Lyophilized Sustained Release Mucoadhesive Chitosan Sponges for Buccal Buspirone Hydrochloride Delivery: Formulation and In Vitro Evaluation

AAPS PharmSciTech

Volumn 16, Issue 3, 2015, Pages 537-547

  Kassem, Mohamed A A ^a   ElMeshad, Aliaa N ^a   Fares, Ahmed R ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

buspirone HCL; casting freeze drying technique; chitosan; cup and core sponge; mucoadhesive buccal sponges

Indexed keywords

BUSPIRONE; CHITOSAN; DELAYED RELEASE FORMULATION;

ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; EX VIVO STUDY; FACTORIAL DESIGN; FREEZE DRYING; IN VITRO STUDY; INFRARED SPECTROSCOPY; MUCOADHESION; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DELAYED RELEASE FORMULATION; MEDICINAL CHEMISTRY; METABOLISM; MOUTH MUCOSA; PROCEDURES; SPONGE (PORIFERA);

ANIMALS; BIOLOGICAL AVAILABILITY; BUSPIRONE; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; FREEZE DRYING; MICROSCOPY, ELECTRON, SCANNING; MOUTH MUCOSA; PORIFERA;

EID: 84929956435     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-014-0243-3     Document Type: Article

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