A 3-D enteroid-based model to study T-cell and epithelial cell interaction

Journal of Immunological Methods

Volumn 421, Issue , 2015, Pages 89-95

  Rogoz, Aneta ^a   Reis, Bernardo S ^a   Karssemeijer, Roos A ^a   Mucida, Daniel ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

3 D cultures; Intestinal epithelial cells; Intraepithelial lymphocytes; T cells

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELL MOTION; COCULTURE; CONTROLLED STUDY; CRYPT CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; INTRACELLULAR SPACE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE STRUCTURE; MEMBRANE MARKER; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; T CELL CULTURE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; EPITHELIUM CELL; FLOW CYTOMETRY; IMMUNOLOGY; INTESTINE MUCOSA; LYMPHOCYTE ACTIVATION; TIGHT JUNCTION; TRANSGENIC MOUSE;

ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EPITHELIAL CELLS; FLOW CYTOMETRY; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; T-LYMPHOCYTES; TIGHT JUNCTIONS;

EID: 84929958175     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2015.03.014     Document Type: Article

References (23)

1. Cheroutre H., Lambolez F., Mucida D. The light and dark sides of intestinal intraepithelial lymphocytes. Nat. Rev. Immunol. 2011, 11:445.
2. Dotan I., Allez M., Nakazawa A., Brimnes J., Schulder-Katz M., Mayer L. Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292:G1630.
3. Edelblum K.L., Shen L., Weber C.R., Marchiando A.M., Clay B.S., Wang Y., Prinz I., Malissen B., Sperling A.I., Turner J.R. Dynamic migration of gammadelta intraepithelial lymphocytes requires occludin. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:7097.
4. Farache J., Koren I., Milo I., Gurevich I., Kim K.W., Zigmond E., Furtado G.C., Lira S.A., Shakhar G. Luminal bacteria recruit CD103+ dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity 2013, 38:581.
5. Fuchs A., Vermi W., Lee J.S., Lonardi S., Gilfillan S., Newberry R.D., Cella M., Colonna M. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells. Immunity 2013, 38:769.
6. Gallucci B.B., Sale G.E., McDonald G.B., Epstein R., Shulman H.M., Thomas E.D. The fine structure of human rectal epithelium in acute graft-versus-host disease. Am. J. Surg. Pathol. 1982, 6:293.
7. Guy-Grand D., Vassalli P., Eberl G., Pereira P., Burlen-Defranoux O., Lemaitre F., Di Santo J.P., Freitas A.A., Cumano A., Bandeira A. Origin, trafficking, and intraepithelial fate of gut-tropic T cells. J. Exp. Med. 2013, 210:1839.
8. Hershberg R., Eghtesady P., Sydora B., Brorson K., Cheroutre H., Modlin R., Kronenberg M. Expression of the thymus leukemia antigen in mouse intestinal epithelium. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:9727.
9. Huang Y., Park Y., Wang-Zhu Y., Larange A., Arens R., Bernardo I., Olivares-Villagomez D., Herndler-Brandstetter D., Abraham N., Grubeck-Loebenstein B., Schoenberger S.P., Van Kaer L., Kronenberg M., Teitell M.A., Cheroutre H. Mucosal memory CD8(+) T cells are selected in the periphery by an MHC class I molecule. Nat. Immunol. 2011, 12:1086.
10. Iwata M., Hirakiyama A., Eshima Y., Kagechika H., Kato C., Song S.Y. Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004, 21:527.
11. Jabri B., Sollid L.M. Tissue-mediated control of immunopathology in coeliac disease. Nat. Rev. Immunol. 2009, 9:858.
12. Kilshaw P.J., Murant S.J. A new surface antigen on intraepithelial lymphocytes in the intestine. Eur. J. Immunol. 1990, 20:2201.
13. Koo B.K., Stange D.E., Sato T., Karthaus W., Farin H.F., Huch M., van Es J.H., Clevers H. Controlled gene expression in primary Lgr5 organoid cultures. Nat. Methods 2012, 9:81.
14. Leishman A.J., Gapin L., Capone M., Palmer E., MacDonald H.R., Kronenberg M., Cheroutre H. Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. Immunity 2002, 16:355.
15. Mazzini E., Massimiliano L., Penna G., Rescigno M. Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1(+) macrophages to CD103(+) dendritic cells. Immunity 2014, 40:248.
16. Peterson L.W., Artis D. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat. Rev. Immunol. 2014, 14:141.
17. Reis B.S., Hoytema van Konijnenburg D.P., Grivennikov S.I., Mucida D. Transcription factor T-bet regulates intraepithelial lymphocyte functional maturation. Immunity 2014, 41:244.
18. Sato T., Clevers H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 2013, 340:1190.
19. Sato T., Vries R.G., Snippert H.J., van de Wetering M., Barker N., Stange D.E., van Es J.H., Abo A., Kujala P., Peters P.J., Clevers H. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009, 459:262.
20. Sato T., Stange D.E., Ferrante M., Vries R.G., Van Es J.H., Van den Brink S., Van Houdt W.J., Pronk A., Van Gorp J., Siersema P.D., Clevers H. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 2011, 141:1762.
21. Sato T., van Es J.H., Snippert H.J., Stange D.E., Vries R.G., van den Born M., Barker N., Shroyer N.F., van de Wetering M., Clevers H. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 2011, 469:415.
22. van Wijk F., Cheroutre H. Intestinal T cells: facing the mucosal immune dilemma with synergy and diversity. Semin. Immunol. 2009, 21:130.
23. Vezys V., Olson S., Lefrancois L. Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction. Immunity 2000, 12:505.