Roles of miRNA-24 in regulating endothelial nitric oxide synthase expression and vascular endothelial cell proliferation

Molecular and Cellular Biochemistry

Volumn 405, Issue 1-2, 2015, Pages 281-289

  Zhang, Wenyu ^a   Yan, Limei ^b   Li, Yumei ^a   Chen, Wei ^a   Hu, Nan ^a   Wang, Hui ^a   Ou, Hesheng ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Cell proliferation; Endothelial nitric oxide synthase; miRNA 24; Sp1

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; LIPOSOME; MESSENGER RNA; MICRORNA 24; TRANSCRIPTION FACTOR SP1; MICRORNA; NOS3 PROTEIN, HUMAN;

ARTICLE; CELL COUNT; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENE FUNCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MTT ASSAY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING; CELL CULTURE; GENETICS; PHYSIOLOGY;

CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICRORNAS; NITRIC OXIDE SYNTHASE TYPE III; RNA, MESSENGER;

EID: 84929963999     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2418-y     Document Type: Article

References (26)

1. Jamaluddin MS, Liang Z, Lu J-M et al (2014) Roles of cardiovascular risk factors in endothelial nitric oxide synthase regulation: an update. Curr Pharm Des 20:3563–3578
2. Mo Q, Li D, Ling WH (2012) Effect of miR-18a on angiogenesis of human aortic endothelial cell. Chin J Pathophysiol 28:1187–1191
3. Costa A, Afonso J, Osório C et al (2013) miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells. J Hematol Oncol 6:87. doi:10.1186/1756-8722-6-87
4. Bao M-H, Feng X, Zhang Y-W et al (2013) Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells. Int J Mol Sci 14:23086–23102. doi:10.3390/ijms141123086
5. Roncarati R, Viviani Anselmi C, Losi MA et al (2014) Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 63:920–927. doi:10.1016/j.jacc.2013.09.041
6. Meloni M, Marchetti M, Garner K et al (2013) Local inhibition of microRNA-24 improves reparative angiogenesis and left ventricle remodeling and function in mice with myocardial infarction. Mol Ther 21:1390–1402. doi:10.1038/mt.2013.89
7. Arnal JF, Dinh-Xuan AT, Pueyo M et al (1999) Endothelium-derived nitric oxide and vascular physiology and pathology. Cell Mol Life Sci 55:1078–1087
8. Wang B, Xing F, Liu N et al (2014) p38α subtype is a potential target to inhibit eNOS activity and NO production in human endothelial cells. Microvasc Res 91:58–65. doi:10.1016/j.mvr.2013.10.007
9. Yang P, Zhang Y, Pang J et al (2013) Loss of Jak2 impairs endothelial function by attenuating Raf-1/MEK1/Sp-1 signaling along with altered eNOS activities. Am J Pathol 183:617–625. doi:10.1016/j.ajpath.2013.04.007
10. Huang PL (2009) eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrinol Metab 20:295–302. doi:10.1016/j.tem.2009.03.005
11. Kumar S, Sun X, Wiseman DA et al (2009) Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activity. DNA Cell Biol 28:119–129. doi:10.1089/dna.2008.0775
12. Ma Y, Wang B, Gong B et al (2013) MiR-24 improves beta-like globin gene expression through targeting Sp1. Sheng Wu Gong Cheng Xue Bao 29:946–954
13. Soodgupta D, Kaul D, Kanwar AJ et al (2014) Modulation of LXR-α and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes. Mol Cell Biochem 397:1–6. doi:10.1007/s11010-014-2063-x
14. Qian J, Fulton D (2013) Post-translational regulation of endothelial nitric oxide synthase in vascular endothelium. Front Physiol 4:347. doi:10.3389/fphys.2013.00347
15. Galluccio E, Cassina L, Russo I et al (2014) A novel truncated form of eNOS associates with altered vascular function. Cardiovasc Res 101:492–502. doi:10.1093/cvr/cvt267
16. Bandiera S, Hatem E, Lyonnet S, Henrion-Caude A (2010) microRNAs in diseases: from candidate to modifier genes. Clin Genet 77:306–313. doi:10.1111/j.1399-0004.2010.01370.x
17. Wang S, Aurora AB, Johnson BA et al (2008) The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell 15:261–271. doi:10.1016/j.devcel.2008.07.002
18. Anand S, Majeti BK, Acevedo LM et al (2010) MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med 16:909–914. doi:10.1038/nm.2186
19. Shi L, Fisslthaler B, Zippel N et al (2013) MicroRNA-223 antagonizes angiogenesis by targeting β1 integrin and preventing growth factor signaling in endothelial cells. Circ Res 113:1320–1330. doi:10.1161/CIRCRESAHA.113.301824
20. Wang J, Huang W, Xu R et al (2012) MicroRNA-24 regulates cardiac fibrosis after myocardial infarction. J Cell Mol Med 16:2150–2160. doi:10.1111/j.1582-4934.2012.01523.x
21. Yan L, Hao H, Elton TS et al (2011) Intronic microRNA suppresses endothelial nitric oxide synthase expression and endothelial cell proliferation via inhibition of STAT3 signaling. Mol Cell Biochem 357:9–19. doi:10.1007/s11010-011-0870-x
22. Liu H-F, Qi X-W, Ma L et al (2013) Atorvastatin improves endothelial progenitor cell function and reduces pulmonary hypertension in patients with chronic pulmonary heart disease. Exp Clin Cardiol 18:e40–e43
23. Bai X, Wang X, Xu Q (2010) Endothelial damage and stem cell repair in atherosclerosis. Vasc Pharmacol 52:224–229. doi:10.1016/j.vph.2010.02.001
24. Hobert O (2008) Gene regulation by transcription factors and microRNAs. Science 319:1785–1786. doi:10.1126/science.1151651
25. Makeyev EV, Maniatis T (2008) Multilevel regulation of gene expression by microRNAs. Science 319:1789–1790. doi:10.1126/science.1152326
26. Searles CD (2006) Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression. Am J Physiol Cell Physiol 291:C803–C816. doi:10.1152/ajpcell.00457.2005