Functional analysis of potassium channels in Kv7.2 G271V mutant causing early onset familial epilepsy

Brain Research

Volumn 1616, Issue , 2015, Pages 112-122

  Wang, Juanjuan ^a,b   Li, Yuan ^a   Hui, Zhiyan ^a,b   Cao, Min ^a   Shi, Ruiming ^b   Zhang, Wei ^a,b   Geng, Limeng ^b   Zhou, Xihui ^a,b  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Epilepsy; KCNQ2; Kv7.2; Patch clamp electrophysiology; Voltage gated potassium channel

Indexed keywords

POTASSIUM CHANNEL; ANTICONVULSIVE AGENT; CARBAMIC ACID DERIVATIVE; GLYCINE; GREEN FLUORESCENT PROTEIN; PHENYLENEDIAMINE DERIVATIVE; POTASSIUM CHANNEL KCNQ2; RETIGABINE; VALINE;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEPOLARIZATION; DISEASE SEVERITY; EPILEPSY; FLUORESCENCE MICROSCOPY; GENE MUTATION; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; KINETICS; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; BIOPHYSICS; DOSE RESPONSE; DRUG EFFECTS; ELECTROSTIMULATION; GENETICS; MEMBRANE POTENTIAL; METABOLISM; MUTAGENESIS; MUTATION; PHYSIOLOGY; TIME FACTOR;

ANTICONVULSANTS; BIOPHYSICAL PHENOMENA; CARBAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GLYCINE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; KCNQ2 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MUTAGENESIS; MUTATION; PATCH-CLAMP TECHNIQUES; PHENYLENEDIAMINES; TIME FACTORS; VALINE;

EID: 84929913632     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.04.060     Document Type: Article

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