Neuro Oncol 15: 413-422, 2013.
    • (2013) Neuro Oncol , vol.15 , pp. 413-422
    • Xia, H.1    Yan, Y.2    Hu, M.3
  • 16
    • 84865320856 scopus 로고    scopus 로고
    • MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1
    • Liu Y, Yan W, Zhang W, et al: MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. Oncol Rep 28: 1013-1021, 2012.
    • (2012) Oncol Rep , vol.28 , pp. 1013-1021
    • Liu, Y.1    Yan, W.2    Zhang, W.3
  • 17
    • 80051746246 scopus 로고    scopus 로고
    • Relationship between miR-218 and CDK6 expression and their biological impact on glioma cell proliferation and apoptosis
    • (In Chinese)
    • Zhang JM, Sun CY, Yu SZ, et al: Relationship between miR-218 and CDK6 expression and their biological impact on glioma cell proliferation and apoptosis. Zhonghua Bing Li Xue Za Zhi 40: 454-459, 2011 (In Chinese).
    • (2011) Zhonghua Bing Li Xue Za Zhi , vol.40 , pp. 454-459
    • Zhang, J.M.1    Sun, C.Y.2    Yu, S.Z.3
  • 18
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis DN, Ohgaki H, Wiestler OD, et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114: 97-109, 2007.
    • (2007) Acta Neuropathol , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 19
    • 84872530278 scopus 로고    scopus 로고
    • miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation
    • Cai J, Wu J, Zhang H, Fang L, Huang Y, Yang Y, Zhu X, Li R and Li M: miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation. Cancer Res 73: 756-766, 2013.
    • (2013) Cancer Res , vol.73 , pp. 756-766
    • Cai, J.1    Wu, J.2    Zhang, H.3    Fang, L.4    Huang, Y.5    Yang, Y.6    Zhu, X.7    Li, R.8    Li, M.9
  • 20
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • Molinari M: Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif 33: 261-274, 2000.
    • (2000) Cell Prolif , vol.33 , pp. 261-274
    • Molinari, M.1
  • 21
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ and Roberts JM: CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev 13: 1501-1512, 1999.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 22
    • 84875807408 scopus 로고    scopus 로고
    • Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer
    • Wu Z, He B, He J and Mao X: Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer. Prostate 73: 596-604, 2013.
    • (2013) Prostate , vol.73 , pp. 596-604
    • Wu, Z.1    He, B.2    He, J.3    Mao, X.4
  • 23
    • 33749528151 scopus 로고    scopus 로고
    • miRNAs and apoptosis: RNAs to die for
    • Jovanovic M and Hengartner MO: miRNAs and apoptosis: RNAs to die for. Oncogene 25: 6176-6187, 2006.
    • (2006) Oncogene , vol.25 , pp. 6176-6187
    • Jovanovic, M.1    Hengartner, M.O.2
  • 24
    • 84880181637 scopus 로고    scopus 로고
    • MiRNA-329 targeting E2F1 inhibits cell proliferation in glioma cells
    • Xiao B, Tan L, He B, et al: MiRNA-329 targeting E2F1 inhibits cell proliferation in glioma cells. J Transl Med 11: 172, 2013.
    • (2013) J Transl Med , vol.11 , pp. 172
    • Xiao, B.1    Tan, L.2    He, B.3
  • 25
    • 33749507943 scopus 로고    scopus 로고
    • A small piece in the cancer puzzle: MicroRNAs as tumor suppressors and oncogenes
    • Kent OA and Mendell JT: A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene 25: 6188-6196, 2006.
    • (2006) Oncogene , vol.25 , pp. 6188-6196
    • Kent, O.A.1    Mendell, J.T.2
  • 26
    • 42249105032 scopus 로고    scopus 로고
    • Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells
    • Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP and Khan SA: Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells. Oncogene 27: 2575-2582, 2008.
    • (2008) Oncogene , vol.27 , pp. 2575-2582
    • Martinez, I.1    Gardiner, A.S.2    Board, K.F.3    Monzon, F.A.4    Edwards, R.P.5    Khan, S.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.