-
1
-
-
84885126599
-
2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European league against rheumatism collaborative initiative
-
PID: 24092682
-
Van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE et al (2013) 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European league against rheumatism collaborative initiative. Ann Rheum Dis 72:1747–1755. doi:10.1136/annrheumdis-2013-204424
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 1747-1755
-
-
Van den Hoogen, F.1
Khanna, D.2
Fransen, J.3
Johnson, S.R.4
Baron, M.5
Tyndall, A.6
Matucci-Cerinic, M.7
Naden, R.P.8
Medsger, T.A.9
Carreira, P.E.10
-
2
-
-
84655175061
-
Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
-
COI: 1:CAS:528:DC%2BC3MXhs1GlsLvN
-
Bhattacharyya S, Wei J, Varga J (2012) Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities. Nat Rev Rheumatol 8:42–54. doi:10.1038/nrrheum.2011.149
-
(2012)
Nat Rev Rheumatol
, vol.8
, pp. 42-54
-
-
Bhattacharyya, S.1
Wei, J.2
Varga, J.3
-
3
-
-
33847348491
-
Systemic sclerosis: a prototypic multisystem fibrotic disorder
-
COI: 1:CAS:528:DC%2BD2sXis12htrw%3D, PID: 17332883
-
Varga J, Abraham D (2007) Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 117:557–567. doi:10.1172/jci31139
-
(2007)
J Clin Invest
, vol.117
, pp. 557-567
-
-
Varga, J.1
Abraham, D.2
-
4
-
-
33846573898
-
Fibroblast differentiation in wound healing and fibrosis
-
COI: 1:CAS:528:DC%2BD2sXmt1Glu70%3D, PID: 17280897
-
Darby IA, Hewitson TD (2007) Fibroblast differentiation in wound healing and fibrosis. Int Rev Cytol 257:143–179. doi:10.1016/s0074-7696(07)57004-x
-
(2007)
Int Rev Cytol
, vol.257
, pp. 143-179
-
-
Darby, I.A.1
Hewitson, T.D.2
-
5
-
-
0037899249
-
The myofibroblast in wound healing and fibrocontractive diseases
-
COI: 1:STN:280:DC%2BD3szhsFOrtg%3D%3D, PID: 12845617
-
Gabbiani G (2003) The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 200:500–503. doi:10.1002/path.1427
-
(2003)
J Pathol
, vol.200
, pp. 500-503
-
-
Gabbiani, G.1
-
6
-
-
34447271736
-
Transforming growth factor-beta and fibrosis
-
COI: 1:CAS:528:DC%2BD2sXhtFyjt7%2FO, PID: 17589920
-
Verrecchia F, Mauviel A (2007) Transforming growth factor-beta and fibrosis. World J Gastroenterol 13:3056–3062
-
(2007)
World J Gastroenterol
, vol.13
, pp. 3056-3062
-
-
Verrecchia, F.1
Mauviel, A.2
-
7
-
-
0036391801
-
The Abl family kinases: mechanisms of regulation and signaling
-
COI: 1:CAS:528:DC%2BD38XpsVyisrc%3D, PID: 12374288
-
Pendergast AM (2002) The Abl family kinases: mechanisms of regulation and signaling. Adv Cancer Res 85:51–100. doi:10.1016/S0065-230X(02)85003-5
-
(2002)
Adv Cancer Res
, vol.85
, pp. 51-100
-
-
Pendergast, A.M.1
-
8
-
-
33748760321
-
Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures
-
COI: 1:CAS:528:DC%2BD28XpsFOrt7Y%3D, PID: 16867995
-
Wilkes MC, Leof EB (2006) Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures. J Biol Chem 281:27846–27854. doi:10.1074/jbc.M603721200
-
(2006)
J Biol Chem
, vol.281
, pp. 27846-27854
-
-
Wilkes, M.C.1
Leof, E.B.2
-
9
-
-
15244339164
-
Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis
-
COI: 1:CAS:528:DC%2BD2cXpsFCgtrg%3D, PID: 15520863
-
Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB (2004) Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J Clin Invest 114:1308–1316. doi:10.1172/jci19603
-
(2004)
J Clin Invest
, vol.114
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
Leof, E.B.7
-
10
-
-
11244292291
-
Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo
-
PID: 15629889
-
Wang S, Wilkes MC, Leof EB, Hirschberg R (2005) Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo. FASEB J 19:1–11. doi:10.1096/fj.04-2370com
-
(2005)
FASEB J
, vol.19
-
-
Wang, S.1
Wilkes, M.C.2
Leof, E.B.3
Hirschberg, R.4
-
11
-
-
0034625363
-
Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species
-
COI: 1:CAS:528:DC%2BD3cXktFalu7k%3D, PID: 10770918
-
Sun X, Majumder P, Shioya H, Wu F, Kumar S, Weichselbaum R, Kharbanda S, Kufe D (2000) Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. J Biol Chem 275:17237–17240. doi:10.1074/jbc.C000099200
-
(2000)
J Biol Chem
, vol.275
, pp. 17237-17240
-
-
Sun, X.1
Majumder, P.2
Shioya, H.3
Wu, F.4
Kumar, S.5
Weichselbaum, R.6
Kharbanda, S.7
Kufe, D.8
-
12
-
-
84856060485
-
PDGF upregulates Mcl-1 through activation of beta-catenin and HIF-1alpha-dependent signaling in human prostate cancer cells
-
COI: 1:CAS:528:DC%2BC38XitFeisLY%3D, PID: 22276222
-
Iqbal S, Zhang S, Driss A, Liu ZR, Kim HR, Wang Y, Ritenour C, Zhau HE, Kucuk O, Chung LW et al (2012) PDGF upregulates Mcl-1 through activation of beta-catenin and HIF-1alpha-dependent signaling in human prostate cancer cells. PLoS ONE 7:e30764. doi:10.1371/journal.pone.0030764
-
(2012)
PLoS ONE
, vol.7
, pp. e30764
-
-
Iqbal, S.1
Zhang, S.2
Driss, A.3
Liu, Z.R.4
Kim, H.R.5
Wang, Y.6
Ritenour, C.7
Zhau, H.E.8
Kucuk, O.9
Chung, L.W.10
-
13
-
-
0142214549
-
Biochemistry of apoptotic cell death
-
COI: 1:CAS:528:DC%2BD3sXoslKhsLw%3D, PID: 14769239
-
Barisic K, Petrik J, Rumora L (2003) Biochemistry of apoptotic cell death. Acta Pharm 53:151–164
-
(2003)
Acta Pharm
, vol.53
, pp. 151-164
-
-
Barisic, K.1
Petrik, J.2
Rumora, L.3
-
14
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
COI: 1:CAS:528:DyaK1MXltlGktrg%3D, PID: 10444588
-
Gross A, McDonnell JM, Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899–1911
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
15
-
-
0023854176
-
Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
-
COI: 1:STN:280:DyaL1c3gtVWnsg%3D%3D, PID: 3361530
-
LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr, Rowell N, Wollheim F (1988) Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 15:202–205
-
(1988)
J Rheumatol
, vol.15
, pp. 202-205
-
-
LeRoy, E.C.1
Black, C.2
Fleischmajer, R.3
Jablonska, S.4
Krieg, T.5
Medsger, T.A.6
Rowell, N.7
Wollheim, F.8
-
16
-
-
39549098706
-
Establishment of fibroblast cultures
-
COI: 1:STN:280:DC%2BD1c%2FntFKltA%3D%3D, PID: 18228346
-
Takashima A (2001) Establishment of fibroblast cultures. Curr Protoc Cell Biol Chapter 2:Unit 2.1. doi:10.1002/0471143030.cb0201s00
-
(2001)
Curr Protoc Cell Biol
-
-
Takashima, A.1
-
17
-
-
44949231424
-
Analyzing real-time PCR data by the comparative C(T) method
-
COI: 1:CAS:528:DC%2BD1cXmvVemt7c%3D, PID: 18546601
-
Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3:1101–1108. doi:10.1038/nprot.2008.73
-
(2008)
Nat Protoc
, vol.3
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
18
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
COI: 1:CAS:528:DyaE28XksVehtrY%3D, PID: 942051
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254. doi:10.1016/0003-2697(76)90527-3
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
19
-
-
0033067492
-
Transforming growth factor beta and tumor necrosis factor alpha inhibit both apoptosis and proliferation of activated rat hepatic stellate cells
-
COI: 1:CAS:528:DyaK1MXksVOqsLc%3D, PID: 10385656
-
Saile B, Matthes N, Knittel T, Ramadori G (1999) Transforming growth factor beta and tumor necrosis factor alpha inhibit both apoptosis and proliferation of activated rat hepatic stellate cells. Hepatology 30:196–202. doi:10.1002/hep.510300144
-
(1999)
Hepatology
, vol.30
, pp. 196-202
-
-
Saile, B.1
Matthes, N.2
Knittel, T.3
Ramadori, G.4
-
20
-
-
0030788803
-
Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells
-
Dybedal I, Guan F, Borge OJ, Veiby OP, Ramsfjell V, Nagata S, Jacobsen SE (1997) Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells. Blood 90(9):3395–3403
-
(1997)
Blood
, vol.90
, Issue.9
, pp. 3395-3403
-
-
Dybedal, I.1
Guan, F.2
Borge, O.J.3
Veiby, O.P.4
Ramsfjell, V.5
Nagata, S.6
Jacobsen, S.E.7
-
21
-
-
0033258047
-
Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)
-
COI: 1:CAS:528:DC%2BD3cXhslemtg%3D%3D, PID: 10572062
-
Zhang HY, Phan SH (1999) Inhibition of myofibroblast apoptosis by transforming growth factor beta(1). Am J Respir Cell Mol Biol 21:658–665. doi:10.1165/ajrcmb.21.6.3720
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 658-665
-
-
Zhang, H.Y.1
Phan, S.H.2
-
22
-
-
0029872210
-
Apoptosis induced by transforming growth factor-beta in fetal hepatocyte primary cultures: involvement of reactive oxygen intermediates
-
COI: 1:CAS:528:DyaK28XhvFyksrg%3D, PID: 8631767
-
Sanchez A, Alvarez AM, Benito M, Fabregat I (1996) Apoptosis induced by transforming growth factor-beta in fetal hepatocyte primary cultures: involvement of reactive oxygen intermediates. J Biol Chem 271:7416–7422. doi:10.1074/jbc.271.13.7416
-
(1996)
J Biol Chem
, vol.271
, pp. 7416-7422
-
-
Sanchez, A.1
Alvarez, A.M.2
Benito, M.3
Fabregat, I.4
-
24
-
-
0037097680
-
TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells
-
COI: 1:CAS:528:DC%2BD38XksFWmu7s%3D, PID: 12055267
-
Hagimoto N, Kuwano K, Inoshima I, Yoshimi M, Nakamura N, Fujita M, Maeyama T, Hara N (2002) TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J Immunol 168:6470–6478. doi:10.4049/jimmunol.168.12.6470
-
(2002)
J Immunol
, vol.168
, pp. 6470-6478
-
-
Hagimoto, N.1
Kuwano, K.2
Inoshima, I.3
Yoshimi, M.4
Nakamura, N.5
Fujita, M.6
Maeyama, T.7
Hara, N.8
-
25
-
-
0037464449
-
Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli
-
COI: 1:CAS:528:DC%2BD3sXjtFWrtrg%3D, PID: 12706819
-
Brumatti G, Weinlich R, Chehab CF, Yon M, Amarante-Mendes GP (2003) Comparison of the anti-apoptotic effects of Bcr-Abl, Bcl-2 and Bcl-x(L) following diverse apoptogenic stimuli. FEBS Lett 541:57–63. doi:10.1016/S0014-5793(03)00299-0
-
(2003)
FEBS Lett
, vol.541
, pp. 57-63
-
-
Brumatti, G.1
Weinlich, R.2
Chehab, C.F.3
Yon, M.4
Amarante-Mendes, G.P.5
-
26
-
-
0037309894
-
Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571
-
COI: 1:CAS:528:DC%2BD3sXnvV2hsg%3D%3D, PID: 12527798
-
Kumar S, Mishra N, Raina D, Saxena S, Kufe D (2003) Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571. Mol Pharmacol 63:276–282. doi:10.1124/mol.63.2.276
-
(2003)
Mol Pharmacol
, vol.63
, pp. 276-282
-
-
Kumar, S.1
Mishra, N.2
Raina, D.3
Saxena, S.4
Kufe, D.5
-
27
-
-
33646480748
-
Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor
-
COI: 1:CAS:528:DC%2BD28XksFarurc%3D, PID: 16631755
-
Lasfer M, Davenne L, Vadrot N, Alexia C, Sadji-Ouatas Z, Bringuier AF, Feldmann G, Pessayre D, Reyl-Desmars F (2006) Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor. FEBS Lett 580:2547–2552. doi:10.1016/j.febslet.2006.03.089
-
(2006)
FEBS Lett
, vol.580
, pp. 2547-2552
-
-
Lasfer, M.1
Davenne, L.2
Vadrot, N.3
Alexia, C.4
Sadji-Ouatas, Z.5
Bringuier, A.F.6
Feldmann, G.7
Pessayre, D.8
Reyl-Desmars, F.9
-
28
-
-
33846209989
-
Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
-
COI: 1:CAS:528:DC%2BD2sXhsFaisL4%3D, PID: 17195235
-
Distler JH, Jungel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S et al (2007) Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum 56:311–322. doi:10.1002/art.22314
-
(2007)
Arthritis Rheum
, vol.56
, pp. 311-322
-
-
Distler, J.H.1
Jungel, A.2
Huber, L.C.3
Schulze-Horsel, U.4
Zwerina, J.5
Gay, R.E.6
Michel, B.A.7
Hauser, T.8
Schett, G.9
Gay, S.10
-
29
-
-
46749154199
-
Dual inhibition of c-Abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis
-
COI: 1:CAS:528:DC%2BD1cXotlanurg%3D, PID: 18326784
-
Akhmetshina A, Dees C, Pileckyte M, Maurer B, Axmann R, Jungel A, Zwerina J, Gay S, Schett G, Distler O et al (2008) Dual inhibition of c-Abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis. FASEB J 22:2214–2222. doi:10.1096/fj.07-105627
-
(2008)
FASEB J
, vol.22
, pp. 2214-2222
-
-
Akhmetshina, A.1
Dees, C.2
Pileckyte, M.3
Maurer, B.4
Axmann, R.5
Jungel, A.6
Zwerina, J.7
Gay, S.8
Schett, G.9
Distler, O.10
-
30
-
-
84925535774
-
Attenuation of fibrosis with selective inhibition of c-Abl by siRNA in systemic sclerosis dermal fibroblasts
-
COI: 1:CAS:528:DC%2BC2cXitFOrsLzK, PID: 25527259
-
Karimizadeh E, Motamed N, Mahmoudi M, Jafarinejad-Farsangi S, Jamshidi A, Faridani H, Gharibdoost F (2015) Attenuation of fibrosis with selective inhibition of c-Abl by siRNA in systemic sclerosis dermal fibroblasts. Arch Dermatol Res 307:135–142. doi:10.1007/s00403-014-1532-0
-
(2015)
Arch Dermatol Res
, vol.307
, pp. 135-142
-
-
Karimizadeh, E.1
Motamed, N.2
Mahmoudi, M.3
Jafarinejad-Farsangi, S.4
Jamshidi, A.5
Faridani, H.6
Gharibdoost, F.7
-
31
-
-
0035720233
-
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
-
COI: 1:CAS:528:DC%2BD3MXmvVyjsbo%3D, PID: 11511312
-
Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC (2001) The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. J Invest Dermatol 117:333–340. doi:10.1046/j.0022-202x.2001.01409.x
-
(2001)
J Invest Dermatol
, vol.117
, pp. 333-340
-
-
Raisova, M.1
Hossini, A.M.2
Eberle, J.3
Riebeling, C.4
Wieder, T.5
Sturm, I.6
Daniel, P.T.7
Orfanos, C.E.8
Geilen, C.C.9
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