Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy

Journal of Biological Chemistry

Volumn 275, Issue 18, 2000, Pages 13343-13348

  Schwake, Michael ^a   Pusch, Michael ^b   Kharkovets, Tatjana ^a   Jentsch, Thomas J ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CONVULSION; EPILEPSY; GENE MUTATION; MISSENSE MUTATION; NERVE CELL EXCITABILITY; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS;

ANIMALS; EPILEPSY; GENE EXPRESSION REGULATION; HUMANS; ION CHANNEL GATING; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; MUTATION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED;

ANIMALIA;

EID: 0034607698     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.18.13343     Document Type: Article

References (27)

1. Wang, Q., Curran, M. E., Splawski, I., Burn, T. C., Millholland, J. M., Van-Raay, T. J., Shen, J., Timothy, K. W., Vincent, G. M., de Jager, T., Schwartz, P. J., Toubin, J. A., Moss, A. J., Atkinson, D. L., Landes, G. M., Connors, T. D., and Keating, M. T. (1996) Nat. Genet. 12, 17-23
2. Neyroud, N., Tesson, F., Denjoy, I., Leibovici, M., Donger, C., Barhanin, J., Faure, S., Gary, F., Coumel, P., Petit, C., Schwartz, K., and Guicheney, P. (1997) Nat. Genet. 15, 186-189
3. Kubisch, C., Schroeder, B. C., Friedrich, T., Lütjohann, B., El-Amraoui, A., Marlin, S., Petit, C., and Jentsch, T. J. (1999) Cell 96, 437-446
4. Biervert, C., Schroeder, B. C., Kubisch, C., Berkovic, S. F., Propping, P., Jentsch, T. J., and Steinlein, O. K. (1998) Science 279, 403-406
5. Singh, N. A., Charlier, C., Stauffer, D., DuPont, B. R., Leach, R. J., Melis, R., Ronen, G. M., Bjerre, I., Quattlebaum, T., Murphy, J. V., McHarg, M. L., Gagnon, D., Rosales, T. O., Peiffer, A., Andersen, V. E., and Leppert, M. (1998) Nat. Genet. 18, 25-29
6. Charlier, C., Singh, N. A., Ryan, S, G., Lewis, T. B., Reus, B. E., Leach, R. J., and Leppert, M. (1998) Nat. Genet. 18, 53-55
7. Schroeder, B. C., Kubisch, C., Stein, V., and Jentsch, T. J. (1998) Nature 396, 687-690
8. Tinel, N., Lauritzen, I., Chouabe, C., Lazdunski, M., and Borsotto, M. (1998) FEBS Lett. 438, 171-176
9. Yang, W.-P., Levesque, P. C., Little, W. A., Conder, M. L., Ramakrishnan, P., Neubauer, M. G., and Blanar, M. A. (1998) J. Biol. Chem. 273, 19419-19423
10. Wang, H. S., Pan, Z., Shi, W., Brown, B. S., Wymore, R. S., Cohen, I. S., Dixon, J. E., and McKinnon, D. (1998) Science 282, 1890-1893
11. Marrion, N. V. (1997) Annu. Rev. Physiol. 59, 483-504
12. Selyanko, A. A., Hadley, J. K., Wood, I. C., Abogadie, F. C., Delmas, P., Buckley, N. J., London, B., and Brown, D. A. (1999) J. Neurosci. 19, 7742-7756
13. Meves, H., Schwarz, J. R., and Wulfsen, I. (1999) Br. J. Pharmacol. 127, 1213-1223
14. Zerangue, N., Schwappach, B., Jan, Y. N., and Jan, L. Y. (1999) Neuron 22, 537-548
15. Lorenz, C., Pusch, M., and Jentsch, T. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13362-13366
16. Pusch, M. (1998) Pflügers Arch. 437, 172-174
17. Pusch, M., Steinmeyer, K., and Jentsch, T. J. (1994) Biophys. J. 66, 149-152
18. Steinmeyer, K., Schwappach, B., Bens, M., Vandewalle, A., and Jentsch, T. J. (1995) J. Biol. Chem. 270, 31172-31177
19. Selyanko, A. A., Stansfeld, C. E., and Brown, D. A. (1992) Proc. R. Soc. Lond. B Biol. Sci. 250, 119-125
20. Selyanko, A. A., and Brown, D. A. (1993) J. Physiol. (Lond. ) 472, 711-724
21. Selyanko, A. A., and Brown, D. A. (1996) Neuron 16, 151-162
22. Selyanko, A. A., and Sim, J. A. (1998) J. Physiol. (Lond.) 510, 71-91
23. Goldman, D. E. (1943) J. Gen. Physiol. 27, 37-60
24. Wollnik, B., Schroeder, B. C., Kubisch, C., Esperer, H. D., Wieacker, P., and Jentsch, T. J. (1997) Hum. Mol. Genet. 6, 1943-1949
25. Canessa, C. M., Horisberger, J. D., and Rossier, B. C. (1993) Nature 361, 467-470
26. Canessa, C. M., Schild, L., Buell, G., Thorens, B., Gautschi, I., Horisberger, J. D., and Rossier, B. C. (1994) Nature 367, 463-467
27. Firsov, D., Schild, L., Gautschi. I., Merillat, A. M., Schneeberger, E., and Rossier, B. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 15370-15375