Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: A mechanism possibly involved in hereditary multiple exostoses

American Journal of Pathology

Volumn 185, Issue 6, 2015, Pages 1676-1685

  Huegel, Julianne ^a   Enomoto Iwamoto, Motomi ^a   Sgariglia, Federica ^a   Koyama, Eiki ^a   Pacifici, Maurizio ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DNA; HEPARANASE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RNA; RONEPARSTAT; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; BETA GLUCURONIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; DNA CONTENT; DOSE RESPONSE; EARLY RESPONSE GENE; EMBRYO; GENE EXPRESSION; HEREDITARY MULTIPLE EXOSTOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MONOLAYER CULTURE; MOUSE; MOUSE EMBRYO; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; UPREGULATION; ANIMAL; CELL MOTION; CHILD; CHONDROCYTE; DRUG EFFECTS; EPIPHYSIS PLATE; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; CARTILAGE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHILD; CHONDROCYTES; CHONDROGENESIS; EXOSTOSES, MULTIPLE HEREDITARY; GLUCURONIDASE; GROWTH PLATE; HUMANS; MICE; UP-REGULATION;

EID: 84929922704     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.02.014     Document Type: Article

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