Preoperative oral carbohydrate therapy

Current Opinion in Anaesthesiology

Volumn 28, Issue 3, 2015, Pages 364-369

  Nygren, Jonas ^a,b   Thorell, Anders ^a,b   Ljungqvist, Olle ^c  

^a DANDERYD HOSPITAL   (Sweden)

^b ERSTA HOSPITAL   (Sweden)

^c Örebro University   (Sweden)

Author keywords

insulin resistance; preoperative fasting; preoperative oral carbohydrates

Indexed keywords

CARBOHYDRATE; INSULIN;

ABDOMINAL SURGERY; COHORT ANALYSIS; CONVALESCENCE; DIET RESTRICTION; HOSPITALIZATION; HUMAN; IMMUNE RESPONSE; INJURY; INSULIN RESISTANCE; MAJOR SURGERY; METABOLISM; MUSCLE FUNCTION; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; PREOPERATIVE CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SURGICAL STRESS; WELLBEING; ORAL DRUG ADMINISTRATION; POSTOPERATIVE PERIOD; PROCEDURES;

ADMINISTRATION, ORAL; CARBOHYDRATES; FASTING; HUMANS; INSULIN RESISTANCE; POSTOPERATIVE PERIOD; PREOPERATIVE CARE;

EID: 84929996094     PISSN: 09527907     EISSN: 14736500     Source Type: Journal    
DOI: 10.1097/ACO.0000000000000192     Document Type: Review

References (45)

1. Nygren J. The metabolic effects of fasting and surgery. Best Pract Res Clin Anaesthesiol 2006; 20:429-438.
2. Brandi LS, Frediani M, Oleggini M, et al. Insulin resistance after surgery: normalization by insulin treatment. Clin Sci (Colch) 1990; 79:443-450.
3. Thorell A, Nygren J, Ljungqvist O. Insulin resistance: a marker of surgical stress. Curr Opin Clin Nutr Metab Care 1999; 2:69-78.
4. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345:1359-1367.
5. Ljungqvist O, Nygren J, Thorell A. Modulation of postoperative insulin resistance by preoperative carbohydrate loading. Proc Nutr Soc 2002; 61:329-336.
6. Nygren J, Thorell A, Brismar K, et al. Short-term hypocaloric nutrition but not bed rest decrease insulin sensitivity and IGF-I bioavailability in healthy subjects: the importance of glucagon. Nutrition 1997; 13:945-951.
7. Brady M, Kinn S, Stuart P. Preoperative fasting for adults to prevent perioperative complications. Cochrane Database Syst Rev 2003; (4):CD004423.
8. Ljungqvist O. Modulating postoperative insulin resistance by preoperative carbohydrate loading. Best Pract Res Clin Anaesthesiol 2009; 23:401-409.
9. Ljungqvist O, Thorell A, Gutniak M, et al. Glucose infusion instead of preoperative fasting reduces postoperative insulin resistance. J Am Coll Surg 1994; 178:329-336.
10. Crowe PJ, Dennison A, Royle GT. The effect of preoperative glucose loading on postoperative nitrogen metabolism. Br J Surg 1984; 71:635-637.
11. Nygren JO, Thorell A, Soop M, et al. Perioperative insulin and glucose infusion maintains normal insulin sensitivity after surgery. Am J Physiol 1998; 275 (1 Pt 1):E140-E148.
12. Nygren J, Thorell A, Jacobsson H, et al. Preoperative gastric emptying. Effects of anxiety and oral carbohydrate administration. Ann Surg 1995; 222:728-734.
13. Soop M, Nygren J, Myrenfors P, et al. Preoperative oral carbohydrate treatment attenuates immediate postoperative insulin resistance. Am J Physiol Endocrinol Metab 2001; 280:E576-E583.
14. Ljunggren S, Hahn RG, Nystrom T. Insulin sensitivity and beta-cell function after carbohydrate oral loading in hip replacement surgery: a double-blind, randomised controlled clinical trial. Clin Nutr 2014; 33:392-398.
15. Soop M, Nygren J, Thorell A, et al. Preoperative oral carbohydrate treatment attenuates endogenous glucose release 3 days after surgery. Clin Nutr 2004; 23:733-741.
16. Svanfeldt M, Thorell A, Hausel J, et al. Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics. Br J Surg 2007; 94:1342-1350.
17. Melis GC, van Leeuwen PA, von Blomberg-van der Flier BM, et al. A carbohydrate-rich beverage prior to surgery prevents surgery-induced immunodepression: a randomized, controlled, clinical trial. JPEN J Parenter Enteral Nutr 2006; 30:21-26.
18. Svanfeldt M, Thorell A, Hausel J, et al. Effect of 'preoperative' oral carbohydrate treatment on insulin action: a randomised cross-over unblinded study in healthy subjects. Clin Nutr 2005; 24:815-821.
19. Gjessing PF, Hagve M, Fuskevag OM, et al. Single-dose carbohydrate treatment in the immediate preoperative phase diminishes development of postoperative peripheral insulin resistance. Clin Nutr 2015; 34:156-164. This important experimental study in pigs obtained similar to what has been achieved in previous clinical studies in surgical patients. This experimental setting will provide an opportunity to further elucidate mechanisms behind the benefits of POC on postoperative metabolism.
20. Witasp A, Nordfors L, Schalling M, et al. Increased expression of inflammatory pathway genes in skeletal muscle during surgery. Clin Nutr 2009; 28:291-298.
21. Witasp A, Nordfors L, Schalling M, et al. Expression of inflammatory and insulin signaling genes in adipose tissue in response to elective surgery. J Clin Endocrinol Metab 2010; 95:3460-3469.
22. Thorell A, Loftenius A, Andersson B, Ljungqvist O. Postoperative insulin resistance and circulating concentrations of stress hormones and cytokines. Clin Nutr 1996; 15:75-79.
23. Thorell A, Hirshman MF, Nygren J, et al. Exercise and insulin cause GLUT-4 translocation in human skeletal muscle. Am J Physiol 1999; 277 (4 Pt 1): E733-E741.
24. Vigano J, Cereda E, Caccialanza R, et al. Effects of preoperative oral carbohydrate supplementation on postoperative metabolic stress response of patients undergoing elective abdominal surgery. World J Surg 2012; 36:1738-1743.
25. Perrone F, da-Silva-Filho AC, Adorno IF, et al. Effects of preoperative feeding with a whey protein plus carbohydrate drink on the acute phase response and insulin resistance. A randomized trial. Nutr J 2011; 10:66.
26. Pexe-Machado PA, de Oliveira BD, Dock-Nascimento DB, de Aguilar-Nascimento JE. Shrinking preoperative fast time with maltodextrin and protein hydrolysate in gastrointestinal resections due to cancer. Nutrition 2013; 29:1054-1059.
27. Gjessing PF, Constantin-Teodosiu D, Hagve M, et al. Preoperative carbohydrate supplementation attenuates postsurgery insulin resistance via reduced inflammatory inhibition of the insulin-mediated restraint on muscle pyruvate dehydrogenase kinase 4 expression. Clin Nutr 2014. [Epub ahead of print]. doi: 10.1016/j.clnu.2014.12.004.
28. Awad S, Constantin-Teodosiu D, Constantin D, et al. Cellular mechanisms underlying the protective effects of preoperative feeding: a randomized study investigating muscle and liver glycogen content, mitochondrial function, gene and protein expression. Ann Surg 2010; 252:247-253.
29. Yu Y, Zhou YB, Liu HC, et al. Effects of preoperative oral carbohydrate on postoperative insulin resistance in radical gastrectomy patients. Zhonghua Wai Ke Za Zhi 2013; 51:696-700.
30. Smith MD, McCall J, Plank L, et al. Preoperative carbohydrate treatment for enhancing recovery after elective surgery. Cochrane Database Syst Rev 2014; 8:CD009161.
31. Luttikhold J, Oosting A, van den Braak CC, et al. Preservation of the gut by preoperative carbohydrate loading improves postoperative food intake. Clin Nutr 2013; 32:556-561.
32. Hausel J, Nygren J, Thorell A, et al. Randomized clinical trial of the effects of oral preoperative carbohydrates on postoperative nausea and vomiting after laparoscopic cholecystectomy. Br J Surg 2005; 92:415-421.
33. Sada F, Krasniqi A, Hamza A, et al. A randomized trial of preoperative oral carbohydrates in abdominal surgery. BMC Anesthesiol 2014; 14:93.
34. Singh BN, Dahiya D, Bagaria D, et al. Effects of preoperative carbohydrates drinks on immediate postoperative outcome after day care laparoscopic cholecystectomy. Surg Endosc 2015. [Epub ahead of print]
35. Fearon KC, Ljungqvist O, Von Meyenfeldt M, et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 2005; 24:466-477.
36. Kehlet H. Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 1997; 78:606-617.
37. Soop M, Carlson GL, Hopkinson J, et al. Randomized clinical trial of the effects of immediate enteral nutrition on metabolic responses to major colorectal surgery in an enhanced recovery protocol. Br J Surg 2004; 91:1138-1145.
38. Gustafsson UO, Hausel J, Thorell A, et al. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 2011; 146:571-577.
39. ERAS Compliance Group. The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an international registry. Ann Surg 2015. [Epub ahead of print]
40. Roulin D, Donadini A, Gander S, et al. Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 2013; 100:1108-1114.
41. Vlug MS, Wind J, Hollmann MW, et al. Laparoscopic in combination with fast track surgery is the best preoperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study). Ann Surg 2011; 254:868-875.
42. Perioperative total parenteral nutrition in surgical patients. The Veterans Affairs Total Parenteral Nutrition Cooperative Study Group. N Engl J Med 1991; 325:525-532.
43. Gustafsson UO, Scott MJ, Schwenk W, et al. Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS1) Society recommendations. Clin Nutr 2012; 31:783-800.
44. Nygren J, Thacker J, Carli F, et al. Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS(1)) Society recommendations. World J Surg 2013; 37:285-305.
45. Smith I, Kranke P, Murat I, et al. Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2011; 28:556-569.