The epithelial danger signal IL-1α is a potent activator of fibroblasts and reactivator of intestinal inflammation

American Journal of Pathology

Volumn 185, Issue 6, 2015, Pages 1624-1637

  Scarpa, Melania ^a   Kessler, Sean ^a   Sadler, Tammy ^a   West, Gail ^a   Homer, Craig ^a   McDonald, Christine ^a,c   De La Motte, Carol ^a,b   Fiocchi, Claudio ^a,b   Stylianou, Eleni ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Digestive Disease Institute   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; DEXTRAN SULFATE; DNA; ENEMA; GENOMIC DNA; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 6; INTERLEUKIN 8; PROTEINASE K; RIBONUCLEASE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; URIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CELL LYSATE; CHROMATIN; COLITIS; COMPARATIVE STUDY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ACTIVITY; DISEASE EXACERBATION; DISEASE SEVERITY; DNA EXTRACTION; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATORY BOWEL DISEASE; INTESTINE EPITHELIUM CELL; MALE; MESENCHYME CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; ULCERATIVE COLITIS; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; HT-29 CELL LINE; INFLAMMATION; INTESTINE; METABOLISM; PATHOLOGY;

ANIMALS; COLITIS; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; FIBROBLASTS; HT29 CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-1ALPHA; INTERLEUKIN-6; INTERLEUKIN-8; INTESTINES; MICE;

EID: 84929906046     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.02.018     Document Type: Article

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