Structural basis of cofactor-mediated stabilization and substrate recognition of the α-tubulin acetyltransferase αTAT1

Biochemical Journal

Volumn 467, Issue 1, 2015, Pages 103-113

  Yuzawa, Satoru ^a   Kamakura, Sachiko ^a   Hayase, Junya ^a   Sumimoto, Hideki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Coenzyme A; Crystal structure; Mechanosensory (MEC) 17; Substrate recognition; tubulin acetyltransferase 1 ( TAT1)

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; ALANINE; ALPHA TUBULIN; ALPHA TUBULIN ACETYLTRANSFERASE 1; ARGININE; COENZYME A; HISTONE ACETYLTRANSFERASE; UNCLASSIFIED DRUG; ALPHA-TUBULIN ACETYLASE; HYBRID PROTEIN; MUTANT PROTEIN; PEPTIDE FRAGMENT; SERINE; TUBA1A PROTEIN, HUMAN; TUBULIN;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME METABOLISM; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; HUMAN; HYDROGEN BOND; MUTATIONAL ANALYSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; AMINO ACID SUBSTITUTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; DOG; ENZYME SPECIFICITY; GENETICS; MDCK CELL LINE; METABOLISM; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; MAMMALIA;

ACETYL COENZYME A; ACETYLTRANSFERASES; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; CATALYTIC DOMAIN; COENZYME A; CRYSTALLOGRAPHY, X-RAY; DOGS; ENZYME STABILITY; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTANT PROTEINS; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; SERINE; SUBSTRATE SPECIFICITY; TUBULIN;

EID: 84929939021     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141193     Document Type: Article

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